STRINGSTRING
rplM rplM rplI rplI rpsF rpsF rplY rplY rpsT rpsT GCA_000953475_01016 GCA_000953475_01016 rpsK rpsK rpsD rpsD rpoA rpoA rplQ rplQ rplS rplS rpmA rpmA rplU rplU GCA_000953475_01285 GCA_000953475_01285 rpsA rpsA rpsR rpsR GCA_000953475_01480 GCA_000953475_01480 rplL rplL rplA rplA rplK rplK rpmG rpmG rplO rplO rplF rplF GCA_000953475_01696 GCA_000953475_01696 rplE rplE rplN rplN rpsQ rpsQ rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplD rplD rplC rplC fusA fusA rpsU rpsU rpmE rpmE rplT rplT GCA_000953475_02255 GCA_000953475_02255
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplMUnannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (143 aa)
rplIUnannotated protein; Binds to the 23S rRNA. (192 aa)
rpsFUnannotated protein; Binds together with S18 to 16S ribosomal RNA. (111 aa)
rplYUnannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (220 aa)
rpsTUnannotated protein; Binds directly to 16S ribosomal RNA. (89 aa)
GCA_000953475_01016Unannotated protein. (38 aa)
rpsKUnannotated protein; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (180 aa)
rpsDUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (202 aa)
rpoAUnannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (337 aa)
rplQUnannotated protein. (131 aa)
rplSUnannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (114 aa)
rpmAUnannotated protein; Belongs to the bacterial ribosomal protein bL27 family. (85 aa)
rplUUnannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (110 aa)
GCA_000953475_01285Unannotated protein. (63 aa)
rpsAUnannotated protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (558 aa)
rpsRUnannotated protein; Belongs to the bacterial ribosomal protein bS18 family. (83 aa)
GCA_000953475_01480Unannotated protein. (87 aa)
rplLUnannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (129 aa)
rplAUnannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (232 aa)
rplKUnannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
rpmGUnannotated protein; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
rplOUnannotated protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa)
rplFUnannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
GCA_000953475_01696Unannotated protein. (61 aa)
rplEUnannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (193 aa)
rplNUnannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (121 aa)
rpsQUnannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (97 aa)
rplPUnannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa)
rpsCUnannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (215 aa)
rplVUnannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (112 aa)
rpsSUnannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (91 aa)
rplBUnannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (283 aa)
rplDUnannotated protein; Forms part of the polypeptide exit tunnel. (218 aa)
rplCUnannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (216 aa)
fusAUnannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (723 aa)
rpsUUnannotated protein; Belongs to the bacterial ribosomal protein bS21 family. (61 aa)
rpmEUnannotated protein; Binds the 23S rRNA. (80 aa)
rplTUnannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (120 aa)
GCA_000953475_02255Unannotated protein. (71 aa)
Your Current Organism:
Methylacidiphilum fumariolicum
NCBI taxonomy Id: 1156937
Other names: M. fumariolicum SolV, Methylacidiphilum fumariolicum SolV, Methylacidiphilum fumariolicum str. SolV, Methylacidiphilum fumariolicum strain SolV
Server load: low (20%) [HD]