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oppC oppC sigW sigW nusG1 nusG1 sigH sigH radA radA abrB abrB dnaA dnaA sodA sodA nusG3 nusG3 dfnG dfnG mleA mleA sigX sigX fenD fenD baeG baeG recA recA cheC cheC cheA cheA cheB cheB pyrE pyrE pyrK pyrK divIVA divIVA ftsZ ftsZ ftsA ftsA ftsL ftsL ylaH ylaH ogt ogt sigI sigI ykkB ykkB dppC dppC appC appC argD argD argB argB argJ argJ argC argC yisP yisP sigM sigM oppB oppB iolC iolC bglS bglS cydB cydB spsK spsK rocG rocG maeA maeA rbsA rbsA ftsE ftsE ftsX ftsX minJ minJ sigL sigL gapA gapA yvqL yvqL yuxK yuxK malS2 malS2 ytsJ ytsJ gapB gapB ilvH ilvH radC radC mreB mreB minC minC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
oppCDipeptide transport system permease protein dppC. (301 aa)
sigWRNA polymerase sigma-E factor Sigma-24; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
nusG1Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (177 aa)
sigHRNA polymerase sporulation-specific sigma factor; Belongs to the sigma-70 factor family. (206 aa)
radAradA-like DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (459 aa)
abrBTransition state regulatory protein AbrB. (94 aa)
dnaAChromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (446 aa)
sodASuperoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (201 aa)
nusG3Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (176 aa)
dfnGDifficidin synthase. (5203 aa)
mleAMalate dehydrogenase (oxaloacetate-decarboxylating). (437 aa)
sigXRNA polymerase sigma factor sigX; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
fenDFengycin synthetase. (3591 aa)
baeGhydroxymethylglutaryl-CoA synthase involved in bacillaene synthesis. (420 aa)
recAProtein recA Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (347 aa)
cheCChemotaxis protein CheC. (209 aa)
cheATwo-component system, chemotaxis family, sensor kinase CheA. (670 aa)
cheBChemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (355 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (210 aa)
pyrKDihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (256 aa)
divIVASeptum site-determining protein divIVA. (164 aa)
ftsZTubulin beta-1 chain Beta-1-tubulin; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (382 aa)
ftsAChaperone protein dnaK Heat shock protein 70; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (437 aa)
ftsLCell division protein; Essential cell division protein; Belongs to the FtsL family. (117 aa)
ylaHPutative membrane protein ylaH. (106 aa)
ogtmethylated-DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (165 aa)
sigIRNA polymerase sigma factor rpoD Sigma-43; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily. (248 aa)
ykkBAcetyltransferase, ribosomal protein N-acetylase. (181 aa)
dppCDipeptide transport system permease protein dppC. (315 aa)
appCOligopeptide transport system permease protein appC. (304 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (385 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (258 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (405 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa)
yisPPhytoene synthase. (246 aa)
sigMRNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
oppBGlutathione transport system permease protein gsiC. (318 aa)
iolC5-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP). (330 aa)
bglSEndo-beta-1,3-1,4 glucanase (licheninase). (243 aa)
cydBCydB. (357 aa)
spsKdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (282 aa)
rocGNAD-specific glutamate dehydrogenase (NAD-GDH) RocG; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (428 aa)
maeANAD-dependent malate dehydrogenase II. (565 aa)
rbsARibose ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (497 aa)
ftsEMethionine import ATP-binding protein metN; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
ftsXMacrolide export ATP-binding/permease protein macB; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (296 aa)
minJTopological determinant of cell division. (396 aa)
sigLRNA polymerase sigma-54 factor. (437 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
yvqLMolybdate/tungstate-binding protein. (265 aa)
yuxKPutative protein yuxK ORF2. (137 aa)
malS2Malate dehydrogenase. (560 aa)
ytsJMalate dehydrogenase (oxaloacetate-decarboxylating). (410 aa)
gapBGlyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
ilvHAcetolactate synthase 3 regulatory subunit. (172 aa)
radCradC-like DNA repair protein; Belongs to the UPF0758 family. (231 aa)
mreBChaperone protein dnaK Heat shock protein 70. (337 aa)
minCPutative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (226 aa)
Your Current Organism:
Bacillus velezensis YAUB9601Y2
NCBI taxonomy Id: 1155777
Other names: B. velezensis YAU B9601-Y2, Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2, Bacillus methylotrophicus YAU B9601-Y2, Bacillus velezensis YAU B9601-Y2
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