(32 nodes) Stem cell proliferation network (Scleropages formosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	xrcc5	Ku domain-containing protein. (746 aa)
	ythdf2	YTH domain-containing family protein 2-like. (613 aa)
	Z043_122107	Breast cancer type 2 susceptibility protein-like. (2902 aa)
	rnf43	Uncharacterized protein. (791 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	mecom	MDS1 and EVI1 complex locus protein EVI1-like. (1187 aa)
	SFRP2	Secreted frizzled-related protein 2-like. (293 aa)
	LOC108932817	Homeobox protein HMX2-like. (276 aa)
	ism1	AMOP domain-containing protein. (450 aa)
	Z043_123374	PNT domain-containing protein. (409 aa)
	lig4	DNA ligase. (909 aa)
	LOC108933453	TGF-beta1B-like. (383 aa)
	LOC108924426	Secreted frizzled-related protein 2-like. (302 aa)
	arih2	RBR-type E3 ubiquitin transferase. (508 aa)
	znrf3	E3 ubiquitin-protein ligase ZNRF3-like. (869 aa)
	LOC108930616	N6-adenosine-methyltransferase subunit-like; Belongs to the MT-A70-like family. (591 aa)
	LOC108930616-2	N6-adenosine-methyltransferase subunit METTL3. (591 aa)
	LOC108924734	TGF beta-1-like. (382 aa)
	LOC108932225	Secreted frizzled-related protein 2-like. (308 aa)
	SCRG1	Scrapie-responsive protein 1 isoform X2. (163 aa)
	KDF1	Uncharacterized protein. (373 aa)
	LOC108923654	Uncharacterized protein. (379 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
	Nf1	Ras-GAP domain-containing protein. (2790 aa)
	cep120	Centrosomal protein of 120 kDa-like. (987 aa)
	ETV6	LOW QUALITY PROTEIN: transcription factor ETV6-like. (427 aa)
	cdkn2c	Cyclin-dependent kinase 4 inhibitor C-like. (166 aa)
	TRIM71	E3 ubiquitin-protein ligase TRIM71-like. (826 aa)
	bysl	Bystin-like. (441 aa)
	ENSSFOP00015077961	annotation not available (283 aa)
	ercc2	TFIIH basal transcription factor complex helicase XPD subunit-like. (760 aa)
	Z043_102159	E3 ubiquitin-protein ligase TRIM71-like. (813 aa)

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSFOP00015077961	ythdf2	ENSSFOP00015077961	ENSSFOP00015002297	annotation not available	YTH domain-containing family protein 2-like.	0.492
LOC108924734	LOC108933453	ENSSFOP00015049261	ENSSFOP00015023510	TGF beta-1-like.	TGF-beta1B-like.	0.901
LOC108924734	fgf2	ENSSFOP00015049261	ENSSFOP00015003594	TGF beta-1-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.451
LOC108924734	fgf4	ENSSFOP00015049261	ENSSFOP00015056738	TGF beta-1-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.403
LOC108930616	ythdf2	ENSSFOP00015034865	ENSSFOP00015002297	N6-adenosine-methyltransferase subunit-like; Belongs to the MT-A70-like family.	YTH domain-containing family protein 2-like.	0.461
LOC108930616-2	ythdf2	ENSSFOP00015034877	ENSSFOP00015002297	N6-adenosine-methyltransferase subunit METTL3.	YTH domain-containing family protein 2-like.	0.461
LOC108933453	LOC108924734	ENSSFOP00015023510	ENSSFOP00015049261	TGF-beta1B-like.	TGF beta-1-like.	0.901
LOC108933453	fgf2	ENSSFOP00015023510	ENSSFOP00015003594	TGF-beta1B-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.451
LOC108933453	fgf4	ENSSFOP00015023510	ENSSFOP00015056738	TGF-beta1B-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.403
Nf1	Z043_122107	ENSSFOP00015062168	ENSSFOP00015002218	Ras-GAP domain-containing protein.	Breast cancer type 2 susceptibility protein-like.	0.577
Z043_122107	Nf1	ENSSFOP00015002218	ENSSFOP00015062168	Breast cancer type 2 susceptibility protein-like.	Ras-GAP domain-containing protein.	0.577
Z043_122107	ercc2	ENSSFOP00015002218	ENSSFOP00015009696	Breast cancer type 2 susceptibility protein-like.	TFIIH basal transcription factor complex helicase XPD subunit-like.	0.678
Z043_122107	lig4	ENSSFOP00015002218	ENSSFOP00015019949	Breast cancer type 2 susceptibility protein-like.	DNA ligase.	0.673
Z043_122107	xrcc5	ENSSFOP00015002218	ENSSFOP00015048073	Breast cancer type 2 susceptibility protein-like.	Ku domain-containing protein.	0.574
ercc2	Z043_122107	ENSSFOP00015009696	ENSSFOP00015002218	TFIIH basal transcription factor complex helicase XPD subunit-like.	Breast cancer type 2 susceptibility protein-like.	0.678
ercc2	lig4	ENSSFOP00015009696	ENSSFOP00015019949	TFIIH basal transcription factor complex helicase XPD subunit-like.	DNA ligase.	0.652
ercc2	xrcc5	ENSSFOP00015009696	ENSSFOP00015048073	TFIIH basal transcription factor complex helicase XPD subunit-like.	Ku domain-containing protein.	0.574
fgf2	LOC108924734	ENSSFOP00015003594	ENSSFOP00015049261	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	TGF beta-1-like.	0.451
fgf2	LOC108933453	ENSSFOP00015003594	ENSSFOP00015023510	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	TGF-beta1B-like.	0.451
fgf2	fgf4	ENSSFOP00015003594	ENSSFOP00015056738	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.501