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| | BLASA_4996 | Conserved protein of unknown function, putative transcription activator domain; Homologs of previously reported genes of unknown function. (219 aa) |
| | BLASA_5009 | Homologs of previously reported genes of unknown function. (145 aa) |
| | dinB2 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (476 aa) |
| | BLASA_5034 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (871 aa) |
| | BLASA_5056 | Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. (193 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (412 aa) |
| | priA2 | Putative primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (653 aa) |
| | ribD | Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (394 aa) |
| | ribE | Riboflavin synthase alpha chain; Function of strongly homologous gene; enzyme. (223 aa) |
| | cobO | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (204 aa) |
| | BLASA_1256 | Cobaltochelatase subunit; Function of strongly homologous gene; enzyme. (684 aa) |
| | cobL | Precorrin-6Y C(5,15)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (409 aa) |
| | cobM | Precorrin-4 C(11)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. (246 aa) |
| | cbiD | cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (364 aa) |
| | cobB | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (467 aa) |
| | cobK | Precorrin-6A reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (251 aa) |
| | cobIJ | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. (498 aa) |
| | cobH | Precorrin-8X methylmutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (206 aa) |
| | thyX | Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa) |
| | thyA | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (268 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (177 aa) |
| | BLASA_3651 | Glyoxalase/bleomycin resistance protein/dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (140 aa) |
| | BLASA_3515 | Homologs of previously reported genes of unknown function. (140 aa) |
| | BLASA_3486 | Homologs of previously reported genes of unknown function. (337 aa) |
| | BLASA_3472 | Homologs of previously reported genes of unknown function. (114 aa) |
| | BLASA_3471 | Homologs of previously reported genes of unknown function. (70 aa) |
| | ribBA3 | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (439 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (176 aa) |
| | BLASA_2391 | Predicted nucleoside-diphosphate sugar epimerase; Homologs of previously reported genes of unknown function; enzyme. (248 aa) |
| | BLASA_3429 | Putative L-aspartate oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (418 aa) |
| | BLASA_3389 | Homologs of previously reported genes of unknown function. (101 aa) |
| | elaA | Putative acetyltransferase; Function of strongly homologous gene; putative enzyme. (151 aa) |
| | BLASA_3360 | Putative Dihydrofolate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (225 aa) |
| | sigB | RNA polymerase sigma factor sigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (328 aa) |
| | BLASA_3326 | Homologs of previously reported genes of unknown function. (120 aa) |
| | BLASA_3320 | Protein of unknown function; No homology to any previously reported sequences. (202 aa) |
| | BLASA_3319 | Putative Dihydrofolate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (207 aa) |
| | rpoD | RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (450 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (168 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa) |
| | BLASA_3275 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (466 aa) |
| | BLASA_3273 | Chlorite dismutase; Function of strongly homologous gene; enzyme. (239 aa) |
| | BLASA_3263 | DNA polymerase LigD, polymerase domain; Function of strongly homologous gene; enzyme. (355 aa) |
| | BLASA_3258 | Putative bifunctional deaminase-reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (251 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (310 aa) |
| | BLASA_3223 | Cytochrome oxidase assembly protein; Function of strongly homologous gene; cell process. (314 aa) |
| | BLASA_3199 | Putative Sirohydrochlorin cobaltochelatase domains, cbiX family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (233 aa) |
| | BLASA_3190 | Homologs of previously reported genes of unknown function. (318 aa) |
| | BLASA_3144 | Phosphoribulokinase/uridine kinase; Function of strongly homologous gene; enzyme. (231 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (390 aa) |
| | sigF | RNA polymerase sigma-F factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. (318 aa) |
| | BLASA_3097 | DNA polymerase LigD, polymerase domain; Function of strongly homologous gene; enzyme. (301 aa) |
| | pdxY | Pyridoxamine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyridoxine kinase family. (283 aa) |
| | BLASA_2892 | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (277 aa) |
| | ligB2 | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (515 aa) |
| | BLASA_2868 | Homologs of previously reported genes of unknown function. (201 aa) |
| | BLASA_2866 | DNA polymerase I family protein with 3'-5'-exonuclease and polymerase domains; Function of strongly homologous gene; enzyme. (553 aa) |
| | ribBA4 | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (428 aa) |
| | BLASA_2811 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (417 aa) |
| | xyoA | Putative xylitol oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (437 aa) |
| | BLASA_2784 | Homologs of previously reported genes of unknown function. (427 aa) |
| | tdk | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (251 aa) |
| | coaA | Pantothenate kinase; Function of strongly homologous gene; enzyme. (317 aa) |
| | purU | Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa) |
| | folD | Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | folP3 | Dihydropteroate synthase 1; Function of strongly homologous gene; enzyme. (281 aa) |
| | BLASA_2569 | Phenylacetic acid-responsive transcriptional repressor; Function of strongly homologous gene; regulator. (280 aa) |
| | BLASA_2568 | Putative acid-thiol ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (535 aa) |
| | paaX | Phenylacetic acid-responsive transcriptional repressor; Function of strongly homologous gene; regulator. (281 aa) |
| | badA | Benzoate-CoA ligase; Function of strongly homologous gene; enzyme. (540 aa) |
| | cmk | Cytidylate kinase; Function of strongly homologous gene; enzyme. (229 aa) |
| | pyrG | CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (593 aa) |
| | BLASA_2485 | Thiamin pyrophosphokinase; Function of strongly homologous gene; enzyme. (395 aa) |
| | ppnK | Putative inorganic polyphosphate/ATP-NAD kinase 2; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (350 aa) |
| | BLASA_2429 | Homologs of previously reported genes of unknown function. (165 aa) |
| | BLASA_2427 | Uridine kinase; Function of strongly homologous gene; enzyme. (186 aa) |
| | BLASA_2426 | Uroporphyrinogen-III synthase; Function of strongly homologous gene; enzyme. (346 aa) |
| | BLASA_2425 | Uroporphyrinogen-III synthase (end); Function of strongly homologous gene; enzyme. (80 aa) |
| | BLASA_1264 | Homologs of previously reported genes of unknown function. (214 aa) |
| | cobN | Aerobic cobaltochelatase subunit cobN; Function of strongly homologous gene; enzyme. (1206 aa) |
| | acsA2 | Acetoacetyl-coenzyme A synthetase; Function of strongly homologous gene; enzyme. (683 aa) |
| | BLASA_1299 | RNA polymerase sigma factor, sigma-70 family (fragment); Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa) |
| | nadC | Quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family. (299 aa) |
| | nadB | L-aspartate oxidase (Quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate. (568 aa) |
| | nadA | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (337 aa) |
| | BLASA_1343 | RNA polymerase, sigma subunit, ECF family; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (327 aa) |
| | ribBA | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (427 aa) |
| | BLASA_1408 | Homologs of previously reported genes of unknown function. (146 aa) |
| | BLASA_1426 | Homologs of previously reported genes of unknown function. (183 aa) |
| | ribBA2 | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (417 aa) |
| | folC | Folylpolyglutamate synthase/dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. (451 aa) |
| | ndk | Nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (136 aa) |
| | proB | Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa) |
| | proA | Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (240 aa) |
| | selA | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (441 aa) |
| | hemN | Oxygen-independent coproporphyrinogen-III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (412 aa) |
| | dnaG2 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (628 aa) |
| | BLASA_1649 | Putative metallo-beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (201 aa) |
| | cobT | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Function of strongly homologous gene; enzyme. (566 aa) |
| | cobU | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (171 aa) |
| | cobS | Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (269 aa) |
| | BLASA_1819 | Homologs of previously reported genes of unknown function. (197 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (282 aa) |
| | nadE2 | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (610 aa) |
| | guaA | Putative GMP synthase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (242 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (328 aa) |
| | BLASA_2099 | Putative cobalamin biosynthesis protein cobU; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (269 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa) |
| | polC | DNA-directed DNA polymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (593 aa) |
| | BLASA_2192 | DNA polymerase III, alpha subunit; Function of strongly homologous gene; enzyme; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1268 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (407 aa) |
| | BLASA_2249 | Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (151 aa) |
| | dnaE2 | DNA polymerase III subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1178 aa) |
| | priA | Phosphoribosyl isomerase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (243 aa) |
| | trpE | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (512 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the TrpC family. (269 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (449 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (915 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (182 aa) |
| | sigK | RNA polymerase sigma factor, ECF family; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (217 aa) |
| | pdxS | Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (302 aa) |
| | pdxT | Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (230 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (195 aa) |
| | relA | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (817 aa) |
| | nusB | Transcription antitermination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (135 aa) |
| | pyrB | Aspartate carbamoyltransferase (catalytic subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (429 aa) |
| | cbiM | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (230 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Function of strongly homologous gene; enzyme; Belongs to the CarA family. (388 aa) |
| | carB | Carbamoyl phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. (1109 aa) |
| | BLASA_2364 | Dihydroorotate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (457 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Function of strongly homologous gene; enzyme; Belongs to the OMP decarboxylase family. Type 2 subfamily. (296 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (87 aa) |
| | cbiN | Cobalt transport protein cbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (102 aa) |
| | cbiG | Cobalamin biosynthesis protein CbiG; Function of strongly homologous gene; cell process. (154 aa) |
| | cobA | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. (411 aa) |
| | BLASA_1212 | Protein of unknown function, putative Glutathione synthetase ATP-binding domain; No homology to any previously reported sequences. (473 aa) |
| | BLASA_1171 | DNA primase, small subunit; Function of strongly homologous gene; enzyme. (314 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (427 aa) |
| | pncA | Nicotinamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (190 aa) |
| | BLASA_1092 | Homologs of previously reported genes of unknown function. (118 aa) |
| | sigC2 | RNA polymerase sigma-C factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | BLASA_1044 | Adenylate cyclase, family protein 3; Function of strongly homologous gene; enzyme. (508 aa) |
| | BLASA_0972 | RNA polymerase, sigma subunit, ECF family; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa) |
| | BLASA_0928 | Pterin-4-alpha-carbinolamine dehydratase; Function of strongly homologous gene; enzyme. (97 aa) |
| | BLASA_0920 | Putative spheroidene monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (241 aa) |
| | BLASA_0908 | Putative dihydrofolate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (179 aa) |
| | BLASA_0859 | Homologs of previously reported genes of unknown function. (367 aa) |
| | BLASA_0852 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. (320 aa) |
| | fliI | Flagellum-specific ATP synthase; Function of strongly homologous gene; enzyme. (436 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (386 aa) |
| | BLASA_0055 | RNA polymerase ECF-subfamily sigma factor; Function of strongly homologous gene; enzyme; Belongs to the sigma-70 factor family. ECF subfamily. (210 aa) |
| | BLASA_0084 | Competence/damage-inducible molybdopterin binding CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family. (427 aa) |
| | thiE | Thiamine monophosphate synthase; Function of strongly homologous gene; enzyme. (200 aa) |
| | thiG | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (277 aa) |
| | thiS | Thiamine biosynthesis protein ThiS; Function of strongly homologous gene; factor. (66 aa) |
| | thiO | Glycine oxidase; Function of strongly homologous gene; enzyme. (370 aa) |
| | thiE2 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (208 aa) |
| | BLASA_0103 | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (198 aa) |
| | tenA | Thiaminase-2; Function of strongly homologous gene; enzyme. (211 aa) |
| | thiD | Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (284 aa) |
| | BLASA_0177 | RNA polymerase sigma factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (216 aa) |
| | sigE | RNA polymerase sigma-E factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa) |
| | hpnH | Hopanoid biosynthesis associated radical SAM protein HpnH; Function of strongly homologous gene; enzyme. (551 aa) |
| | BLASA_0219 | Putative acetyl-CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (513 aa) |
| | BLASA_0257 | IMP dehydrogenase family protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (476 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (433 aa) |
| | folP | Dihydropteroate synthase 2; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (286 aa) |
| | rkpK | UDP-glucose 6-dehydrogenase; Function of strongly homologous gene; enzyme. (439 aa) |
| | rkpK2 | UDP-glucose 6-dehydrogenase; Function of strongly homologous gene; enzyme. (439 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (189 aa) |
| | algD | GDP-mannose 6-dehydrogenase; Function of strongly homologous gene; enzyme. (422 aa) |
| | hldE | Bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (471 aa) |
| | BLASA_0452 | Homologs of previously reported genes of unknown function. (543 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (789 aa) |
| | acsA | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa) |
| | BLASA_0532 | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. (397 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (505 aa) |
| | cobD | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (337 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | glmU | Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (503 aa) |
| | moeA | Molybdopterin biosynthesis protein moeA 1; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (474 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Function of strongly homologous gene; enzyme. (513 aa) |
| | BLASA_0732 | Homologs of previously reported genes of unknown function. (163 aa) |
| | sigC | RNA polymerase sigma-C factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa) |
| | BLASA_0693 | Homologs of previously reported genes of unknown function. (209 aa) |
| | pdxH | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa) |
| | BLASA_0627 | Homologs of previously reported genes of unknown function. (213 aa) |
| | BLASA_0614 | Homologs of previously reported genes of unknown function. (145 aa) |
| | BLASA_0604 | Transcriptional regulator, CarD family; Function of strongly homologous gene; regulator. (160 aa) |
| | coaX | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (268 aa) |
| | folK | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Function of strongly homologous gene; enzyme. (167 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (131 aa) |
| | folP2 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (284 aa) |
| | folE | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. (205 aa) |
| | hpt | Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (194 aa) |
| | dnaX2 | DNA polymerase III, delta prime subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (399 aa) |
| | atpA | ATP synthase, alpha subunit, F1 sector; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (545 aa) |
| | atpG | ATP synthase, gamma subunit, F1 sector; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (323 aa) |
| | atpD | ATP synthase, beta subunit, F1 sector; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (480 aa) |
| | atpC | ATP synthase, epsilon subunit, F1 sector; Produces ATP from ADP in the presence of a proton gradient across the membrane. (129 aa) |
| | BLASA_3914 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Cob(I)alamin adenosyltransferase family. (206 aa) |
| | BLASA_3903 | Homologs of previously reported genes of unknown function. (86 aa) |
| | BLASA_3842 | Putative GMP synthase family protein (glutamine-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (242 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (346 aa) |
| | BLASA_3818 | Homologs of previously reported genes of unknown function. (208 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | BLASA_3797 | ABC-type Co2+ transport system, permease component; Function of strongly homologous gene; transporter. (104 aa) |
| | cbiM2 | Cobalt membrane transport protein CbiM; Function of strongly homologous gene; transporter. (234 aa) |
| | whiG | RNA polymerase sigma factor whiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (266 aa) |
| | pyrH | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. (256 aa) |
| | nusA | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. (383 aa) |
| | BLASA_3737 | Putative 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (224 aa) |
| | ribF | Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase; Function of strongly homologous gene; enzyme; Belongs to the ribF family. (322 aa) |
| | atpH | ATP synthase, delta subunit, F1 sector; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (290 aa) |
| | atpF | ATP synthase, subunit b, F0 sector; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (186 aa) |
| | atpE | ATP synthase, subunit c, F0 sector; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (76 aa) |
| | atpB | ATP synthase, subunit a, F0 sector; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (275 aa) |
| | rho | Transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (714 aa) |
| | cya | Family 3 adenylate cyclase; Function of strongly homologous gene; enzyme. (354 aa) |
| | rpoE | RNA polymerase sigma-E factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the sigma-70 factor family. ECF subfamily. (230 aa) |
| | BLASA_4052 | Homologs of previously reported genes of unknown function. (184 aa) |
| | manA | Mannose-6-phosphate isomerase, class I; Function of strongly homologous gene; enzyme. (391 aa) |
| | rmlD | dTDP-4-dehydrorhamnose reductase (fragment); Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (281 aa) |
| | strM | dTDP-4-dehydrorhamnose 3,5-epimerase; Function of strongly homologous gene; enzyme. (201 aa) |
| | BLASA_4138 | Homologs of previously reported genes of unknown function. (265 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (171 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (377 aa) |
| | upp | Uracil phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UPRTase family. (210 aa) |
| | add | Adenosine deaminase; Function of strongly homologous gene; enzyme. (357 aa) |
| | folD2 | Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (516 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (191 aa) |
| | guaA2 | GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | BLASA_4236 | Putative inosine monophosphate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (378 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (504 aa) |
| | moaE | Molybdopterin molybdenumtransferase 2; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (400 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (157 aa) |
| | moaB | Molybdopterin adenylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (164 aa) |
| | fdhD | Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (266 aa) |
| | BLASA_4265 | Molybdopterin-guanine dinucleotide synthase; Function of strongly homologous gene; enzyme. (196 aa) |
| | rpoA | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (358 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (204 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1301 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1169 aa) |
| | nusG | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (302 aa) |
| | BLASA_4464 | Homologs of previously reported genes of unknown function. (70 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase; Function of strongly homologous gene; enzyme. (455 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family. (344 aa) |
| | hemD | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. (514 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (328 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (459 aa) |
| | BLASA_4480 | RNA polymerase, sigma-24 subunit, ECF subfamily; Function of strongly homologous gene; enzyme; Belongs to the sigma-70 factor family. ECF subfamily. (259 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | BLASA_4524 | Conserved protein of unknown function; May play a role in the intracellular transport of hydrophobic ligands. (177 aa) |
| | accD2 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Function of strongly homologous gene; enzyme. (515 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (353 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (512 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (788 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (223 aa) |
| | purS | Phosphoribosylformylglycinamidine synthetase, PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is tho [...] (90 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Function of strongly homologous gene; enzyme; Belongs to the SAICAR synthetase family. (292 aa) |
| | purB | Adenylosuccinate lyase; Function of strongly homologous gene; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. (427 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (199 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (379 aa) |
| | acsA1 | Acetoacetyl-coenzyme A synthetase; Function of strongly homologous gene; enzyme. (668 aa) |
| | BLASA_4789 | Conserved protein of unknown function, putative Radical SAM domain; Homologs of previously reported genes of unknown function. (483 aa) |
| | BLASA_4809 | Putative Creatininase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (231 aa) |
| | BLASA_4812 | Putative Fe-S oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (408 aa) |
| | BLASA_4834 | 2,5-didehydrogluconate reductase; Function of strongly homologous gene; enzyme. (275 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (351 aa) |
| | moaD2 | Molybdenum cofactor biosynthesis protein D (MoaD) / thiamineS; Function of strongly homologous gene; cell process. (78 aa) |
| | moaE2 | Molybdopterin synthase subunit; Function of strongly homologous gene; cell process. (136 aa) |
