STRINGSTRING
FRS2 FRS2 LOC108918505 LOC108918505 MKNK2 MKNK2 gab1 gab1 Z043_111414 Z043_111414 LOC108942017 LOC108942017 Rps27a Rps27a Z043_119420 Z043_119420 fgf1 fgf1 LOC108940343 LOC108940343 uba52 uba52 cblc cblc plcg1 plcg1 LOC108938118 LOC108938118 LOC108923074 LOC108923074 polr2i polr2i GALNT3 GALNT3 polr2a polr2a Z043_124132 Z043_124132 KRAS KRAS Klb Klb polr2d polr2d Polr2b Polr2b Z043_121486 Z043_121486 MAPK3 MAPK3 ANOS1 ANOS1 SPRED2 SPRED2 tial1 tial1 polr2f polr2f LOC108931121 LOC108931121 NCBP1 NCBP1 Fgfr2 Fgfr2 SRC SRC Z043_110967 Z043_110967 Mapk1 Mapk1 fgf10 fgf10 Z043_123645 Z043_123645 Z043_108299 Z043_108299 LOC108926447 LOC108926447 LOC108929745 LOC108929745 Z043_119744 Z043_119744 ANOS1-2 ANOS1-2 LOC108931493 LOC108931493 fgf17 fgf17 Z043_124551 Z043_124551 Csde1 Csde1 LOC114910717 LOC114910717 LOC108925344 LOC108925344 kl kl LOC108924027 LOC108924027 Shc1 Shc1 ptbp2 ptbp2 LOC108933921 LOC108933921 LOC108929959 LOC108929959 polr2c polr2c fgf4 fgf4 fgf20 fgf20 fgfr3 fgfr3 LOC108928737 LOC108928737 polr2j polr2j LOC108939332 LOC108939332 Z043_121655 Z043_121655 LOC108935247 LOC108935247 polr2l polr2l LOC108936239 LOC108936239 LOC108939904 LOC108939904 Z043_108300 Z043_108300 Z043_125466 Z043_125466 GRB2 GRB2 ppp2cb ppp2cb LOC108939128 LOC108939128 FGF7 FGF7 fndc3a fndc3a LOC108933921-2 LOC108933921-2 fgf8 fgf8 Z043_122986 Z043_122986 ptbp1 ptbp1 LOC108939428 LOC108939428 nras nras LOC108933025 LOC108933025 polr2e polr2e fgfrl1 fgfrl1 FLRT3 FLRT3 LOC108933757 LOC108933757 polr2g polr2g LOC108919895 LOC108919895 LOC108920920 LOC108920920 LOC108928618 LOC108928618 LOC108934452 LOC108934452 fgf2 fgf2 LOC108934097 LOC108934097 LOC108922913 LOC108922913 polr2k polr2k Hras Hras ENSSFOP00015004954 ENSSFOP00015004954 LOC108934179 LOC108934179 flrt2 flrt2 LOC108919805 LOC108919805 LOC108918664 LOC108918664 fgf23 fgf23 Z043_120772 Z043_120772 fgf3 fgf3 gtf2f2 gtf2f2 Fgf19 Fgf19 flrt1 flrt1 Z043_107977 Z043_107977 PIK3CA PIK3CA LOC108927766 LOC108927766 esrp1 esrp1 LOC108941738 LOC108941738 lctl lctl CBL CBL Hnrnpm Hnrnpm LOC108918868 LOC108918868 fndc3b fndc3b esrp2 esrp2 FGF22 FGF22 fgfr4 fgfr4 flrt3 flrt3 LOC108934636 LOC108934636 LOC108925438 LOC108925438 LOC108939257 LOC108939257 FGF3 FGF3 Fgfbp3 Fgfbp3 LOC108918221 LOC108918221 PIK3CA-2 PIK3CA-2 fgf5 fgf5 polr2h polr2h ENSSFOP00015023217 ENSSFOP00015023217 LOC108921603 LOC108921603
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FRS2Uncharacterized protein. (529 aa)
LOC108918505Uncharacterized protein. (340 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2-like. (478 aa)
gab1GRB2-associated-binding protein 1-like. (725 aa)
Z043_111414Anosmin-1-like. (630 aa)
LOC108942017Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
Rps27aUbiquitin and ribosomal protein S27a-like protein-like. (177 aa)
Z043_119420Uncharacterized protein. (1172 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (183 aa)
LOC108940343Nucleolysin TIA-1-like. (389 aa)
uba52Ubiquitin-large subunit ribosomal protein L40e. (128 aa)
cblcE3 ubiquitin-protein ligase CBL-C-like. (612 aa)
plcg1Phosphoinositide phospholipase C. (1320 aa)
LOC108938118Serine/threonine-protein phosphatase. (309 aa)
LOC108923074Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (625 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1968 aa)
Z043_124132Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (510 aa)
KRASGTPase KRas isoform X1. (189 aa)
KlbBeta-klotho-like. (1020 aa)
polr2dDNA-directed RNA polymerase II subunit RPB4-like. (144 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1182 aa)
Z043_121486Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ANOS1Anosmin-1-like. (670 aa)
SPRED2Sprouty-related, EVH1 domain-containing protein 2-like. (421 aa)
tial1Nucleolysin TIAR-like. (408 aa)
polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2-like. (127 aa)
LOC108931121Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
NCBP1Nuclear cap-binding protein subunit 1-like. (843 aa)
Fgfr2Fibroblast growth factor receptor 2-like. (827 aa)
SRCProto-oncogene tyrosine-protein kinase Src-like. (554 aa)
Z043_110967Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
Mapk1Mitogen-activated protein kinase 1-like. (404 aa)
fgf10Fibroblast growth factor 10-like. (264 aa)
Z043_123645Uncharacterized protein. (823 aa)
Z043_108299Fibroblast growth factor-binding protein 1-like. (351 aa)
LOC108926447Phosphoinositide phospholipase C. (1402 aa)
LOC108929745Serine/threonine-protein phosphatase. (309 aa)
Z043_119744Lactase-phlorizin hydrolase-like. (1912 aa)
ANOS1-2Anosmin-1-like. (674 aa)
LOC108931493Fibroblast growth factor 6-like. (206 aa)
fgf17Uncharacterized protein. (209 aa)
Z043_124551FGF8 protein-like; Belongs to the heparin-binding growth factors family. (210 aa)
Csde1Cold shock domain-containing protein E1-like. (882 aa)
LOC114910717Polyubiquitin-C. (381 aa)
LOC108925344Fibroblast growth factor 18-like; Belongs to the heparin-binding growth factors family. (208 aa)
klKlotho-like. (986 aa)
LOC108924027Sprouty-related, EVH1 domain-containing protein 1-like. (435 aa)
Shc1SHC-transforming protein 1-like. (561 aa)
ptbp2Polypyrimidine tract-binding protein 2-like. (522 aa)
LOC108933921GTPase KRas-like. (187 aa)
LOC108929959Nucleolysin TIA-1-like. (428 aa)
polr2cDNA-directed RNA polymerase II subunit RPB3-like. (275 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
fgfr3Protein kinase domain-containing protein. (846 aa)
LOC108928737Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta-like. (656 aa)
polr2jDNA-directed RNA polymerase II subunit RPB11-a. (130 aa)
LOC108939332Uncharacterized protein. (360 aa)
Z043_121655Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (829 aa)
LOC108935247Polypyrimidine tract-binding protein 2-like. (592 aa)
polr2lUncharacterized protein. (67 aa)
LOC108936239Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta-like. (636 aa)
LOC108939904Uncharacterized protein. (217 aa)
Z043_108300Fibroblast growth factor binding protein 2b-like. (238 aa)
Z043_125466IRS-type PTB domain-containing protein. (506 aa)
GRB2Uncharacterized protein. (217 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC108939128Tyrosine-protein kinase. (548 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fndc3aFibronectin type-III domain-containing protein 3A-like. (1217 aa)
LOC108933921-2GTPase KRas-like. (187 aa)
fgf8Fibroblast growth factor 8. (208 aa)
Z043_122986Fibroblast growth factor-binding protein 2-like. (223 aa)
ptbp1Polypyrimidine tract-binding protein 1-like. (578 aa)
LOC108939428Polypeptide N-acetylgalactosaminyltransferase. (621 aa)
nrasGTPase NRas-like. (188 aa)
LOC108933025Mitogen-activated protein kinase. (507 aa)
polr2eDNA-directed RNA polymerases i II and III subunit rpabc1-like. (233 aa)
fgfrl1Fibroblast growth factor receptor-like 1-like. (494 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3-like. (649 aa)
LOC108933757Sprouty-related, EVH1 domain-containing protein 2-like. (414 aa)
polr2gDNA-directed RNA polymerase II subunit RPB7-like. (180 aa)
LOC108919895MAP kinase-interacting serine/threonine-protein kinase 2-like; Belongs to the protein kinase superfamily. (493 aa)
LOC108920920Fibroblast growth factor receptor substrate 2-like. (513 aa)
LOC108928618E3 ubiquitin-protein ligase CBL-like. (892 aa)
LOC108934452Serine/threonine-protein phosphatase. (309 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC108934097Fibronectin type-III domain-containing protein. (692 aa)
LOC108922913Uncharacterized protein. (485 aa)
polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4-like. (58 aa)
HrasHa-ras Harvey sarcoma viral oncogeneb-like. (203 aa)
ENSSFOP00015004954Protein sprouty homolog 2-like. (292 aa)
LOC108934179Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
flrt2Leucine-rich repeat transmembrane protein FLRT2-like. (663 aa)
LOC108919805Uncharacterized protein. (222 aa)
LOC108918664Fibroblast growth factor 6-like. (206 aa)
fgf23Uncharacterized protein. (253 aa)
Z043_120772Protein sprouty2-like. (360 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (263 aa)
Fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
flrt1LRRCT domain-containing protein. (702 aa)
Z043_107977Fibroblast growth factor 18a-like; Belongs to the heparin-binding growth factors family. (202 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC108927766Fibronectin type III domain-containing protein 3B-like. (1185 aa)
esrp1Epithelial splicing regulatory protein 1-like. (721 aa)
LOC108941738Uncharacterized protein. (187 aa)
lctlLactase-like protein-like; Belongs to the glycosyl hydrolase 1 family. (588 aa)
CBLUncharacterized protein. (912 aa)
HnrnpmHeterogeneous nuclear ribonucleoprotein M-like. (649 aa)
LOC108918868Fibroblast growth factor 18-like; Belongs to the heparin-binding growth factors family. (210 aa)
fndc3bFibronectin type III domain-containing protein 3B-like. (1199 aa)
esrp2Epithelial splicing regulatory protein 2-like. (734 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
fgfr4Fibroblast growth factor receptor. (930 aa)
flrt3Leucine-rich repeat transmembrane protein FLRT3-like. (648 aa)
LOC108934636GTPase HRas. (290 aa)
LOC108925438Fibronectin type-III domain-containing protein 3A-like. (1197 aa)
LOC108939257Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
Fgfbp3Fibroblast growth factor-binding protein 3. (208 aa)
LOC108918221Polypeptide N-acetylgalactosaminyltransferase. (620 aa)
PIK3CA-2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha-like; Belongs to the PI3/PI4-kinase family. (1068 aa)
fgf5Uncharacterized protein; Belongs to the heparin-binding growth factors family. (230 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSSFOP00015023217annotation not available (672 aa)
LOC108921603Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
Your Current Organism:
Scleropages formosus
NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish
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