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| | AFT97985.1 | COG0512 Anthranilate/para-aminobenzoate synthases component II. (214 aa) |
| | AFT98014.1 | COG1605 Chorismate mutase. (206 aa) |
| | AFT98015.1 | COG0067 Glutamate synthase domain 1. (1549 aa) |
| | gltD | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (489 aa) |
| | pheA | COG0077 Prephenate dehydratase. (304 aa) |
| | pat | Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa) |
| | AFT98174.1 | COG0287 Prephenate dehydrogenase. (301 aa) |
| | AFT98285.1 | COG0527 Aspartokinases; Belongs to the aspartokinase family. (421 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | AFT98336.1 | Putative hydrolase; COG0560 Phosphoserine phosphatase. (268 aa) |
| | AFT98587.1 | COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (467 aa) |
| | AFT98660.1 | Salicylate synthase MbtI; COG0147 Anthranilate/para-aminobenzoate synthases component I. (437 aa) |
| | AFT98664.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (344 aa) |
| | AFT98669.1 | Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (390 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (374 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (386 aa) |
| | AFT99001.1 | COG2873 O-acetylhomoserine sulfhydrylase. (442 aa) |
| | phhA | COG3186 Phenylalanine-4-hydroxylase. (299 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (474 aa) |
| | AFT99200.1 | COG0460 Homoserine dehydrogenase. (429 aa) |
| | AFT99201.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (321 aa) |
| | AFT99542.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (394 aa) |
| | AFT99571.1 | COG0019 Diaminopimelate decarboxylase. (423 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (447 aa) |
| | AFT99673.1 | COG1171 Threonine dehydratase. (322 aa) |
| | AFT99679.1 | COG2902 NAD-specific glutamate dehydrogenase. (1650 aa) |
| | AFT99696.1 | COG0308 Aminopeptidase N. (859 aa) |
| | AFT99737.1 | COG2873 O-acetylhomoserine sulfhydrylase. (437 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa) |
| | AFT99798.1 | Dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (316 aa) |
| | AFT99806.1 | Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (356 aa) |
| | AFT99807.1 | COG0174 Glutamine synthetase. (455 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | AFU00035.1 | COG0512 Anthranilate/para-aminobenzoate synthases component II. (743 aa) |
| | AFU00049.1 | COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (388 aa) |
| | AFU00112.1 | Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (391 aa) |
| | AFU00161.1 | Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (346 aa) |
| | AFU00184.1 | Hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. (325 aa) |
| | AFU00189.1 | COG0174 Glutamine synthetase. (446 aa) |
| | glnE | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] (1003 aa) |
| | AFU00205.1 | COG0174 Glutamine synthetase. (478 aa) |
| | pepA | Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa) |
| | gcvT | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (366 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa) |
| | AFU00265.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (461 aa) |
| | AFU00274.1 | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (294 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (451 aa) |
| | AFU00418.1 | COG0031 Cysteine synthase. (319 aa) |
| | hisD | Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (445 aa) |
| | hisC | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (377 aa) |
| | hisB | COG0131 Imidazoleglycerol-phosphate dehydratase. (205 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | hisA | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (243 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (115 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (519 aa) |
| | trpC | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (272 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | AFU00545.1 | Cystathionine beta-synthase; COG0031 Cysteine synthase. (368 aa) |
| | AFU00599.1 | COG0405 Gamma-glutamyltransferase. (593 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (364 aa) |
| | argJ | Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (308 aa) |
| | argD | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa) |
| | AFU00668.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (322 aa) |
| | argR | Arginine repressor ArgR; Regulates arginine biosynthesis genes. (162 aa) |
| | argG | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa) |
| | argH | COG0165 Argininosuccinate lyase. (473 aa) |
| | AFU00679.1 | COG1171 Threonine dehydratase. (411 aa) |
| | katG | Catalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (742 aa) |
| | AFU01093.1 | Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. (382 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (315 aa) |
| | AFU01262.1 | COG0506 Proline dehydrogenase. (322 aa) |
| | AFU01263.1 | COG1012 NAD-dependent aldehyde dehydrogenases. (545 aa) |
| | AFU01397.1 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (330 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (132 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (936 aa) |
| | AFU01638.1 | FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. (796 aa) |
| | solA | COG0665 Glycine/D-amino acid oxidases (deaminating). (382 aa) |
| | glyA-3 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (440 aa) |
| | AFU01647.1 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | katG-2 | Catalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (741 aa) |
| | AFU01786.1 | Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (368 aa) |
| | AFU01791.1 | FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). (436 aa) |
| | AFU01823.1 | COG0174 Glutamine synthetase. (436 aa) |
| | AFU02179.1 | Aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (387 aa) |
| | AFU02198.1 | L-tyosine 3-hydroxylase. (282 aa) |
| | AFU02204.1 | COG0405 Gamma-glutamyltransferase. (599 aa) |
| | AFU02233.1 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (401 aa) |
| | AFU02237.1 | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa) |
| | AFU02267.1 | Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (365 aa) |
| | AFU02272.1 | Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. (396 aa) |
| | ahcY | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (484 aa) |
| | glyA | COG0112 Glycine/serine hydroxymethyltransferase. (615 aa) |
| | AFU02332.1 | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (327 aa) |
| | AFU02423.1 | Sarcosine oxidase, alpha subunit SoxA; COG0665 Glycine/D-amino acid oxidases (deaminating). (373 aa) |
| | AFU02672.1 | Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (255 aa) |
| | AFU02682.1 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (367 aa) |
| | AFU02684.1 | Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (346 aa) |
| | AFU02688.1 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (369 aa) |
| | AFU02703.1 | COG2902 NAD-specific glutamate dehydrogenase. (1535 aa) |
| | AFU02730.1 | Class I/II aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (521 aa) |
| | AFU02824.1 | COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (297 aa) |
| | AFU02943.1 | 2-amino-3-ketobutyrate coenzyme A ligase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (392 aa) |
| | AFU02969.1 | COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (336 aa) |
| | AFU03203.1 | COG4992 Ornithine/acetylornithine aminotransferase. (686 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa) |
| | hisE | COG0140 Phosphoribosyl-ATP pyrophosphohydrolase. (87 aa) |
| | AFU03365.1 | Hypothetical protein; COG3404 Methenyl tetrahydrofolate cyclohydrolase. (219 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | AFU03482.1 | Putative D-methionine-binding lipoprotein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. (288 aa) |
| | AFU03483.1 | Lipoprotein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. (291 aa) |
| | metN | ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (337 aa) |
| | AFU03485.1 | ABC transporter permease; COG2011 ABC-type metal ion transport system, permease component. (220 aa) |
| | AFU03510.1 | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. (330 aa) |
| | AFU03526.1 | Arogenate dehydratase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. (267 aa) |
| | AFU03567.1 | COG0405 Gamma-glutamyltransferase. (643 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (403 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (382 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (482 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (373 aa) |
| | aroE | COG0169 Shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (268 aa) |
| | AFU03785.1 | Protein MetE; COG0620 Methionine synthase II (cobalamin-independent). (334 aa) |
| | glsA | COG2066 Glutaminase; Belongs to the glutaminase family. (621 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (296 aa) |
| | AFU03980.1 | COG1246 N-acetylglutamate synthase and related acetyltransferases. (152 aa) |
| | dapA-2 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (248 aa) |
| | AFU04027.1 | COG0665 Glycine/D-amino acid oxidases (deaminating). (310 aa) |
| | glnD | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (815 aa) |
| | AFU04205.1 | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. (112 aa) |
| | AFU04206.1 | Ammonium transporter; COG0004 Ammonia permease. (459 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (737 aa) |
| | AFU04300.1 | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (532 aa) |
| | AFU04385.1 | Phosphoserine phosphatase; COG3830 ACT domain-containing protein. (405 aa) |
| | AFU04411.1 | Putative methionine synthase; COG0280 Phosphotransacetylase. (367 aa) |
| | AFU04467.1 | Glutamine synthetase-like protein; COG0174 Glutamine synthetase. (450 aa) |
| | AFU04594.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (373 aa) |
| | AFU04729.1 | COG1171 Threonine dehydratase. (311 aa) |
| | AFU04762.1 | Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (417 aa) |
| | AFU04780.1 | Monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (261 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (418 aa) |
| | ahcY-2 | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (494 aa) |
| | AFU05119.1 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (367 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (302 aa) |
| | AFU05126.1 | COG0506 Proline dehydrogenase. (318 aa) |
| | AFU05127.1 | COG1012 NAD-dependent aldehyde dehydrogenases. (547 aa) |
| | phhB | COG2154 Pterin-4a-carbinolamine dehydratase. (98 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | AFU05239.1 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (381 aa) |
| | AFU05247.1 | Cystathionine beta-synthase; COG0031 Cysteine synthase. (458 aa) |
| | AFU05302.1 | COG0147 Anthranilate/para-aminobenzoate synthases component I. (427 aa) |
| | AFU05328.1 | Cystathionine beta-synthase; COG0031 Cysteine synthase. (344 aa) |
| | AFU05440.1 | Hypothetical protein; COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (202 aa) |
| | AFU05489.1 | Hypothetical protein; COG1605 Chorismate mutase. (97 aa) |
| | AFU05595.1 | COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. (408 aa) |
| | AFU05689.1 | Hypothetical protein; COG0031 Cysteine synthase. (343 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (291 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (296 aa) |
| | AFU05779.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (767 aa) |
| | AFU05884.1 | Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (381 aa) |
| | AFU05890.1 | Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (334 aa) |
| | AFU05896.1 | COG3508 Homogentisate 1,2-dioxygenase. (398 aa) |
| | AFU05897.1 | Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (401 aa) |
| | AFU06050.1 | COG1956 GAF domain-containing protein. (162 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | AFU06155.1 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (349 aa) |
