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ftsZ ftsZ divIVA divIVA spoVS spoVS spoVG spoVG ftsL ftsL divIB divIB ftsA ftsA noc noc ftsE ftsE ftsX ftsX minJ minJ ezrA ezrA yshA yshA engB engB minC minC minD minD spo0A spo0A ypbR ypbR yneA yneA ftsZ3 ftsZ3 ylmF ylmF
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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textmining
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ftsZTubulin beta-1 chain Beta-1-tubulin; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (382 aa)
divIVASeptum site-determining protein divIVA. (164 aa)
spoVSStage V sporulation protein S. (86 aa)
spoVGPutative septation protein SpoVG; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. (97 aa)
ftsLCell division protein; Essential cell division protein; Belongs to the FtsL family. (117 aa)
divIBCell division initiation protein DivIB; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (262 aa)
ftsAChaperone protein dnaK Heat shock protein 70; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (437 aa)
nocSpo0J-like DNA-binding protein; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family. (283 aa)
ftsEMethionine import ATP-binding protein metN; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
ftsXMacrolide export ATP-binding/permease protein macB; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (296 aa)
minJTopological determinant of cell division. (396 aa)
ezrASeptation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (563 aa)
yshACell division protein zapA Z ring-associated protein zapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (85 aa)
engBPutative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (195 aa)
minCPutative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (226 aa)
minDPutative septum site-determining protein minD. (269 aa)
spo0AStage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (266 aa)
ypbRPutative protein ypbR. (1193 aa)
yneACell division suppressor protein yneA; Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery; Belongs to the YneA family. (103 aa)
ftsZ3Cell division protein FtsZ. (370 aa)
ylmFCell division protein sepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (152 aa)
Your Current Organism:
Bacillus velezensis YAUB9601Y2
NCBI taxonomy Id: 1155777
Other names: B. velezensis YAU B9601-Y2, Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2, Bacillus methylotrophicus YAU B9601-Y2, Bacillus velezensis YAU B9601-Y2
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