(32 nodes) Artery morphogenesis network (Scleropages formosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	angptl3	Angiopoietin-related protein 3-like. (461 aa)
	apob	Apolipoprotein B-100-like. (4397 aa)
	LOC108929131	PR domain zinc finger protein 1-like. (705 aa)
	LOC108937135	Angiomotin-like 2a-like. (725 aa)
	prdm1	PR domain zinc finger protein 1-like. (784 aa)
	LOC108919973	Hydroxyprostaglandin dehydrogenase 15-(NAD)-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (362 aa)
	GJA5-2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (370 aa)
	LOC108919682	Peptidylprolyl isomerase. (590 aa)
	LOC108935068	Angiopoietin-related protein 3-like. (465 aa)
	Z043_122970	Putative G-protein coupled receptor 116; Belongs to the G-protein coupled receptor 2 family. (489 aa)
	EDNRA	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (479 aa)
	LOC108920640	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1118 aa)
	LOC108921768	Angiomotin-like 2a-like. (706 aa)
	hpgd	Uncharacterized protein. (261 aa)
	edn1	Endothelin-1. (116 aa)
	Z043_110323	Uncharacterized protein. (700 aa)
	nprl3	Uncharacterized protein. (614 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1075 aa)
	LOC108933568	Uncharacterized protein. (604 aa)
	FKBP10	Peptidylprolyl isomerase. (588 aa)
	vegfa	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (184 aa)
	EDNRA-2	G_PROTEIN_RECEP_F1_2 domain-containing protein. (434 aa)
	Nf1	Ras-GAP domain-containing protein. (2790 aa)
	LOC108927085	Serum response factor-like. (578 aa)
	hey2	Hairy/enhancer-of-split related with YRPW motif protein 2-like. (334 aa)
	ENSSFOP00015064735	annotation not available (151 aa)
	LOC108935074	T-cell acute lymphocytic leukemia protein 1-like. (342 aa)
	LOC108928606	Calcitonin gene-related peptide type 1 receptor-like; Belongs to the G-protein coupled receptor 2 family. (517 aa)
	arid2	AT-rich interactive domain-containing protein 2-like. (1733 aa)
	Z043_109457	Vascular endothelial growth factor A-A-like; Belongs to the PDGF/VEGF growth factor family. (194 aa)
	calcrl	Calcitonin gene-related peptide type 1 receptor-like; Belongs to the G-protein coupled receptor 2 family. (469 aa)

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRA	EDNRA-2	ENSSFOP00015025410	ENSSFOP00015059180	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.902
EDNRA	ENSSFOP00015064735	ENSSFOP00015025410	ENSSFOP00015064735	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	annotation not available	0.916
EDNRA	edn1	ENSSFOP00015025410	ENSSFOP00015031204	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1.	0.991
EDNRA-2	EDNRA	ENSSFOP00015059180	ENSSFOP00015025410	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.902
EDNRA-2	ENSSFOP00015064735	ENSSFOP00015059180	ENSSFOP00015064735	G_PROTEIN_RECEP_F1_2 domain-containing protein.	annotation not available	0.916
EDNRA-2	edn1	ENSSFOP00015059180	ENSSFOP00015031204	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin-1.	0.991
ENSSFOP00015064735	EDNRA	ENSSFOP00015064735	ENSSFOP00015025410	annotation not available	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.916
ENSSFOP00015064735	EDNRA-2	ENSSFOP00015064735	ENSSFOP00015059180	annotation not available	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.916
LOC108920640	bmpr2	ENSSFOP00015028246	ENSSFOP00015038606	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
LOC108927085	LOC108933568	ENSSFOP00015062466	ENSSFOP00015040522	Serum response factor-like.	Uncharacterized protein.	0.901
LOC108928606	calcrl	ENSSFOP00015070561	ENSSFOP00015079309	Calcitonin gene-related peptide type 1 receptor-like; Belongs to the G-protein coupled receptor 2 family.	Calcitonin gene-related peptide type 1 receptor-like; Belongs to the G-protein coupled receptor 2 family.	0.901
LOC108933568	LOC108927085	ENSSFOP00015040522	ENSSFOP00015062466	Uncharacterized protein.	Serum response factor-like.	0.901
LOC108935068	apob	ENSSFOP00015020591	ENSSFOP00015005020	Angiopoietin-related protein 3-like.	Apolipoprotein B-100-like.	0.510
angptl3	apob	ENSSFOP00015001393	ENSSFOP00015005020	Angiopoietin-related protein 3-like.	Apolipoprotein B-100-like.	0.510
apob	LOC108935068	ENSSFOP00015005020	ENSSFOP00015020591	Apolipoprotein B-100-like.	Angiopoietin-related protein 3-like.	0.510
apob	angptl3	ENSSFOP00015005020	ENSSFOP00015001393	Apolipoprotein B-100-like.	Angiopoietin-related protein 3-like.	0.510
bmpr2	LOC108920640	ENSSFOP00015038606	ENSSFOP00015028246	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
calcrl	LOC108928606	ENSSFOP00015079309	ENSSFOP00015070561	Calcitonin gene-related peptide type 1 receptor-like; Belongs to the G-protein coupled receptor 2 family.	Calcitonin gene-related peptide type 1 receptor-like; Belongs to the G-protein coupled receptor 2 family.	0.901
edn1	EDNRA	ENSSFOP00015031204	ENSSFOP00015025410	Endothelin-1.	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.991
edn1	EDNRA-2	ENSSFOP00015031204	ENSSFOP00015059180	Endothelin-1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.991