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purH purH purK purK sll1108 sll1108 pyrD pyrD pykF-2 pykF-2 purL-2 purL-2 purM purM pyrR pyrR carB carB purN purN fmt fmt guaA guaA clpC clpC umpS umpS infB infB hrcA hrcA ackA ackA htrA htrA mgtE mgtE ndkR ndkR pyrH pyrH purB purB purD purD pyrB pyrB pyrG pyrG thl thl sll1459 sll1459 pyrF pyrF pykF pykF purC purC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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textmining
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purHPhosphoribosyl aminoimidazole carboxy formyl formyltransferase/inosinemonophosphate cyclohydrolase; ORF_ID:slr0597. (553 aa)
purKPhosphoribosyl aminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (388 aa)
sll11085'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (275 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (381 aa)
pykF-2Pyruvate kinase; ORF_ID:sll0587. (483 aa)
purL-2Phosphoribosyl formylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (224 aa)
purMPhosphoribosyl formylglycinamidine cyclo-ligase; ORF_ID:slr0838; gene:purM or purG. (341 aa)
pyrRPyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. (178 aa)
carBCarbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. (1105 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (217 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (330 aa)
guaAGMP synthetase; Catalyzes the synthesis of GMP from XMP. (542 aa)
clpCATP-dependent Clp protease regulatory subunit; ORF_ID:sll0020; Belongs to the ClpA/ClpB family. (821 aa)
umpSUridine 5'-monophosphate synthase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (198 aa)
infBInitiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1001 aa)
hrcACIRCE binding repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (378 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (413 aa)
htrASerine protease; A putative protease, its function overlaps that of the related putative proteases HhoA and HhoB. Belongs to the peptidase S1C family. (452 aa)
mgtEMg2+ transporter; Acts as a magnesium transporter. (463 aa)
ndkRNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (149 aa)
pyrHUridine monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (260 aa)
purBAdenylosuccinate lyase; ORF_ID:sll0421. (431 aa)
purDGlycinamide ribonucleotide synthetase; ORF_ID:slr1159. (419 aa)
pyrBAspartate carbamoyltransferase; ORF_ID:slr1476; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (331 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (552 aa)
thlAcetyl coenzyme A acetyltransferase (thiolase); When expressed in E.coli with Synechocystis PhaB, PhaC and PhaE confers the ability to synthesize up to 12% (w/w) poly(3- hydroxybutyrate) (PHB) depending on the carbon source. (409 aa)
sll1459Putative 5'-nucleotidase alr3139; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (225 aa)
pyrFOrotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (231 aa)
pykFPyruvate kinase; ORF_ID:sll1275; In the C-terminal section; belongs to the PEP-utilizing enzyme family. (591 aa)
purCPhosphoribosyl aminoidazole succinocarboxamide synthetase; ORF_ID:slr1226; Belongs to the SAICAR synthetase family. (264 aa)
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B
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