STRINGSTRING
pimE pimE AFU00692.1 AFU00692.1 AFU00784.1 AFU00784.1 AFU00920.1 AFU00920.1 AFU00956.1 AFU00956.1 AFU00957.1 AFU00957.1 AFU00965.1 AFU00965.1 AFU00970.1 AFU00970.1 AFU00977.1 AFU00977.1 AFU00995.1 AFU00995.1 AFU00996.1 AFU00996.1 AFU01037.1 AFU01037.1 AFU01038.1 AFU01038.1 AFU01041.1 AFU01041.1 AFU01049.1 AFU01049.1 AFU01065.1 AFU01065.1 AFU01066.1 AFU01066.1 AFU01067.1 AFU01067.1 AFU01068.1 AFU01068.1 AFU01399.1 AFU01399.1 AFU01496.1 AFU01496.1 AFU05090.1 AFU05090.1 AFU01506.1 AFU01506.1 AFU01507.1 AFU01507.1 AFU01607.1 AFU01607.1 AFU01874.1 AFU01874.1 AFU02042.1 AFU02042.1 AFU02080.1 AFU02080.1 nobB nobB nobE nobE AFU02318.1 AFU02318.1 AFU02446.1 AFU02446.1 AFU02635.1 AFU02635.1 AFU03011.1 AFU03011.1 AFU03108.1 AFU03108.1 AFU03110.1 AFU03110.1 AFU03230.1 AFU03230.1 AFU03334.1 AFU03334.1 AFU03346.1 AFU03346.1 hisG hisG AFU03506.1 AFU03506.1 pyrR pyrR AFU03608.1 AFU03608.1 AFU06224.1 AFU06224.1 AFU06203.1 AFU06203.1 AFU06202.1 AFU06202.1 AFU06196.1 AFU06196.1 AFU06094.1 AFU06094.1 AFU05990.1 AFU05990.1 pyrE pyrE AFU05934.1 AFU05934.1 AFU05805.1 AFU05805.1 mshA mshA AFU05665.1 AFU05665.1 AFU05497.1 AFU05497.1 AFU05458.1 AFU05458.1 AFU05378.1 AFU05378.1 AFU05373.1 AFU05373.1 AFU05320.1 AFU05320.1 AFU05114.1 AFU05114.1 AFU05096.1 AFU05096.1 mltG mltG apt apt AFU03735.1 AFU03735.1 AFU03802.1 AFU03802.1 AFU03915.1 AFU03915.1 AFU03933.1 AFU03933.1 AFU03963.1 AFU03963.1 AFU04103.1 AFU04103.1 AFU04239.1 AFU04239.1 AFU04364.1 AFU04364.1 AFU04398.1 AFU04398.1 AFU04399.1 AFU04399.1 AFU04414.1 AFU04414.1 AFU04487.1 AFU04487.1 AFU04792.1 AFU04792.1 AFU04964.1 AFU04964.1 AFU05089.1 AFU05089.1 AFT97993.1 AFT97993.1 AFT98100.1 AFT98100.1 AFT98103.1 AFT98103.1 AFT98116.1 AFT98116.1 AFT98119.1 AFT98119.1 AFT98121.1 AFT98121.1 AFT98141.1 AFT98141.1 tgt tgt AFT98312.1 AFT98312.1 AFT98392.1 AFT98392.1 AFT98565.1 AFT98565.1 AFT98597.1 AFT98597.1 purF purF AFT98655.1 AFT98655.1 mtnP mtnP deoA deoA upp upp AFT99055.1 AFT99055.1 AFT99097.1 AFT99097.1 AFT99107.1 AFT99107.1 AFT99208.1 AFT99208.1 glgB glgB glgE glgE AFT99240.1 AFT99240.1 AFT99252.1 AFT99252.1 AFT99426.1 AFT99426.1 AFT99449.1 AFT99449.1 ppnP ppnP AFU00200.1 AFU00200.1 AFU00201.1 AFU00201.1 cobT cobT AFU00251.1 AFU00251.1 trpD trpD AFU00271.1 AFU00271.1 AFU00305.1 AFU00305.1 murG murG AFU00310.1 AFU00310.1 AFU00323.1 AFU00323.1 AFU00351.1 AFU00351.1 AFU00403.1 AFU00403.1 hisH hisH hisF hisF lgt lgt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pimEMannosyltransferase. (396 aa)
AFU00692.1Mannosyltransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis. (374 aa)
AFU00784.1COG0463 Glycosyltransferases involved in cell wall biogenesis. (320 aa)
AFU00920.1Hypothetical protein. (552 aa)
AFU00956.1D-inositol 3-phosphate glycosyltransferase; COG0438 Glycosyltransferase. (366 aa)
AFU00957.1COG0438 Glycosyltransferase. (383 aa)
AFU00965.1COG0438 Glycosyltransferase. (385 aa)
AFU00970.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (403 aa)
AFU00977.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (385 aa)
AFU00995.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (387 aa)
AFU00996.1Putative cytoplasmic protein; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (393 aa)
AFU01037.1Hypothetical protein. (448 aa)
AFU01038.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (414 aa)
AFU01041.1Hypothetical protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins. (448 aa)
AFU01049.1Hypothetical protein. (457 aa)
AFU01065.1Hypothetical protein. (333 aa)
AFU01066.1COG0438 Glycosyltransferase. (371 aa)
AFU01067.1Hypothetical protein; COG0438 Glycosyltransferase. (364 aa)
AFU01068.1Hypothetical protein. (542 aa)
AFU01399.1COG2236 Predicted phosphoribosyltransferases. (164 aa)
AFU01496.1COG0438 Glycosyltransferase. (369 aa)
AFU05090.1Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. (261 aa)
AFU01506.1COG0438 Glycosyltransferase. (393 aa)
AFU01507.1D-inositol 3-phosphate glycosyltransferase; COG0438 Glycosyltransferase. (356 aa)
AFU01607.1Beta-phosphoglucomutase family hydrolase; COG0637 Predicted phosphatase/phosphohexomutase. (1062 aa)
AFU01874.1Hypothetical protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (281 aa)
AFU02042.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (409 aa)
AFU02080.1COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase. (502 aa)
nobBMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (292 aa)
nobEAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (191 aa)
AFU02318.1Glycosidase; COG1554 Trehalose and maltose hydrolases (possible phosphorylases). (781 aa)
AFU02446.1Rifampin glycosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (413 aa)
AFU02635.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (440 aa)
AFU03011.1Hypothetical protein. (305 aa)
AFU03108.1COG0438 Glycosyltransferase. (403 aa)
AFU03110.1Glycosyltransferase; COG0859 ADP-heptose:LPS heptosyltransferase. (324 aa)
AFU03230.1Glycosyltransferase; COG0859 ADP-heptose:LPS heptosyltransferase. (329 aa)
AFU03334.1Hypothetical protein. (511 aa)
AFU03346.1Hypothetical protein. (496 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa)
AFU03506.1Putative transporter. (560 aa)
pyrRBifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (211 aa)
AFU03608.1Hypothetical protein. (226 aa)
AFU06224.1COG5650 Predicted integral membrane protein. (468 aa)
AFU06203.1Hypothetical protein; COG5650 Predicted integral membrane protein. (612 aa)
AFU06202.1COG0744 Membrane carboxypeptidase (penicillin-binding protein). (805 aa)
AFU06196.1Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein). (752 aa)
AFU06094.1COG0438 Glycosyltransferase. (390 aa)
AFU05990.1Hypothetical protein. (374 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (193 aa)
AFU05934.1Putative Glycosyl transferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family. (668 aa)
AFU05805.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (425 aa)
mshAGlycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (465 aa)
AFU05665.1COG0438 Glycosyltransferase. (380 aa)
AFU05497.1Hypothetical protein. (415 aa)
AFU05458.1Hypothetical protein. (74 aa)
AFU05378.1COG0438 Glycosyltransferase. (355 aa)
AFU05373.1COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase. (541 aa)
AFU05320.1Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. (258 aa)
AFU05114.1Glucosyl-3-phosphoglycerate synthase; COG0463 Glycosyltransferases involved in cell wall biogenesis. (317 aa)
AFU05096.1COG0438 Glycosyltransferase. (408 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (473 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (190 aa)
AFU03735.1Phosphatidylinositol alpha-mannosyltransferase; COG0438 Glycosyltransferase. (374 aa)
AFU03802.1Hypothetical protein. (438 aa)
AFU03915.1Putative mannosyltransferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family. (665 aa)
AFU03933.1Putative mannosyltransferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family. (662 aa)
AFU03963.1Hypothetical protein; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (387 aa)
AFU04103.1COG0438 Glycosyltransferase. (122 aa)
AFU04239.1COG0463 Glycosyltransferases involved in cell wall biogenesis. (213 aa)
AFU04364.1COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (461 aa)
AFU04398.1COG0438 Glycosyltransferase. (417 aa)
AFU04399.1Hypothetical protein; Belongs to the glycosyl hydrolase 57 family. (534 aa)
AFU04414.1S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (342 aa)
AFU04487.1Glycoside hydrolase; COG1554 Trehalose and maltose hydrolases (possible phosphorylases). (898 aa)
AFU04792.1Hypothetical protein. (476 aa)
AFU04964.1Hypothetical protein; COG1040 Predicted amidophosphoribosyltransferases. (213 aa)
AFU05089.1Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. (414 aa)
AFT97993.1COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family. (463 aa)
AFT98100.1Galactofuranosyltransferase; COG1216 Predicted glycosyltransferases. (640 aa)
AFT98103.1Hypothetical protein. (647 aa)
AFT98116.1Arabinosyltransferase. (1115 aa)
AFT98119.1Arabinosyltransferase. (1131 aa)
AFT98121.1Arabinofuranosyl transferase A. (668 aa)
AFT98141.1COG1216 Predicted glycosyltransferases. (661 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (414 aa)
AFT98312.1Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein). (789 aa)
AFT98392.1COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa)
AFT98565.1COG0380 Trehalose-6-phosphate synthase. (520 aa)
AFT98597.1Hypothetical protein. (441 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (526 aa)
AFT98655.1COG0463 Glycosyltransferases involved in cell wall biogenesis. (233 aa)
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (269 aa)
deoACOG0213 Thymidine phosphorylase. (429 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
AFT99055.1COG0005 Purine nucleoside phosphorylase. (259 aa)
AFT99097.1COG0463 Glycosyltransferases involved in cell wall biogenesis. (339 aa)
AFT99107.1Hypothetical protein. (462 aa)
AFT99208.1Undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (385 aa)
glgBGlycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (712 aa)
glgEAlpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (666 aa)
AFT99240.1COG0058 Glucan phosphorylase. (862 aa)
AFT99252.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (450 aa)
AFT99426.1Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. (552 aa)
AFT99449.1Glycosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase. (391 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (93 aa)
AFU00200.1Hypothetical protein. (309 aa)
AFU00201.1COG0438 Glycosyltransferase. (366 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (367 aa)
AFU00251.1COG0438 Glycosyltransferase. (375 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa)
AFU00271.1Hypothetical protein. (555 aa)
AFU00305.1COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family. (487 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (365 aa)
AFU00310.1Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (230 aa)
AFU00323.1Arabinosyltransferase C. (1095 aa)
AFU00351.1COG0438 Glycosyltransferase. (338 aa)
AFU00403.1COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (286 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (444 aa)
Your Current Organism:
Nocardia brasiliensis
NCBI taxonomy Id: 1133849
Other names: N. brasiliensis ATCC 700358, Nocardia brasiliensis ATCC 700358, Nocardia brasiliensis HUJEG-1, Nocardia brasiliensis str. ATCC 700358, Nocardia brasiliensis strain ATCC 700358
Server load: low (20%) [HD]