STRINGSTRING
sleB sleB spoIVA spoIVA citB citB nrdF nrdF nrdE1 nrdE1 cotE cotE recA recA sigG sigG spoIIGA spoIIGA sigM sigM asbF asbF phoD phoD cwlJ cwlJ sigW sigW spo0F spo0F spoIIE spoIIE spoIIP spoIIP aroE5 aroE5 spoIIIAH spoIIIAH sigK sigK spo0B spo0B phoR phoR phoP phoP citC citC citZ citZ epsB epsB epsA epsA hisG hisG ctpB ctpB secA secA spoIIQ spoIIQ spoIID2 spoIID2 spoIIR spoIIR spoIVB spoIVB spo0A spo0A sigF sigF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sleBSpore cortex-lytic enzyme. (289 aa)
spoIVAStage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (503 aa)
citBAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (875 aa)
nrdFRibonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (329 aa)
nrdE1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (700 aa)
cotESpore coat protein E. (181 aa)
recAProtein recA Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (347 aa)
sigGRNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (260 aa)
spoIIGAStage II sporulation protein GA (sporulation sigma-E factor processing peptidase); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. (309 aa)
sigMRNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
asbFProtein frlC. (262 aa)
phoDPhosphodiesterase/alkaline phosphatase D. (583 aa)
cwlJCell wall hydrolase. (142 aa)
sigWRNA polymerase sigma-E factor Sigma-24; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
spo0FTwo-component response regulator Spo0F. (124 aa)
spoIIEStage II sporulation protein E. (832 aa)
spoIIPStage II sporulation protein P. (397 aa)
aroE5Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa)
spoIIIAHStage III sporulation protein AH. (216 aa)
sigKRNA polymerase sigma-28 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (241 aa)
spo0BSporulation initiation phosphotransferase Spo0B. (192 aa)
phoRSensory box histidine kinase PhoR. (579 aa)
phoPAlkaline phosphatase synthesis transcriptional regulatory protein sphR. (239 aa)
citCIsocitrate dehydrogenase. (423 aa)
citZCitrate synthase; Belongs to the citrate synthase family. (372 aa)
epsBCapsular polysaccharide biosynthesis protein EpsB. (226 aa)
epsAPutative protein yveK. (235 aa)
hisGATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (213 aa)
ctpBCarboxyl-terminal processing protease; Belongs to the peptidase S41A family. (466 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (841 aa)
spoIIQSporulation protein SpoIIQ. (289 aa)
spoIID2Stage II sporulation protein D. (343 aa)
spoIIRStage II sporulation protein R. (226 aa)
spoIVBStage IV sporulation protein B. (426 aa)
spo0AStage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (266 aa)
sigFRNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (255 aa)
Your Current Organism:
Bacillus velezensis YAUB9601Y2
NCBI taxonomy Id: 1155777
Other names: B. velezensis YAU B9601-Y2, Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2, Bacillus methylotrophicus YAU B9601-Y2, Bacillus velezensis YAU B9601-Y2
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