(33 nodes) Mixed, incl. Biosynthesis of siderophore group nonribosomal peptides, and AMP-binding enzyme network (Gordonia phthalatica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALG83378.1	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
	ALG83379.1	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1764 aa)
	ALG83568.1	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
	ALG83705.1	fatty-acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
	ALG83801.1	Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
	ALG86601.1	Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	ALG83964.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
	ALG83965.1	O-succinylbenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
	ALG86639.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
	ALG84179.1	Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family. (406 aa)
	ALG84180.1	Cholesterol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
	ALG84201.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
	ALG84387.1	3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3073 aa)
	ALG84764.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
	ALG84881.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1414 aa)
	ALG85318.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
	ALG85356.1	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
	ALG85665.1	Antibiotic synthesis protein MbtH; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
	ALG85666.1	Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2663 aa)
	ALG85780.1	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
	ALG85955.1	Steroid C27-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family. (423 aa)
	ALG86103.1	Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1494 aa)
	ALG86104.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1744 aa)
	ALG86106.1	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1015 aa)
	ALG86107.1	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (437 aa)
	ALG86108.1	Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
	ALG86109.1	N6-hydroxylysine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
	ALG87023.1	Lysine 6-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
	ALG87024.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (1159 aa)
	ALG86110.1	Salicylate synthase MbtI; Catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
	ALG86111.1	Triostin synthetase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
	ALG86119.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	ALG86342.1	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)

Your Current Organism:

Gordonia phthalatica

NCBI taxonomy Id: 1136941
Other names: CICC 24107, G. phthalatica, Gordonia phthalatica Jin et al. 2017, Gordonia sp. QH-11, KCTC 39933, strain QH-11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG83378.1	ALG83379.1	ACH46_01180	ACH46_01185	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
ALG83378.1	ALG83801.1	ACH46_01180	ACH46_03875	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
ALG83378.1	ALG83965.1	ACH46_01180	ACH46_04860	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	O-succinylbenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.690
ALG83378.1	ALG84179.1	ACH46_01180	ACH46_06240	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.	0.613
ALG83378.1	ALG84387.1	ACH46_01180	ACH46_07590	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436
ALG83378.1	ALG84881.1	ACH46_01180	ACH46_10690	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.839
ALG83378.1	ALG85318.1	ACH46_01180	ACH46_13585	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.488
ALG83378.1	ALG85665.1	ACH46_01180	ACH46_15755	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Antibiotic synthesis protein MbtH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.539
ALG83378.1	ALG85666.1	ACH46_01180	ACH46_15765	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
ALG83378.1	ALG85955.1	ACH46_01180	ACH46_17490	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Steroid C27-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.	0.563
ALG83378.1	ALG86103.1	ACH46_01180	ACH46_18390	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.961
ALG83378.1	ALG86104.1	ACH46_01180	ACH46_18395	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
ALG83378.1	ALG86106.1	ACH46_01180	ACH46_18405	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
ALG83378.1	ALG86107.1	ACH46_01180	ACH46_18410	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.980
ALG83378.1	ALG86108.1	ACH46_01180	ACH46_18415	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.588
ALG83378.1	ALG86111.1	ACH46_01180	ACH46_18440	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Triostin synthetase I; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.511
ALG83378.1	ALG86119.1	ACH46_01180	ACH46_18485	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.590
ALG83378.1	ALG87024.1	ACH46_01180	ACH46_18430	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.947
ALG83379.1	ALG83378.1	ACH46_01185	ACH46_01180	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
ALG83379.1	ALG83568.1	ACH46_01185	ACH46_02395	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.767