STRINGSTRING
AIE75143.1 AIE75143.1 cobA/hemD cobA/hemD chlD chlD pys, pys, AIE74629.1 AIE74629.1 pds, pds, crtQ-2 crtQ-2 crtH crtH hemF hemF AIE74264.1 AIE74264.1 ctaB ctaB chlB chlB hemC hemC chlP chlP ycf59 ycf59 chlL chlL chlN chlN chlI chlI cobA cobA AIE73382.1 AIE73382.1 hemN hemN AT103 AT103 bchE bchE chlG chlG hemL hemL por por hemA hemA hemH, hemH, bchB bchB chlH chlH AIE75558.1 AIE75558.1 AIE75522.1 AIE75522.1 hemE hemE hemB hemB chlM chlM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIE75143.1Porphobilinogen synthase; Sly1010050; Belongs to the ALAD family. (312 aa)
cobA/hemDUroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase; Sly1011940; Belongs to the precorrin methyltransferase family. (508 aa)
chlDProtoporphyrin IX Mg-chelatase subunit D; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (676 aa)
pys,Phytoene synthase; Sly1014130. (337 aa)
AIE74629.1Protoporphyrinogen IX oxidase, novel form, HemJ; Sly1015760. (193 aa)
pds,Phytoene desaturase, pro-zeta-carotene producing; Sly1014140. (469 aa)
crtQ-2Pro-zeta-carotene desaturase, prolycopene producing; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'. (489 aa)
crtHCarotenoid cis-trans isomerase; Sly1017130. (501 aa)
hemFCoproporphyrinogen III oxidase, aerobic; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (340 aa)
AIE74264.1Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA; Sly1019290. (313 aa)
ctaBHeme O synthase, protoheme IX farnesyltransferase COX10-CtaB; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (316 aa)
chlBLight-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (508 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (299 aa)
chlPGeranylgeranyl hydrogenase BchP; Sly1025340. (407 aa)
ycf59Mg protoporphyrin IX monomethyl ester oxidative cyclase (aerobic); Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (358 aa)
chlLLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein ChlL; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (306 aa)
chlNLight-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (469 aa)
chlIProtoporphyrin IX Mg-chelatase subunit I; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (357 aa)
cobAUroporphyrinogen-III methyltransferase; Sly1029500; Belongs to the precorrin methyltransferase family. (258 aa)
AIE73382.1Phytoene desaturase; Sly1029930. (650 aa)
hemNCoproporphyrinogen III oxidase, oxygen-independent; Sly1030200; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (466 aa)
AT103Mg protoporphyrin IX monomethyl ester oxidative cyclase (aerobic); Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (358 aa)
bchEMg-protoporphyrin IX monomethyl ester oxidative cyclase (anaerobic); Sly3001590. (499 aa)
chlGChlorophyll a synthase ChlG; Sly3001130. (324 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Sly2002080. (433 aa)
porLight-dependent protochlorophyllide reductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (322 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (427 aa)
hemH,Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (387 aa)
bchBProtochlorophyllide reductase BchB subunit; Sly3000120. (55 aa)
chlHProtoporphyrin IX Mg-chelatase subunit H; Sly1004620. (1332 aa)
AIE75558.1PUCC protein:PUCC protein; Sly1005980. (484 aa)
AIE75522.1Hypothetical protein; Sly1006350. (58 aa)
hemEUroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa)
hemBPorphobilinogen synthase; Sly1009110; Belongs to the ALAD family. (327 aa)
chlMMg-protoporphyrin O-methyltransferase; Sly1009580. (230 aa)
Your Current Organism:
Synechocystis sp. PCC6714
NCBI taxonomy Id: 1147
Other names: Aphanocapsa sp. (strain 5.3A), Aphanocapsa sp. 5-3A, Aphanocapsa sp. 5.3A, S. sp. PCC 6714, Synechocystis sp. (ATCC 27178), Synechocystis sp. (PCC 6714), Synechocystis sp. (strain PCC 6714), Synechocystis sp. ATCC 27178, Synechocystis sp. PCC 6714, Synechocystis sp. SAG 92.79, Synechocystis sp. UTCC 98, Synechocystis sp. UTEX 2470
Server load: medium (44%) [HD]