(14 nodes) Positive regulation of SMAD protein signal transduction network (Scleropages formosus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	SMAD4	Mothers against decapentaplegic homolog. (551 aa)
	LOC108920640	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1118 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1075 aa)
	LOC108932103	Bone morphogenetic protein 2-like. (428 aa)
	LOC108942527	Mothers against decapentaplegic homolog. (559 aa)
	LOC108941913	Mothers against decapentaplegic homolog 4-like. (564 aa)
	RBPMS	RNA-binding protein with multiple splicing-like. (194 aa)
	DAB2	DAB adaptor protein 2. (553 aa)
	LOC108924734	TGF beta-1-like. (382 aa)
	LOC108938584	Disabled2-like. (732 aa)
	LOC108933453	TGF-beta1B-like. (383 aa)
	BMP4	Bone morphogenetic protein 4-like. (399 aa)
	LOC108938820	RNA-binding protein with multiple splicing-like. (189 aa)
	LOC108924036	Bone morphogenetic protein 4-like. (402 aa)

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	LOC108920640	ENSSFOP00015016043	ENSSFOP00015028246	Bone morphogenetic protein 4-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.970
BMP4	LOC108924036	ENSSFOP00015016043	ENSSFOP00015005728	Bone morphogenetic protein 4-like.	Bone morphogenetic protein 4-like.	0.901
BMP4	LOC108941913	ENSSFOP00015016043	ENSSFOP00015064750	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4-like.	0.656
BMP4	LOC108942527	ENSSFOP00015016043	ENSSFOP00015047412	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog.	0.656
BMP4	SMAD4	ENSSFOP00015016043	ENSSFOP00015015148	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog.	0.709
BMP4	bmpr2	ENSSFOP00015016043	ENSSFOP00015038606	Bone morphogenetic protein 4-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.970
LOC108920640	BMP4	ENSSFOP00015028246	ENSSFOP00015016043	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4-like.	0.970
LOC108920640	LOC108924036	ENSSFOP00015028246	ENSSFOP00015005728	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4-like.	0.970
LOC108920640	LOC108924734	ENSSFOP00015028246	ENSSFOP00015049261	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF beta-1-like.	0.432
LOC108920640	LOC108932103	ENSSFOP00015028246	ENSSFOP00015043032	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2-like.	0.970
LOC108920640	LOC108933453	ENSSFOP00015028246	ENSSFOP00015023510	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF-beta1B-like.	0.432
LOC108920640	LOC108941913	ENSSFOP00015028246	ENSSFOP00015064750	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog 4-like.	0.688
LOC108920640	LOC108942527	ENSSFOP00015028246	ENSSFOP00015047412	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.688
LOC108920640	SMAD4	ENSSFOP00015028246	ENSSFOP00015015148	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.688
LOC108920640	bmpr2	ENSSFOP00015028246	ENSSFOP00015038606	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
LOC108924036	BMP4	ENSSFOP00015005728	ENSSFOP00015016043	Bone morphogenetic protein 4-like.	Bone morphogenetic protein 4-like.	0.901
LOC108924036	LOC108920640	ENSSFOP00015005728	ENSSFOP00015028246	Bone morphogenetic protein 4-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.970
LOC108924036	LOC108941913	ENSSFOP00015005728	ENSSFOP00015064750	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4-like.	0.656
LOC108924036	LOC108942527	ENSSFOP00015005728	ENSSFOP00015047412	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog.	0.656
LOC108924036	SMAD4	ENSSFOP00015005728	ENSSFOP00015015148	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog.	0.709