node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFT99200.1 | AFT99201.1 | O3I_006190 | O3I_006195 | COG0460 Homoserine dehydrogenase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.951 |
AFT99200.1 | AFT99673.1 | O3I_006190 | O3I_008555 | COG0460 Homoserine dehydrogenase. | COG1171 Threonine dehydratase. | 0.555 |
AFT99200.1 | AFU00679.1 | O3I_006190 | O3I_013590 | COG0460 Homoserine dehydrogenase. | COG1171 Threonine dehydratase. | 0.555 |
AFT99200.1 | AFU01093.1 | O3I_006190 | O3I_015660 | COG0460 Homoserine dehydrogenase. | Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. | 0.835 |
AFT99200.1 | AFU01647.1 | O3I_006190 | O3I_018440 | COG0460 Homoserine dehydrogenase. | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.841 |
AFT99200.1 | AFU02272.1 | O3I_006190 | O3I_021565 | COG0460 Homoserine dehydrogenase. | Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. | 0.884 |
AFT99200.1 | AFU04729.1 | O3I_006190 | O3I_033900 | COG0460 Homoserine dehydrogenase. | COG1171 Threonine dehydratase. | 0.555 |
AFT99200.1 | ilvA | O3I_006190 | O3I_011990 | COG0460 Homoserine dehydrogenase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.607 |
AFT99200.1 | thrB | O3I_006190 | O3I_006200 | COG0460 Homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
AFT99201.1 | AFT99200.1 | O3I_006195 | O3I_006190 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | COG0460 Homoserine dehydrogenase. | 0.951 |
AFT99201.1 | AFT99673.1 | O3I_006195 | O3I_008555 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | COG1171 Threonine dehydratase. | 0.940 |
AFT99201.1 | AFU00679.1 | O3I_006195 | O3I_013590 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | COG1171 Threonine dehydratase. | 0.943 |
AFT99201.1 | AFU01093.1 | O3I_006195 | O3I_015660 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. | 0.925 |
AFT99201.1 | AFU02272.1 | O3I_006195 | O3I_021565 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. | 0.927 |
AFT99201.1 | AFU04729.1 | O3I_006195 | O3I_033900 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | COG1171 Threonine dehydratase. | 0.940 |
AFT99201.1 | ilvA | O3I_006195 | O3I_011990 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.940 |
AFT99201.1 | thrB | O3I_006195 | O3I_006200 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.995 |
AFT99673.1 | AFT99200.1 | O3I_008555 | O3I_006190 | COG1171 Threonine dehydratase. | COG0460 Homoserine dehydrogenase. | 0.555 |
AFT99673.1 | AFT99201.1 | O3I_008555 | O3I_006195 | COG1171 Threonine dehydratase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.940 |
AFT99673.1 | AFU00679.1 | O3I_008555 | O3I_013590 | COG1171 Threonine dehydratase. | COG1171 Threonine dehydratase. | 0.846 |