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thiE thiE thiG thiG thiS thiS thiO thiO thiE2 thiE2 BLASA_0102 BLASA_0102 BLASA_0103 BLASA_0103 tenA tenA thiD thiD BLASA_4996 BLASA_4996
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thiEThiamine monophosphate synthase; Function of strongly homologous gene; enzyme. (200 aa)
thiGThiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (277 aa)
thiSThiamine biosynthesis protein ThiS; Function of strongly homologous gene; factor. (66 aa)
thiOGlycine oxidase; Function of strongly homologous gene; enzyme. (370 aa)
thiE2Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (208 aa)
BLASA_0102Permease for cytosine/purines uracil thiamine allantoin; Function of strongly homologous gene; transporter. (445 aa)
BLASA_0103Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (198 aa)
tenAThiaminase-2; Function of strongly homologous gene; enzyme. (211 aa)
thiDBifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (284 aa)
BLASA_4996Conserved protein of unknown function, putative transcription activator domain; Homologs of previously reported genes of unknown function. (219 aa)
Your Current Organism:
Blastococcus saxobsidens
NCBI taxonomy Id: 1146883
Other names: B. saxobsidens DD2, Blastococcus saxobsidens DD2, Blastococcus saxobsidens str. DD2, Blastococcus saxobsidens strain DD2
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