STRINGSTRING
gluQ gluQ CCF61196.1 CCF61196.1 tilS tilS panC panC cysS cysS CCF61528.1 CCF61528.1 guaA guaA trpS trpS argS argS valS valS nadD nadD cysD cysD cysH cysH CCF62323.1 CCF62323.1 CCF62358.1 CCF62358.1 phr phr asnB asnB ileS ileS CCF62895.1 CCF62895.1 argG argG tyrS tyrS CCF63144.1 CCF63144.1 cysD-2 cysD-2 CCF63465.1 CCF63465.1 cysS-2 cysS-2 uspA uspA CCF63668.1 CCF63668.1 CCF63674.1 CCF63674.1 CCF63676.1 CCF63676.1 CCF63679.1 CCF63679.1 hldE-2 hldE-2 CCF64168.1 CCF64168.1 ribF ribF kdpD kdpD coaD coaD gltX gltX trmU trmU CCF64803.1 CCF64803.1 CCF64804.1 CCF64804.1 nadE nadE metG metG CCF66078.1 CCF66078.1 leuS leuS CCF66260.1 CCF66260.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gluQGlutamyl-Q tRNA(Asp) synthetase (Glu-Q-RSs); Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (310 aa)
CCF61196.1Protein of unknown function; No homology to any previously reported sequences. (336 aa)
tilStRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase) (tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (350 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (309 aa)
cysScysteinyl-tRNA synthetase; Function of strongly homologous gene; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (468 aa)
CCF61528.1Homologs of previously reported genes of unknown function. (293 aa)
guaAGMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. (524 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (342 aa)
argSarginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. (537 aa)
valSValyl-tRNA synthetase (Valine--tRNA ligase) (ValRS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (864 aa)
nadDNicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
cysDSulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (309 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (239 aa)
CCF62323.1Homologs of previously reported genes of unknown function. (206 aa)
CCF62358.1Homologs of previously reported genes of unknown function. (149 aa)
phrDeoxyribodipyrimidine photo-lyase (DNA photolyase) (Photoreactivating enzyme); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DNA photolyase family. (442 aa)
asnBAsparagine synthetase; Function of strongly homologous gene; enzyme. (630 aa)
ileSIsoleucyl-tRNA synthetase (Isoleucine--tRNA ligase) (IleRS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1049 aa)
CCF62895.1Putative universal stress response protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (150 aa)
argGArgininosuccinate synthase (Citrulline--aspartate ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
tyrSTyrosyl-tRNA synthetase (Tyrosine--tRNA ligase) (TyrRS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (430 aa)
CCF63144.1Homologs of previously reported genes of unknown function. (284 aa)
cysD-2Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (310 aa)
CCF63465.1Homologs of previously reported genes of unknown function. (210 aa)
cysS-2cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2) (CysRS 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (394 aa)
uspAUniversal stress protein; Function of strongly homologous gene; cell process. (248 aa)
CCF63668.1Putative universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (321 aa)
CCF63674.1Putative universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (249 aa)
CCF63676.1Putative universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (300 aa)
CCF63679.1Putative universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (290 aa)
hldE-2Heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (497 aa)
CCF64168.1Homologs of previously reported genes of unknown function. (286 aa)
ribFBifunctional riboflavin kinase/FMN adenylyltransferase; Function of strongly homologous gene; enzyme; Belongs to the ribF family. (305 aa)
kdpDSensor protein kdpD; Function of strongly homologous gene; regulator. (865 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
gltXGlutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (490 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (360 aa)
CCF64803.1Putative electron transfer flavoprotein alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (313 aa)
CCF64804.1Putative electron transfer flavoprotein beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (261 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (520 aa)
CCF66078.1Homologs of previously reported genes of unknown function. (155 aa)
leuSLeucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (957 aa)
CCF66260.1Homologs of previously reported genes of unknown function. (222 aa)
Your Current Organism:
Nocardia cyriacigeorgica
NCBI taxonomy Id: 1127134
Other names: N. cyriacigeorgica GUH-2, Nocardia cyriacigeorgica GUH-2, Nocardia cyriacigeorgica str. GUH-2, Nocardia cyriacigeorgica strain GUH-2
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