(94 nodes) Negative regulation of neurogenesis network (Scleropages formosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sema3a	Semaphorin-3A-like; Belongs to the semaphorin family. (789 aa)
	ENSSFOP00015058220	Semaphorin-6B-like. (856 aa)
	LOC108927221	BMP/retinoic acid-inducible neural-specific protein 1-like. (761 aa)
	SEMA4D-2	Semaphorin-4D-like; Belongs to the semaphorin family. (843 aa)
	ski	Uncharacterized protein. (712 aa)
	LOC108927702	Disco-interacting protein 2C-like. (1604 aa)
	Z043_104341	Neurogenic locus notch protein-like. (2445 aa)
	Z043_120547	Uncharacterized protein. (980 aa)
	LOC108937019	Semaphorin-3F-like; Belongs to the semaphorin family. (795 aa)
	SEMA4F	Semaphorin-4F-like; Belongs to the semaphorin family. (795 aa)
	Z043_120034	Disco-interacting protein 2A-like. (1586 aa)
	LOC108936518	Semaphorin-3E-like; Belongs to the semaphorin family. (780 aa)
	LOC108921276	Merlin-like. (594 aa)
	tnr	Tenascin-R-like. (1369 aa)
	sema3c	Semaphorin-3C-like; Belongs to the semaphorin family. (792 aa)
	Z043_101754	Semaphorin-3D-like; Belongs to the semaphorin family. (870 aa)
	Z043_120019	Uncharacterized protein. (226 aa)
	LOC108941907	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6E-like; Belongs to the semaphorin family. (1065 aa)
	sema3f	Semaphorin-3F-like; Belongs to the semaphorin family. (798 aa)
	ulk2	Serine/threonine-protein kinase ULK2-like. (1043 aa)
	ifrd1	Interferon-related developmental regulator 1-like. (441 aa)
	LOC108942045	Semaphorin-6D-like; Belongs to the semaphorin family. (1083 aa)
	LOC108935546	Reticulon-4 receptor-like. (481 aa)
	Z043_111050	Semaphorin-5B-like. (1089 aa)
	ulk1	Serine/threonine-protein kinase ULK1-like. (1030 aa)
	med23	Mediator of RNA polymerase II transcription subunit 23-like. (1451 aa)
	LOC108927316	Nuclear receptor subfamily 1 group D member 2-like. (584 aa)
	dnajb11	DnaJsubfamily B member 11-like. (450 aa)
	Z043_112734	Semaphorin-3E-like; Belongs to the semaphorin family. (749 aa)
	SEMA4D	Uncharacterized protein; Belongs to the semaphorin family. (901 aa)
	pcm1	Pericentriolar material 1 protein-like. (1962 aa)
	sema6a	Sema domain-containing protein; Belongs to the semaphorin family. (1004 aa)
	ID1	DNA-binding protein inhibitor ID-1-like. (134 aa)
	sema4b	Sema domain-containing protein; Belongs to the semaphorin family. (847 aa)
	RUFY3-2	RUN domain-containing protein. (575 aa)
	LOC108925664	Interferon-related developmental regulator 2-like. (462 aa)
	LOC108925639	Semaphorin-3G-like; Belongs to the semaphorin family. (785 aa)
	sema3b	Semaphorin-3B-like; Belongs to the semaphorin family. (799 aa)
	sema4c	Semaphorin-4C-like; Belongs to the semaphorin family. (852 aa)
	rtn4r	Reticulon-4 receptor-like. (481 aa)
	LOC108929719	Receptor protein-tyrosine kinase. (260 aa)
	LOC108918212	Nuclear receptor subfamily 1 group D member 1-like. (575 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2-like. (1644 aa)
	RUFY3	Protein RUFY3-like. (631 aa)
	LOC108919883	Transmembrane protein 98-like. (226 aa)
	Z043_118472	Homeobox protein Nkx-6-like. (310 aa)
	Z043_103397	Semaphorin-6D-like; Belongs to the semaphorin family. (1085 aa)
	LOC108935561	Uncharacterized protein. (1080 aa)
	LOC108941863	Sema domain-containing protein; Belongs to the semaphorin family. (627 aa)
	ENSSFOP00015018548	Si:ch211-129c21.1. (748 aa)
	LOC108941869	Semaphorin-4A-like. (759 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
	cdk5	Protein kinase domain-containing protein. (292 aa)
	LOC108942467	Sema domain-containing protein; Belongs to the semaphorin family. (841 aa)
	f2	Uncharacterized protein; Belongs to the peptidase S1 family. (622 aa)
	Z043_103463	Sema domain-containing protein; Belongs to the semaphorin family. (641 aa)
	LOC108931305	Semaphorin-3D-like; Belongs to the semaphorin family. (772 aa)
	Z043_116894	Disco-interacting protein 2C-like. (1629 aa)
	NEUROG1	Neurogenin-1-like. (174 aa)
	LOC108936519	Semaphorin-3A-like; Belongs to the semaphorin family. (777 aa)
	Z043_118184	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
	sirt2	Sirtuin 2 (Silent mating type information regulation 2) 2-like. (385 aa)
	LOC108931577	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	nkx6-2	Homeobox protein Nkx-6.2. (281 aa)
	rnf10	RING finger protein 10-like. (777 aa)
	spart	Spartin-like. (583 aa)
	nr1d1	NR1D1 protein-like. (622 aa)
	LOC108936434	DNA-binding protein inhibitor ID-1-like. (145 aa)
	DIP2B	Disco-interacting protein 2B-A-like. (1569 aa)
	Dynlt1	Dynein light chain Tctex-type 1. (148 aa)
	LOC108921721	Semaphorin-6B-like; Belongs to the semaphorin family. (857 aa)
	Z043_112106	Uncharacterized protein. (1332 aa)
	LOC108925526	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
	sema4g	Semaphorin-4G-like; Belongs to the semaphorin family. (951 aa)
	LOC108928369	Semaphorin-5B-like. (1127 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	LOC108926074	Protein kinase domain-containing protein. (622 aa)
	Z043_101951	Semaphorin-5A-like. (1094 aa)
	Z043_101981	Disco-interacting protein 2 B-like. (1591 aa)
	LOC108930147	Ig-like domain-containing protein. (659 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	sema3d	Semaphorin-3D. (797 aa)
	Kifap3	Kinesin-associated protein 3-like. (784 aa)
	notch1	Neurogenic locus notch protein-like. (2530 aa)
	LOC108921462	Tyrosine-protein kinase RYK-like. (645 aa)
	Z043_117814	Dynein light chain Tctex-type 1-like. (121 aa)
	Z043_111990	Retinoblastoma-associated protein-like. (877 aa)
	KIFAP3	Uncharacterized protein. (791 aa)
	LOC108941958	MIT domain-containing protein. (616 aa)
	Nfatc4	Nuclear factor of activated T-cells, cytoplasmic 4. (656 aa)
	Sorl1	Uncharacterized protein. (2205 aa)
	LOC108927313	FERM domain-containing protein. (614 aa)
	Nf1	Ras-GAP domain-containing protein. (2790 aa)
	LOC108921669	Sema domain-containing protein. (775 aa)

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIP2B	med23	ENSSFOP00015005756	ENSSFOP00015040695	Disco-interacting protein 2B-A-like.	Mediator of RNA polymerase II transcription subunit 23-like.	0.719
ENSSFOP00015058220	cdk5	ENSSFOP00015058220	ENSSFOP00015014299	Semaphorin-6B-like.	Protein kinase domain-containing protein.	0.476
LOC108921276	LOC108927313	ENSSFOP00015046003	ENSSFOP00015063364	Merlin-like.	FERM domain-containing protein.	0.901
LOC108921276	Nf1	ENSSFOP00015046003	ENSSFOP00015062168	Merlin-like.	Ras-GAP domain-containing protein.	0.518
LOC108921462	LOC108925526	ENSSFOP00015066509	ENSSFOP00015075438	Tyrosine-protein kinase RYK-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601
LOC108921462	LOC108926074	ENSSFOP00015066509	ENSSFOP00015071627	Tyrosine-protein kinase RYK-like.	Protein kinase domain-containing protein.	0.900
LOC108921462	LOC108931577	ENSSFOP00015066509	ENSSFOP00015010415	Tyrosine-protein kinase RYK-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.597
LOC108921462	WNT7A	ENSSFOP00015066509	ENSSFOP00015068935	Tyrosine-protein kinase RYK-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601
LOC108921462	Z043_118184	ENSSFOP00015066509	ENSSFOP00015000626	Tyrosine-protein kinase RYK-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.706
LOC108921462	wnt3a	ENSSFOP00015066509	ENSSFOP00015014818	Tyrosine-protein kinase RYK-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.706
LOC108921462	wnt7b	ENSSFOP00015066509	ENSSFOP00015072107	Tyrosine-protein kinase RYK-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.597
LOC108921721	cdk5	ENSSFOP00015076132	ENSSFOP00015014299	Semaphorin-6B-like; Belongs to the semaphorin family.	Protein kinase domain-containing protein.	0.476
LOC108925526	LOC108921462	ENSSFOP00015075438	ENSSFOP00015066509	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Tyrosine-protein kinase RYK-like.	0.601
LOC108925526	LOC108926074	ENSSFOP00015075438	ENSSFOP00015071627	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein kinase domain-containing protein.	0.601
LOC108925526	Z043_118184	ENSSFOP00015075438	ENSSFOP00015000626	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.423
LOC108925526	wnt3a	ENSSFOP00015075438	ENSSFOP00015014818	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.423
LOC108926074	LOC108921462	ENSSFOP00015071627	ENSSFOP00015066509	Protein kinase domain-containing protein.	Tyrosine-protein kinase RYK-like.	0.900
LOC108926074	LOC108925526	ENSSFOP00015071627	ENSSFOP00015075438	Protein kinase domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601
LOC108926074	LOC108931577	ENSSFOP00015071627	ENSSFOP00015010415	Protein kinase domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.597
LOC108926074	WNT7A	ENSSFOP00015071627	ENSSFOP00015068935	Protein kinase domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601