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BRADO3367 BRADO3367 BRADO6960 BRADO6960 putA putA lysA lysA BRADO6462 BRADO6462 BRADO6431 BRADO6431 gltD gltD gltB gltB aroE-2 aroE-2 BRADO5884 BRADO5884 BRADO5883 BRADO5883 aroE-3 aroE-3 fumC fumC BRADO5508 BRADO5508 BRADO5322 BRADO5322 BRADO5313 BRADO5313 BRADO5270 BRADO5270 frc frc BRADO4810 BRADO4810 BRADO4760 BRADO4760 acpXL acpXL BRADO4598 BRADO4598 nadA nadA dapA dapA BRADO4310 BRADO4310 asd-2 asd-2 BRADO3770 BRADO3770 aroG aroG BRADO3483 BRADO3483 BRADO3421 BRADO3421 BRADO3383 BRADO3383 BRADO3250 BRADO3250 glsA glsA BRADO3125 BRADO3125 BRADO3032 BRADO3032 BRADO2922 BRADO2922 folP folP folB folB folK folK ppc ppc aroE aroE aroC aroC BRADO2030 BRADO2030 BRADO1813 BRADO1813 hutU hutU hutH hutH hutI hutI kdgD kdgD BRADO1544 BRADO1544 kynU kynU BRADO1514 BRADO1514 BRADO1441 BRADO1441 BRADO1428 BRADO1428 aroQ2 aroQ2 dapA-2 dapA-2 BRADO0968 BRADO0968 dapD dapD dapE dapE BRADO0693 BRADO0693 aroK-2 aroK-2 lysC lysC dapF dapF asd asd BRADO0276 BRADO0276 dapB dapB BRADO0103 BRADO0103 aroA aroA BRADO0088 BRADO0088 BRADO0047 BRADO0047
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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BRADO3367Putative bifunctional enzyme: malic oxidoreductase (N-terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (770 aa)
BRADO6960Putative Alpha-methylacyl-CoA racemase (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (370 aa)
putABifunctional putA protein: proline dehydrogenase (N-terminal); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1031 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (446 aa)
BRADO6462Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (277 aa)
BRADO6431Putative Peptidase family M20/M25/M40; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (418 aa)
gltDGlutamate synthase [NADPH] small chain, (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (482 aa)
gltBGlutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1578 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
BRADO5884Putative C-terminal domain of alpha subunit of Glutamate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (227 aa)
BRADO5883Putative large subunit of glutamate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutamate synthase family. (441 aa)
aroE-3Putative Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (293 aa)
fumCFumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (474 aa)
BRADO5508Putative isocitrate lyase-family protein, Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (292 aa)
BRADO5322Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Function of strongly homologous gene; enzyme. (543 aa)
BRADO5313Putative Formyl-coenzyme A transferase (Formyl-CoA transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (427 aa)
BRADO5270Putative Formyl-CoA transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (396 aa)
frcPutative formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate (By similarity); Belongs to the CoA-transferase III family. Frc subfamily. (425 aa)
BRADO4810Putative carnitine dehydratase/acyl-CoA transferases-related (COG1804); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (384 aa)
BRADO4760Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (415 aa)
acpXLAcyl carrier protein; Function of homologous gene experimentally demonstrated in an other organism; carrier. (93 aa)
BRADO4598Acetylornithine deacetylase(fragment); Gene remnant. (56 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
BRADO4310Putative dihydrodipicolinate synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapA family. (317 aa)
asd-2Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
BRADO3770Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (77 aa)
aroGPhospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (361 aa)
BRADO3483Hypothetical protein; No homology to any previously reported sequences. (358 aa)
BRADO3421Putative peptidase M20 family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (432 aa)
BRADO3383Putative peptidase M20 family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (426 aa)
BRADO3250Putative Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (288 aa)
glsAPutative glutaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutaminase family. (620 aa)
BRADO3125Putative Formyl-CoA transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (401 aa)
BRADO3032Putative L-carnitine dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (408 aa)
BRADO2922Putative carboxypeptidase G2 (Folate hydrolase G2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (376 aa)
folPDihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa)
folBDihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa)
folK2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Function of strongly homologous gene; enzyme. (163 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (933 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa)
aroCChorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa)
BRADO2030Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (81 aa)
BRADO1813Dihydrodipicolinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DapA family. (311 aa)
hutUUrocanate hydratase (Urocanase) (Imidazolonepropionate hydrolase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)
hutHHistidine ammonia-lyase (Histidase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PAL/histidase family. (515 aa)
hutIImidazolonepropionase (Imidazolone-5-propionate hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (404 aa)
kdgD5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy-glucarate dehydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DapA family. (314 aa)
BRADO1544Amidohydrolase family enzyme, putative Imidazolonepropionase; Function of strongly homologous gene; enzyme. (535 aa)
kynUPutative Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (397 aa)
BRADO1514Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (196 aa)
BRADO1441Formyl-coenzyme A transferase NAD(P)-binding; Function of strongly homologous gene; enzyme; Belongs to the CoA-transferase III family. (370 aa)
BRADO1428Acyl-coenzyme A transferase; Function of strongly homologous gene; enzyme; Belongs to the CoA-transferase III family. (424 aa)
aroQ23-dehydroquinate dehydratase type 2; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (161 aa)
dapA-2Putative dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (306 aa)
BRADO0968Putative Shikimate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (268 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. (281 aa)
dapESuccinyl-diaminopimelate desuccinylase (SDAP); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (384 aa)
BRADO0693Putative glutamate synthase domain 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutamate synthase family. (561 aa)
aroK-2Bifunctional: shikimate kinase (N-terminal); Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (600 aa)
lysCAspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (418 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (289 aa)
asdAspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
BRADO0276Putative Gly-X carboxypeptidase (CPS1); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (470 aa)
dapBDihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (272 aa)
BRADO0103Putative caiB/baiF CoA-transferase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CoA-transferase III family. (400 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (445 aa)
BRADO0088Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. (447 aa)
BRADO0047Putative peptidase M20 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (376 aa)
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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