node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFE07758.1 | metH | COCOR_07811 | COCOR_01995 | B12-binding domain-containing protein. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.475 |
carH | metH | COCOR_00789 | COCOR_01995 | Transcriptional regulator CarH. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.640 |
carH | sbm | COCOR_00789 | COCOR_06686 | Transcriptional regulator CarH. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.448 |
carH | yehV | COCOR_00789 | COCOR_00788 | Transcriptional regulator CarH. | Transcriptional repressor CarA. | 0.798 |
kamE | metH | COCOR_03527 | COCOR_01995 | D-lysine 5,6-aminomutase subunit beta. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.444 |
metH | AFE07758.1 | COCOR_01995 | COCOR_07811 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | B12-binding domain-containing protein. | 0.475 |
metH | carH | COCOR_01995 | COCOR_00789 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transcriptional regulator CarH. | 0.640 |
metH | kamE | COCOR_01995 | COCOR_03527 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | D-lysine 5,6-aminomutase subunit beta. | 0.444 |
metH | mutA | COCOR_01995 | COCOR_06683 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA mutase subunit beta. | 0.576 |
metH | mutB | COCOR_01995 | COCOR_06684 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA mutase. | 0.591 |
metH | sbm | COCOR_01995 | COCOR_06686 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.487 |
metH | yehV | COCOR_01995 | COCOR_00788 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transcriptional repressor CarA. | 0.625 |
mutA | metH | COCOR_06683 | COCOR_01995 | methylmalonyl-CoA mutase subunit beta. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.576 |
mutA | mutB | COCOR_06683 | COCOR_06684 | methylmalonyl-CoA mutase subunit beta. | methylmalonyl-CoA mutase. | 0.999 |
mutA | sbm | COCOR_06683 | COCOR_06686 | methylmalonyl-CoA mutase subunit beta. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.999 |
mutB | metH | COCOR_06684 | COCOR_01995 | methylmalonyl-CoA mutase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.591 |
mutB | mutA | COCOR_06684 | COCOR_06683 | methylmalonyl-CoA mutase. | methylmalonyl-CoA mutase subunit beta. | 0.999 |
mutB | sbm | COCOR_06684 | COCOR_06686 | methylmalonyl-CoA mutase. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.999 |
sbm | carH | COCOR_06686 | COCOR_00789 | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | Transcriptional regulator CarH. | 0.448 |
sbm | metH | COCOR_06686 | COCOR_01995 | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.487 |