STRINGSTRING
AFT97985.1 AFT97985.1 AFT98002.1 AFT98002.1 AFT98012.1 AFT98012.1 AFT98023.1 AFT98023.1 pheA pheA AFT98137.1 AFT98137.1 AFT98219.1 AFT98219.1 AFT98227.1 AFT98227.1 AFT98282.1 AFT98282.1 nth nth AFT98379.1 AFT98379.1 AFT98408.1 AFT98408.1 panD panD AFT98448.1 AFT98448.1 ispF ispF AFT98459.1 AFT98459.1 AFT98469.1 AFT98469.1 AFT98470.1 AFT98470.1 AFT98483.1 AFT98483.1 AFT98486.1 AFT98486.1 AFT98488.1 AFT98488.1 AFT98516.1 AFT98516.1 AFT98526.1 AFT98526.1 AFT98527.1 AFT98527.1 AFT98528.1 AFT98528.1 AFT98541.1 AFT98541.1 AFT98546.1 AFT98546.1 AFT98575.1 AFT98575.1 AFT98587.1 AFT98587.1 AFT98644.1 AFT98644.1 AFT98660.1 AFT98660.1 AFT98720.1 AFT98720.1 AFT98737.1 AFT98737.1 AFT98740.1 AFT98740.1 AFT98784.1 AFT98784.1 nnrD nnrD AFT99001.1 AFT99001.1 AFT99013.1 AFT99013.1 AFT99059.1 AFT99059.1 AFT99073.1 AFT99073.1 purK purK AFT99185.1 AFT99185.1 lysA lysA AFT99201.1 AFT99201.1 AFT99258.1 AFT99258.1 AFT99374.1 AFT99374.1 AFT99390.1 AFT99390.1 AFT99450.1 AFT99450.1 AFT99461.1 AFT99461.1 AFT99537.1 AFT99537.1 AFT99546.1 AFT99546.1 AFT99549.1 AFT99549.1 AFT99571.1 AFT99571.1 lysA-2 lysA-2 AFT99583.1 AFT99583.1 AFT99614.1 AFT99614.1 AFT99662.1 AFT99662.1 AFT99669.1 AFT99669.1 AFT99673.1 AFT99673.1 AFT99705.1 AFT99705.1 AFT99721.1 AFT99721.1 AFT99737.1 AFT99737.1 AFT99857.1 AFT99857.1 AFT99860.1 AFT99860.1 AFT99969.1 AFT99969.1 AFT99980.1 AFT99980.1 AFU00052.1 AFU00052.1 AFU00095.1 AFU00095.1 leuD leuD leuC leuC AFU00121.1 AFU00121.1 AFU00151.1 AFU00151.1 cobD cobD AFU00292.1 AFU00292.1 AFU00317.1 AFU00317.1 ilvA ilvA hisB hisB hisH hisH hisF hisF trpE trpE trpC trpC trpB trpB trpA trpA AFU00459.1 AFU00459.1 AFU00488.1 AFU00488.1 AFU00517.1 AFU00517.1 AFU00544.1 AFU00544.1 ppc ppc AFU00608.1 AFU00608.1 AFU00610.1 AFU00610.1 AFU00619.1 AFU00619.1 argH argH AFU00679.1 AFU00679.1 AFU00809.1 AFU00809.1 AFU00844.1 AFU00844.1 ilvD ilvD AFU00889.1 AFU00889.1 AFU00913.1 AFU00913.1 AFU00981.1 AFU00981.1 AFU00992.1 AFU00992.1 AFU00999.1 AFU00999.1 AFU01011.1 AFU01011.1 AFU01093.1 AFU01093.1 dapA dapA AFU01195.1 AFU01195.1 AFU01207.1 AFU01207.1 AFU01277.1 AFU01277.1 AFU01302.1 AFU01302.1 hutU hutU AFU01317.1 AFU01317.1 AFU01325.1 AFU01325.1 AFU01410.1 AFU01410.1 AFU01461.1 AFU01461.1 AFU01468.1 AFU01468.1 AFU01477.1 AFU01477.1 pckG pckG AFU01647.1 AFU01647.1 AFU01781.1 AFU01781.1 AFU01825.1 AFU01825.1 AFU01882.1 AFU01882.1 AFU01906.1 AFU01906.1 AFU01938.1 AFU01938.1 AFU02146.1 AFU02146.1 AFU02179.1 AFU02179.1 AFU02201.1 AFU02201.1 AFU02239.1 AFU02239.1 AFU02255.1 AFU02255.1 AFU02272.1 AFU02272.1 AFU02307.1 AFU02307.1 AFU02308.1 AFU02308.1 AFU02309.1 AFU02309.1 AFU02310.1 AFU02310.1 AFU02314.1 AFU02314.1 AFU02334.1 AFU02334.1 AFU02433.1 AFU02433.1 AFU02434.1 AFU02434.1 AFU02445.1 AFU02445.1 AFU02525.1 AFU02525.1 AFU02623.1 AFU02623.1 AFU02656.1 AFU02656.1 AFU02679.1 AFU02679.1 AFU02751.1 AFU02751.1 AFU02824.1 AFU02824.1 AFU02829.1 AFU02829.1 AFU03020.1 AFU03020.1 ectC ectC AFU03190.1 AFU03190.1 AFU03195.1 AFU03195.1 AFU03237.1 AFU03237.1 AFU03262.1 AFU03262.1 AFU03376.1 AFU03376.1 hemH hemH AFU03465.1 AFU03465.1 ribBA ribBA AFU03592.1 AFU03592.1 pyrF pyrF aroC aroC aroB aroB mltG mltG pdxT pdxT pdxS pdxS AFU03742.1 AFU03742.1 AFU03743.1 AFU03743.1 AFU03752.1 AFU03752.1 hemE hemE AFU03828.1 AFU03828.1 AFU03889.1 AFU03889.1 speE speE AFU03894.1 AFU03894.1 dapA-2 dapA-2 AFU04167.1 AFU04167.1 mutM mutM AFU04271.1 AFU04271.1 leuD-2 leuD-2 leuC-2 leuC-2 ilvD-2 ilvD-2 AFU04383.1 AFU04383.1 AFU04391.1 AFU04391.1 moaA moaA moaC moaC murQ murQ AFU04510.1 AFU04510.1 AFU04512.1 AFU04512.1 AFU04586.1 AFU04586.1 AFU04597.1 AFU04597.1 AFU04621.1 AFU04621.1 AFU04622.1 AFU04622.1 AFU04676.1 AFU04676.1 AFU04729.1 AFU04729.1 AFU04758.1 AFU04758.1 AFU04808.1 AFU04808.1 AFU04846.1 AFU04846.1 AFU04857.1 AFU04857.1 mtnA mtnA AFU04910.1 AFU04910.1 AFU04911.1 AFU04911.1 AFU05009.1 AFU05009.1 AFU05045.1 AFU05045.1 AFU05049.1 AFU05049.1 kgd kgd AFU05079.1 AFU05079.1 AFU05086.1 AFU05086.1 fbiC fbiC phhB phhB AFU05171.1 AFU05171.1 fumC fumC AFU05220.1 AFU05220.1 AFU05302.1 AFU05302.1 eno eno AFU05327.1 AFU05327.1 AFU05427.1 AFU05427.1 AFU05496.1 AFU05496.1 AFU05543.1 AFU05543.1 AFU05544.1 AFU05544.1 AFU05562.1 AFU05562.1 menB menB AFU05689.1 AFU05689.1 AFU05710.1 AFU05710.1 AFU05714.1 AFU05714.1 deoC deoC AFU05781.1 AFU05781.1 AFU05786.1 AFU05786.1 AFU05796.1 AFU05796.1 AFU05824.1 AFU05824.1 psd psd thiC thiC AFU05910.1 AFU05910.1 AFU05944.1 AFU05944.1 AFU05946.1 AFU05946.1 AFU05977.1 AFU05977.1 pckG-2 pckG-2 AFU06120.1 AFU06120.1 aroQ aroQ menC menC AFU06215.1 AFU06215.1 AFU06286.1 AFU06286.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFT97985.1COG0512 Anthranilate/para-aminobenzoate synthases component II. (214 aa)
AFT98002.1Hypothetical protein. (470 aa)
AFT98012.1COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (516 aa)
AFT98023.1Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (162 aa)
pheACOG0077 Prephenate dehydratase. (304 aa)
AFT98137.1COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (333 aa)
AFT98219.1Hypothetical protein. (207 aa)
AFT98227.1Base excision DNA repair protein; COG0177 Predicted EndoIII-related endonuclease. (190 aa)
AFT98282.1Hypothetical protein. (137 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (277 aa)
AFT98379.1OHCU decarboxylase. (106 aa)
AFT98408.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (145 aa)
panDAspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (140 aa)
AFT98448.1COG0288 Carbonic anhydrase. (207 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
AFT98459.1enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase. (269 aa)
AFT98469.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (312 aa)
AFT98470.1Hypothetical protein; COG2030 Acyl dehydratase. (138 aa)
AFT98483.1Putative 3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; COG2030 Acyl dehydratase. (287 aa)
AFT98486.1COG3971 2-keto-4-pentenoate hydratase. (261 aa)
AFT98488.14-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (345 aa)
AFT98516.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (292 aa)
AFT98526.1CoA-transferase subunit beta; COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (261 aa)
AFT98527.1CoA-transferase subunit alpha; COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (289 aa)
AFT98528.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (254 aa)
AFT98541.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (308 aa)
AFT98546.1Hypothetical protein; COG3607 Predicted lactoylglutathione lyase. (138 aa)
AFT98575.1COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (473 aa)
AFT98587.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (467 aa)
AFT98644.1Hypothetical protein; COG2030 Acyl dehydratase. (294 aa)
AFT98660.1Salicylate synthase MbtI; COG0147 Anthranilate/para-aminobenzoate synthases component I. (437 aa)
AFT98720.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (232 aa)
AFT98737.1COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (335 aa)
AFT98740.1SARP family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (1084 aa)
AFT98784.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (273 aa)
nnrDPutative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] (482 aa)
AFT99001.1COG2873 O-acetylhomoserine sulfhydrylase. (442 aa)
AFT99013.1COG2030 Acyl dehydratase. (292 aa)
AFT99059.1Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (157 aa)
AFT99073.1DNA glycosylase; COG0266 Formamidopyrimidine-DNA glycosylase. (260 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (390 aa)
AFT99185.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (474 aa)
AFT99201.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa)
AFT99258.1COG0031 Cysteine synthase. (320 aa)
AFT99374.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (463 aa)
AFT99390.1Hypothetical protein. (153 aa)
AFT99450.1Polyketide synthesis cyclase. (108 aa)
AFT99461.1NDP-hexose 23-dehydratase. (460 aa)
AFT99537.1Hypothetical protein. (362 aa)
AFT99546.1COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (427 aa)
AFT99549.1COG3407 Mevalonate pyrophosphate decarboxylase. (339 aa)
AFT99571.1COG0019 Diaminopimelate decarboxylase. (423 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (447 aa)
AFT99583.1Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. (214 aa)
AFT99614.1Hypothetical protein; COG0144 tRNA and rRNA cytosine-C5-methylases. (179 aa)
AFT99662.1Antigen Cfp30B; COG3324 Predicted enzyme related to lactoylglutathione lyase. (283 aa)
AFT99669.1Terpene synthase metal-binding domain-containing protein. (321 aa)
AFT99673.1COG1171 Threonine dehydratase. (322 aa)
AFT99705.1DNA glycosylase; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (270 aa)
AFT99721.1COG3957 Phosphoketolase. (822 aa)
AFT99737.1COG2873 O-acetylhomoserine sulfhydrylase. (437 aa)
AFT99857.1Putative dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (136 aa)
AFT99860.1Hypothetical protein. (249 aa)
AFT99969.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (339 aa)
AFT99980.1MaoC domain-containing protein dehydratase; COG2030 Acyl dehydratase. (152 aa)
AFU00052.1COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family. (591 aa)
AFU00095.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (262 aa)
leuDIsopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (207 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa)
AFU00121.1COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. (313 aa)
AFU00151.1Hypothetical protein; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily. (171 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (297 aa)
AFU00292.1COG2324 Predicted membrane protein. (326 aa)
AFU00317.1Hypothetical protein. (138 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (451 aa)
hisBCOG0131 Imidazoleglycerol-phosphate dehydratase. (205 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (519 aa)
trpCCOG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (272 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa)
AFU00459.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (131 aa)
AFU00488.1Hypothetical protein. (197 aa)
AFU00517.1COG0288 Carbonic anhydrase. (164 aa)
AFU00544.1COG0019 Diaminopimelate decarboxylase. (449 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (923 aa)
AFU00608.1Hypothetical protein; COG3616 Predicted amino acid aldolase or racemase. (441 aa)
AFU00610.14-hydroxy-2-oxoglutarate/2-dehydro-3- deoxy-phosphogluconate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (209 aa)
AFU00619.1PEP phosphonomutase-like protein. (223 aa)
argHCOG0165 Argininosuccinate lyase. (473 aa)
AFU00679.1COG1171 Threonine dehydratase. (411 aa)
AFU00809.1Terpene synthase metal-binding domain-containing protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases. (755 aa)
AFU00844.1COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (303 aa)
ilvDCOG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (568 aa)
AFU00889.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (257 aa)
AFU00913.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (203 aa)
AFU00981.1Polyketide synthesis cyclase. (107 aa)
AFU00992.1Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (318 aa)
AFU00999.1methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (145 aa)
AFU01011.1NDP-hexose 2,3-dehydratase. (479 aa)
AFU01093.1Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. (382 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (315 aa)
AFU01195.1OHCU decarboxylase; COG3195 Uncharacterized protein conserved in bacteria. (170 aa)
AFU01207.1COG3960 Glyoxylate carboligase. (434 aa)
AFU01277.1Beta-ketoacyl synthase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases. (673 aa)
AFU01302.1COG2986 Histidine ammonia-lyase. (515 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (550 aa)
AFU01317.1Hypothetical protein; COG0015 Adenylosuccinate lyase. (1114 aa)
AFU01325.1Hypothetical protein; COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (265 aa)
AFU01410.1oxidoreductase/HEAT repeat-containing protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (895 aa)
AFU01461.1Mandelate racemase/muconate lactonizing enzyme protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (454 aa)
AFU01468.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (283 aa)
AFU01477.1ATPase-like protein; COG3899 Predicted ATPase. (1037 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
AFU01647.1COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
AFU01781.1COG1982 Arginine/lysine/ornithine decarboxylases. (485 aa)
AFU01825.1Hypothetical protein; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (465 aa)
AFU01882.1COG3338 Carbonic anhydrase. (260 aa)
AFU01906.1Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (295 aa)
AFU01938.1COG0019 Diaminopimelate decarboxylase. (495 aa)
AFU02146.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (134 aa)
AFU02179.1Aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (387 aa)
AFU02201.1Putative hydroxylase/glyoxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (256 aa)
AFU02239.1Phosphonopyruvate decarboxylase; COG4032 Predicted thiamine-pyrophosphate-binding protein. (383 aa)
AFU02255.1Hypothetical protein. (148 aa)
AFU02272.1Pyridoxal-5'-phosphate-dependent protein subunit beta; COG0498 Threonine synthase. (396 aa)
AFU02307.1Hypothetical protein; COG5485 Predicted ester cyclase. (180 aa)
AFU02308.14-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (127 aa)
AFU02309.13-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (258 aa)
AFU02310.13-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. (448 aa)
AFU02314.1COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (271 aa)
AFU02334.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (131 aa)
AFU02433.1Hydratase; COG3971 2-keto-4-pentenoate hydratase. (261 aa)
AFU02434.1COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. (271 aa)
AFU02445.1COG2986 Histidine ammonia-lyase. (523 aa)
AFU02525.1Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (295 aa)
AFU02623.1COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (138 aa)
AFU02656.1COG0720 6-pyruvoyl-tetrahydropterin synthase. (117 aa)
AFU02679.1COG1171 Threonine dehydratase. (325 aa)
AFU02751.1Terpene synthase metal-binding domain-containing protein. (352 aa)
AFU02824.1COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (297 aa)
AFU02829.1COG1088 dTDP-D-glucose 4,6-dehydratase. (314 aa)
AFU03020.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (283 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (132 aa)
AFU03190.1Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases. (162 aa)
AFU03195.1Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases. (154 aa)
AFU03237.1Hypothetical protein; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase. (163 aa)
AFU03262.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (264 aa)
AFU03376.1Sulfopyruvate decarboxylase subunit alpha; COG4032 Predicted thiamine-pyrophosphate-binding protein. (180 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (353 aa)
AFU03465.1Aconitate hydratase; COG1048 Aconitase A. (939 aa)
ribBABifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (414 aa)
AFU03592.1Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)
pyrFCOG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (274 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (382 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (373 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (473 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (215 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (300 aa)
AFU03742.1Transporter; COG0659 Sulfate permease and related transporters (MFS superfamily). (725 aa)
AFU03743.1Transporter; COG0659 Sulfate permease and related transporters (MFS superfamily). (743 aa)
AFU03752.1Carnitine operon protein CaiE; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily. (180 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (351 aa)
AFU03828.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
AFU03889.1COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (370 aa)
speES-adenosylmethionine decarboxylase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (400 aa)
AFU03894.1AIG2 family protein. (157 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa)
AFU04167.1Hypothetical protein; COG4689 Acetoacetate decarboxylase. (229 aa)
mutMFormamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa)
AFU04271.1enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase. (259 aa)
leuD-2Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa)
leuC-2Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa)
ilvD-2COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (613 aa)
AFU04383.1Hypothetical protein; COG3324 Predicted enzyme related to lactoylglutathione lyase. (268 aa)
AFU04391.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (258 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (342 aa)
moaCBifunctional molybdenum cofactor biosynthesis protein MoaC/MogA; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (333 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (300 aa)
AFU04510.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
AFU04512.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (243 aa)
AFU04586.1Putative intramolecular lyase; COG0015 Adenylosuccinate lyase. (457 aa)
AFU04597.1COG3407 Mevalonate pyrophosphate decarboxylase. (350 aa)
AFU04621.12-methylcitrate dehydratase; COG2079 Uncharacterized protein involved in propionate catabolism. (500 aa)
AFU04622.12-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (304 aa)
AFU04676.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (234 aa)
AFU04729.1COG1171 Threonine dehydratase. (311 aa)
AFU04758.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (474 aa)
AFU04808.1Putative pyruvoyl-dependent arginine decarboxylase. (160 aa)
AFU04846.1Deoxyribodipyrimidine photo-lyase (DNA photolyase) (Photoreactivating enzyme); COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (441 aa)
AFU04857.1Putative antigen; COG3324 Predicted enzyme related to lactoylglutathione lyase. (287 aa)
mtnAInitiation factor eIF-2B subunit alpha-like protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the aldolase class II family. (551 aa)
AFU04910.1Hypothetical protein. (268 aa)
AFU04911.1Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase. (418 aa)
AFU05009.1Hypothetical protein. (798 aa)
AFU05045.1Hypothetical protein; COG3616 Predicted amino acid aldolase or racemase. (392 aa)
AFU05049.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (264 aa)
kgdAlpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1249 aa)
AFU05079.1Malate dehydrogenase; COG0281 Malic enzyme. (366 aa)
AFU05086.1COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (320 aa)
fbiCFO synthase; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (846 aa)
phhBCOG2154 Pterin-4a-carbinolamine dehydratase. (98 aa)
AFU05171.1Hypothetical protein; COG3161 4-hydroxybenzoate synthetase (chorismate lyase). (186 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
AFU05220.1Hypothetical protein; COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (548 aa)
AFU05302.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (427 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
AFU05327.1Putative diaminopimelate decarboxylase (DAP decarboxylase); COG0019 Diaminopimelate decarboxylase. (446 aa)
AFU05427.1Hypothetical protein. (928 aa)
AFU05496.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (253 aa)
AFU05543.1Putative dehydratase protein, MaoC domain protein; COG2030 Acyl dehydratase. (166 aa)
AFU05544.1COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (270 aa)
AFU05562.1COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (273 aa)
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (297 aa)
AFU05689.1Hypothetical protein; COG0031 Cysteine synthase. (343 aa)
AFU05710.1COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (322 aa)
AFU05714.1uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase. (521 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (208 aa)
AFU05781.1COG2224 Isocitrate lyase. (429 aa)
AFU05786.1Hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (395 aa)
AFU05796.1Putative OHCU decarboxylase; COG3195 Uncharacterized protein conserved in bacteria. (167 aa)
AFU05824.1Fructose-bisphosphate aldolase, class II; COG0191 Fructose/tagatose bisphosphate aldolase. (274 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (244 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (537 aa)
AFU05910.1Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (283 aa)
AFU05944.1Hypothetical protein. (570 aa)
AFU05946.1COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (307 aa)
AFU05977.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
pckG-2Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
AFU06120.1Hypothetical protein; COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (518 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (325 aa)
AFU06215.1Hypothetical protein; COG2301 Citrate lyase beta subunit. (404 aa)
AFU06286.1Hypothetical protein; COG3899 Predicted ATPase. (393 aa)
Your Current Organism:
Nocardia brasiliensis
NCBI taxonomy Id: 1133849
Other names: N. brasiliensis ATCC 700358, Nocardia brasiliensis ATCC 700358, Nocardia brasiliensis HUJEG-1, Nocardia brasiliensis str. ATCC 700358, Nocardia brasiliensis strain ATCC 700358
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