node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLASA_1610 | deoA | BLASA_1610 | BLASA_4193 | Homologs of previously reported genes of unknown function. | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.446 |
BLASA_1997 | mshB | BLASA_1997 | BLASA_0939 | Putative uncharacterized protein; Homologs of previously reported genes of unknown function. | 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.431 |
BLASA_4228 | mca | BLASA_4228 | BLASA_0803 | Uncharacterized LmbE-like protein; Function of strongly homologous gene; enzyme. | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.551 |
apt | deoA | BLASA_2329 | BLASA_4193 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.530 |
apt | hpt | BLASA_2329 | BLASA_0575 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.970 |
apt | punA | BLASA_2329 | BLASA_4177 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.959 |
cda | deoA | BLASA_4194 | BLASA_4193 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.999 |
cda | punA | BLASA_4194 | BLASA_4177 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.967 |
cda | tdk | BLASA_4194 | BLASA_2646 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.929 |
cysS2 | mca | BLASA_2691 | BLASA_0803 | cysteinyl-tRNA synthetase 2; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.901 |
cysS2 | mshA | BLASA_2691 | BLASA_4505 | cysteinyl-tRNA synthetase 2; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | UDP-Glycosyltransferase/glycogen phosphorylase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.506 |
cysS2 | mshB | BLASA_2691 | BLASA_0939 | cysteinyl-tRNA synthetase 2; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.926 |
cysS2 | mshD | BLASA_2691 | BLASA_4534 | cysteinyl-tRNA synthetase 2; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.955 |
deoA | BLASA_1610 | BLASA_4193 | BLASA_1610 | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Homologs of previously reported genes of unknown function. | 0.446 |
deoA | apt | BLASA_4193 | BLASA_2329 | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.530 |
deoA | cda | BLASA_4193 | BLASA_4194 | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.999 |
deoA | hpt | BLASA_4193 | BLASA_0575 | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.581 |
deoA | punA | BLASA_4193 | BLASA_4177 | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.975 |
deoA | tdk | BLASA_4193 | BLASA_2646 | Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.942 |
hpt | apt | BLASA_0575 | BLASA_2329 | Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.970 |