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fbaA, fbaA, pykF pykF fbpI fbpI ppsA ppsA eno eno ddh ddh ppc ppc pfkA pfkA deoC deoC fda fda talB talB pfkA-2 pfkA-2 tktA tktA pgk pgk AIE75416.1 AIE75416.1 pgi pgi yibO yibO gap1 gap1 tpi tpi fbpII fbpII pykF-2 pykF-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
fbaA,Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pykFPyruvate kinase; Sly1029100; Belongs to the pyruvate kinase family. (591 aa)
fbpIFructose-1,6-bisphosphatase, GlpX type / Sedoheptulose-1,7-bisphosphatase; Sly2000720; Belongs to the FBPase class 2 family. (345 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
ddhD-lactate dehydrogenase; Sly1023370; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1034 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (384 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa)
fdaFructose-bisphosphate aldolase class I; Sly1016170; Belongs to the class I fructose-bisphosphate aldolase family. (299 aa)
talBTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (391 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa)
tktATransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (670 aa)
pgkPhosphoglycerate kinase; Sly1009160; Belongs to the phosphoglycerate kinase family. (400 aa)
AIE75416.1Xylulose-5-phosphate phosphoketolase; Sly1007360. (805 aa)
pgiGlucose-6-phosphate isomerase; Sly1006750; Belongs to the GPI family. (531 aa)
yibO2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (497 aa)
gap1NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Sly1006220; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (242 aa)
fbpIIFructose-1,6-bisphosphatase, type I; Sly1020910; Belongs to the FBPase class 1 family. (347 aa)
pykF-2Pyruvate kinase; Sly1019970; Belongs to the pyruvate kinase family. (473 aa)
Your Current Organism:
Synechocystis sp. PCC6714
NCBI taxonomy Id: 1147
Other names: Aphanocapsa sp. (strain 5.3A), Aphanocapsa sp. 5-3A, Aphanocapsa sp. 5.3A, S. sp. PCC 6714, Synechocystis sp. (ATCC 27178), Synechocystis sp. (PCC 6714), Synechocystis sp. (strain PCC 6714), Synechocystis sp. ATCC 27178, Synechocystis sp. PCC 6714, Synechocystis sp. SAG 92.79, Synechocystis sp. UTCC 98, Synechocystis sp. UTEX 2470
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