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fabZ fabZ rfbD rfbD leuD leuD eno eno yefA yefA aroC aroC fpg fpg dcoH dcoH trpA trpA AIE74658.1 AIE74658.1 AIE74869.1 AIE74869.1 vgb vgb cobA/hemD cobA/hemD AIE75129.1 AIE75129.1 AIE75143.1 AIE75143.1 hisB hisB nth nth thrC thrC icfA icfA trpB trpB ilvD ilvD dapA dapA hemB hemB aroB aroB murQ murQ nnrD nnrD mgsA mgsA pheA pheA acnB acnB fumC fumC AIE72589.1 AIE72589.1 aroQ aroQ ecaB ecaB rfbB rfbB leuC leuC AIE73624.1 AIE73624.1
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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gene co-occurrence
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fabZ(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (166 aa)
rfbDGDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (362 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
yefAGDP-mannose 4,6 dehydratase; Sly1023580. (317 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (363 aa)
fpgFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (287 aa)
dcoHPterin-4-alpha-carbinolamine dehydratase; Sly1017390. (52 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa)
AIE74658.1GDP-mannose 4,6-dehydratase; Sly1015470. (80 aa)
AIE74869.1O-succinylbenzoate synthase; Sly1013310; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (321 aa)
vgbPutative hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. (352 aa)
cobA/hemDUroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase; Sly1011940; Belongs to the precorrin methyltransferase family. (508 aa)
AIE75129.1Queuosine biosynthesis QueD, PTPS-I; Sly1010190. (129 aa)
AIE75143.1Porphobilinogen synthase; Sly1010050; Belongs to the ALAD family. (312 aa)
hisBImidazoleglycerol-phosphate dehydratase; Sly2001060. (210 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (215 aa)
thrCThreonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (382 aa)
icfACarbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (285 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (379 aa)
ilvDDihydroxy-acid dehydratase; Sly1007340; Belongs to the IlvD/Edd family. (563 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
hemBPorphobilinogen synthase; Sly1009110; Belongs to the ALAD family. (327 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (306 aa)
nnrDNAD(P)HX epimerase / NAD(P)HX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (530 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (433 aa)
pheAPrephenate dehydratase; Sly1000410. (299 aa)
acnBAconitate hydratase 2; Sly1002900; Belongs to the aconitase/IPM isomerase family. (868 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (455 aa)
AIE72589.1Fumarate hydratase class II; Sly1003850. (42 aa)
aroQ3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
ecaBCarbonic anhydrase; Sly3001030. (234 aa)
rfbBdTDP-glucose 4,6-dehydratase; Sly3001360; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (342 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
AIE73624.1Hypothetical protein; Sly2000650. (164 aa)
Your Current Organism:
Synechocystis sp. PCC6714
NCBI taxonomy Id: 1147
Other names: Aphanocapsa sp. (strain 5.3A), Aphanocapsa sp. 5-3A, Aphanocapsa sp. 5.3A, S. sp. PCC 6714, Synechocystis sp. (ATCC 27178), Synechocystis sp. (PCC 6714), Synechocystis sp. (strain PCC 6714), Synechocystis sp. ATCC 27178, Synechocystis sp. PCC 6714, Synechocystis sp. SAG 92.79, Synechocystis sp. UTCC 98, Synechocystis sp. UTEX 2470
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