(5 nodes) One-carbon metabolic process network (Blastococcus saxobsidens)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	BLASA_2587	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (198 aa)
	BLASA_2590	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (213 aa)
	folD	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
	purU	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa)
	folD2	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa)

Your Current Organism:

Blastococcus saxobsidens

NCBI taxonomy Id: 1146883
Other names: B. saxobsidens DD2, Blastococcus saxobsidens DD2, Blastococcus saxobsidens str. DD2, Blastococcus saxobsidens strain DD2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLASA_2587	BLASA_2590	BLASA_2587	BLASA_2590	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.922
BLASA_2587	folD	BLASA_2587	BLASA_2591	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.920
BLASA_2587	folD2	BLASA_2587	BLASA_4211	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.920
BLASA_2590	BLASA_2587	BLASA_2590	BLASA_2587	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.922
BLASA_2590	folD	BLASA_2590	BLASA_2591	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.962
BLASA_2590	folD2	BLASA_2590	BLASA_4211	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.927
BLASA_2590	purU	BLASA_2590	BLASA_2611	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	0.903
folD	BLASA_2587	BLASA_2591	BLASA_2587	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.920
folD	BLASA_2590	BLASA_2591	BLASA_2590	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.962
folD	folD2	BLASA_2591	BLASA_4211	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.908
folD	purU	BLASA_2591	BLASA_2611	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	0.962
folD2	BLASA_2587	BLASA_4211	BLASA_2587	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.920
folD2	BLASA_2590	BLASA_4211	BLASA_2590	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.927
folD2	folD	BLASA_4211	BLASA_2591	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.908
folD2	purU	BLASA_4211	BLASA_2611	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	0.960
purU	BLASA_2590	BLASA_2611	BLASA_2590	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	Putative methenyltetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.903
purU	folD	BLASA_2611	BLASA_2591	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.962
purU	folD2	BLASA_2611	BLASA_4211	Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.960