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BLASA_0103 BLASA_0103 tenA tenA bar bar arcA arcA BLASA_0397 BLASA_0397 tadA tadA def-2 def-2 folE folE BLASA_0598 BLASA_0598 BLASA_0632 BLASA_0632 mshB mshB dapE dapE pxpA pxpA FCA1 FCA1 BLASA_1131 BLASA_1131 pncA pncA amiB amiB ribBA ribBA BLASA_1433 BLASA_1433 ribBA2 ribBA2 nylA nylA def def argE argE fmdA fmdA nadE nadE BLASA_1997 BLASA_1997 nadE2 nadE2 BLASA_2226 BLASA_2226 hisH hisH hisI hisI pdxT pdxT pyrC pyrC def2 def2 ribD ribD ribBA3 ribBA3 BLASA_2428 BLASA_2428 pyrG pyrG BLASA_2526 BLASA_2526 BLASA_2541 BLASA_2541 BLASA_2542 BLASA_2542 folD folD purU purU BLASA_2628 BLASA_2628 BLASA_2653 BLASA_2653 dop dop BLASA_2775 BLASA_2775 ribBA4 ribBA4 BLASA_2930 BLASA_2930 BLASA_2972 BLASA_2972 BLASA_2986 BLASA_2986 ansA ansA BLASA_3117 BLASA_3117 gloB gloB amiB2 amiB2 acuC acuC BLASA_3519 BLASA_3519 BLASA_3789 BLASA_3789 BLASA_4154 BLASA_4154 add add cda cda folD2 folD2 purH purH BLASA_4228 BLASA_4228 BLASA_4513 BLASA_4513 BLASA_4559 BLASA_4559 purQ purQ dcd dcd mtaD mtaD BLASA_4809 BLASA_4809 cheB cheB BLASA_4996 BLASA_4996 argE2 argE2 amiC amiC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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BLASA_0103Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (198 aa)
tenAThiaminase-2; Function of strongly homologous gene; enzyme. (211 aa)
barBarbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. (367 aa)
arcAArginine deiminase; Function of strongly homologous gene; enzyme. (411 aa)
BLASA_0397LmbE family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (218 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (154 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (185 aa)
folEGTP cyclohydrolase I; Function of strongly homologous gene; enzyme. (205 aa)
BLASA_0598Conserved exported protein of unknown function, putative Enoyl-CoA hydratase domain; Homologs of previously reported genes of unknown function. (228 aa)
BLASA_0632Putative Acetylornithine deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (421 aa)
mshB1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (299 aa)
dapESuccinyl-diaminopimelate desuccinylase; Function of strongly homologous gene; enzyme. (370 aa)
pxpAPutative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (258 aa)
FCA1Cytosine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (182 aa)
BLASA_1131Carbamoylphosphate synthase large subunit (fragment); Gene remnant. (102 aa)
pncANicotinamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (190 aa)
amiBPutative amidase amiB2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the amidase family. (480 aa)
ribBARiboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (427 aa)
BLASA_1433Protein of unknown function; No homology to any previously reported sequences. (74 aa)
ribBA2Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (417 aa)
nylA6-aminohexanoate-cyclic-dimer hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the amidase family. (483 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (160 aa)
argEAcetylornithine deacetylase; Function of strongly homologous gene; enzyme. (397 aa)
fmdAAcetamidase/formamidase; Function of strongly homologous gene; enzyme. (341 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (282 aa)
BLASA_1997Putative uncharacterized protein; Homologs of previously reported genes of unknown function. (239 aa)
nadE2Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (610 aa)
BLASA_2226Homologs of previously reported genes of unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. (247 aa)
hisHImidazole glycerol phosphate synthase subunit hisH,glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (125 aa)
pdxTGlutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (230 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (429 aa)
def2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (181 aa)
ribDBifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (394 aa)
ribBA3Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (439 aa)
BLASA_2428Beta-lactamase-like Metallo-hydrolase; Function of strongly homologous gene; enzyme. (349 aa)
pyrGCTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (593 aa)
BLASA_2526Amidase; Function of strongly homologous gene; enzyme; Belongs to the amidase family. (468 aa)
BLASA_2541Amidohydrolase; Function of strongly homologous gene; enzyme. (527 aa)
BLASA_2542Amidohydrolase; Function of strongly homologous gene; enzyme. (545 aa)
folDBifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
purUFormyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa)
BLASA_2628Conserved exported protein of unknown function, putative Beta-lactamase domain; Homologs of previously reported genes of unknown function. (305 aa)
BLASA_2653Putative amidohydrolase ytcJ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (514 aa)
dopPup deamidase; Function of strongly homologous gene; enzyme. (501 aa)
BLASA_2775Homologs of previously reported genes of unknown function. (268 aa)
ribBA4Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (428 aa)
BLASA_2930Homologs of previously reported genes of unknown function. (258 aa)
BLASA_2972Cytosine deaminase-like metal-dependent hydrolase; Function of strongly homologous gene; enzyme. (506 aa)
BLASA_2986Putative cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (330 aa)
ansAPutative L-asparaginase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (322 aa)
BLASA_3117Polysaccharide deacetylase; Function of strongly homologous gene; enzyme. (295 aa)
gloBHydroxyacylglutathione hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (313 aa)
amiB2Amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; Function of strongly homologous gene; enzyme. (465 aa)
acuCAcetoin dehydrogenase; Function of strongly homologous gene; enzyme. (393 aa)
BLASA_3519Predicted glutamine amidotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (228 aa)
BLASA_3789Amidohydrolase; Function of strongly homologous gene; enzyme. (370 aa)
BLASA_4154N-acetylmuramoyl-L-alanine amidase; Function of strongly homologous gene; enzyme. (967 aa)
addAdenosine deaminase; Function of strongly homologous gene; enzyme. (357 aa)
cdaCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (139 aa)
folD2Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (516 aa)
BLASA_4228Uncharacterized LmbE-like protein; Function of strongly homologous gene; enzyme. (246 aa)
BLASA_4513L-asparaginase II; Function of strongly homologous gene; enzyme. (312 aa)
BLASA_4559Ring-opening amidohydrolase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. (367 aa)
purQPhosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (223 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (199 aa)
mtaD5-methylthioadenosine/S-adenosylhomocysteine deaminase; Function of strongly homologous gene; enzyme. (432 aa)
BLASA_4809Putative Creatininase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (231 aa)
cheBChemotaxis response regulator protein CheB-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (374 aa)
BLASA_4996Conserved protein of unknown function, putative transcription activator domain; Homologs of previously reported genes of unknown function. (219 aa)
argE2Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase; Function of strongly homologous gene; enzyme. (362 aa)
amiCN-acetylmuramoyl-L-alanine amidase; Function of strongly homologous gene; enzyme. (375 aa)
Your Current Organism:
Blastococcus saxobsidens
NCBI taxonomy Id: 1146883
Other names: B. saxobsidens DD2, Blastococcus saxobsidens DD2, Blastococcus saxobsidens str. DD2, Blastococcus saxobsidens strain DD2
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