(34 nodes) Frizzled cysteine-rich domain superfamily network (Scleropages formosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108925702	Carboxypeptidase Z-like. (671 aa)
	ror1	Uncharacterized protein. (951 aa)
	Frzb	Secreted frizzled-related protein 3-like. (287 aa)
	Fzd10	Frizzled-10-like; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	FZD9	Frizzled-9-like; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
	Z043_111370	Secreted frizzled-related protein 5-like. (280 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (707 aa)
	Z043_117251	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (599 aa)
	FZD7	Frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
	mfrp	Membrane frizzled-related protein-like. (585 aa)
	FZD1	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa)
	SFRP2	Secreted frizzled-related protein 2-like. (293 aa)
	SFRP1	FZ domain-containing protein. (309 aa)
	LOC108924426	Secreted frizzled-related protein 2-like. (302 aa)
	LOC108922583	FZ domain-containing protein. (301 aa)
	SFRP4	Secreted frizzled-related protein 4-like. (302 aa)
	LOC108942624	Secreted frizzled-related protein 5-like. (309 aa)
	fzd4	Frizzled-4-like; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	CPZ	Carboxypeptidase Z-like. (670 aa)
	Z043_121820	Frizzled7a-like; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
	Z043_106673	Uncharacterized protein. (272 aa)
	LOC108923450	Frizzled-3-like; Belongs to the G-protein coupled receptor Fz/Smo family. (694 aa)
	sfrp5	Secreted frizzled-related protein 5-like. (323 aa)
	Fzd2	Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (539 aa)
	fzd5	Frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
	ror2	Tyrosine-protein kinase transmembrane receptor ROR2-like. (947 aa)
	LOC108932225	Secreted frizzled-related protein 2-like. (308 aa)
	smo	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (816 aa)
	FZD3	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family. (671 aa)
	Z043_125644	Frizzled-9-like; Belongs to the G-protein coupled receptor Fz/Smo family. (602 aa)
	Z043_109768	Tyrosine-protein kinase transmembrane receptor ROR1-like. (892 aa)
	corin	Atrial natriuretic peptide-converting enzyme-like. (1099 aa)
	MUSK	Muscle, skeletal receptor tyrosine protein kinase-like. (944 aa)
	LOC108933855	Pituitary tumor-transforming protein-interacting protein 1-like. (321 aa)

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FZD1	LOC108922583	ENSSFOP00015013418	ENSSFOP00015024001	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	FZ domain-containing protein.	0.682
FZD1	LOC108924426	ENSSFOP00015013418	ENSSFOP00015023795	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.684
FZD1	LOC108932225	ENSSFOP00015013418	ENSSFOP00015050950	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.684
FZD1	LOC108942624	ENSSFOP00015013418	ENSSFOP00015025090	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5-like.	0.682
FZD1	SFRP1	ENSSFOP00015013418	ENSSFOP00015020501	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	FZ domain-containing protein.	0.682
FZD1	SFRP2	ENSSFOP00015013418	ENSSFOP00015013523	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.683
FZD1	Z043_109768	ENSSFOP00015013418	ENSSFOP00015068038	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Tyrosine-protein kinase transmembrane receptor ROR1-like.	0.799
FZD1	fzd4	ENSSFOP00015013418	ENSSFOP00015025899	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-4-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.440
FZD1	ror1	ENSSFOP00015013418	ENSSFOP00015001655	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.799
FZD1	ror2	ENSSFOP00015013418	ENSSFOP00015039127	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Tyrosine-protein kinase transmembrane receptor ROR2-like.	0.799
FZD1	sfrp5	ENSSFOP00015013418	ENSSFOP00015033380	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5-like.	0.682
FZD3	FZD9	ENSSFOP00015062810	ENSSFOP00015007325	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-9-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.410
FZD3	Fzd10	ENSSFOP00015062810	ENSSFOP00015004727	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-10-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.410
FZD3	LOC108922583	ENSSFOP00015062810	ENSSFOP00015024001	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	FZ domain-containing protein.	0.736
FZD3	LOC108924426	ENSSFOP00015062810	ENSSFOP00015023795	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.716
FZD3	LOC108932225	ENSSFOP00015062810	ENSSFOP00015050950	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.716
FZD3	LOC108942624	ENSSFOP00015062810	ENSSFOP00015025090	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5-like.	0.736
FZD3	SFRP1	ENSSFOP00015062810	ENSSFOP00015020501	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	FZ domain-containing protein.	0.736
FZD3	SFRP2	ENSSFOP00015062810	ENSSFOP00015013523	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.716
FZD3	Z043_109768	ENSSFOP00015062810	ENSSFOP00015068038	Fzd3 protein-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Tyrosine-protein kinase transmembrane receptor ROR1-like.	0.770