(49 nodes) Butanoate metabolism network (Aspergillus glaucus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L9VA67	Uncharacterized protein; Belongs to the TPP enzyme family. (513 aa)
	A0A1L9V3G2	Uncharacterized protein. (719 aa)
	A0A1L9V3T4	Uncharacterized protein. (100 aa)
	A0A1L9V414	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
	A0A1L9V4C2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
	A0A1L9V564	Uncharacterized protein. (696 aa)
	A0A1L9V5C6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (498 aa)
	A0A1L9V5H2	Uncharacterized protein; Belongs to the TPP enzyme family. (444 aa)
	A0A1L9V5M0	Uncharacterized protein. (296 aa)
	A0A1L9V9G3	Pyruvate carboxyltransferase domain-containing protein. (349 aa)
	A0A1L9VAZ0	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (550 aa)
	A0A1L9VD60	Acetolactate synthase. (677 aa)
	A0A1L9VEQ8	Uncharacterized protein. (347 aa)
	A0A1L9VES0	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (295 aa)
	A0A1L9VFE4	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (514 aa)
	A0A1L9VFH5	Uncharacterized protein. (599 aa)
	A0A1L9VFR5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (470 aa)
	A0A1L9VG04	Uncharacterized protein. (311 aa)
	A0A1L9VG50	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
	A0A1L9VI93	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (496 aa)
	A0A1L9VJH3	Pyruvate carboxyltransferase domain-containing protein. (327 aa)
	A0A1L9VJS2	Uncharacterized protein. (294 aa)
	A0A1L9VK66	Aldedh domain-containing protein. (494 aa)
	A0A1L9VKM1	Uncharacterized protein; Belongs to the TPP enzyme family. (490 aa)
	A0A1L9VLD1	AMP-binding domain-containing protein. (676 aa)
	A0A1L9VLV2	Uncharacterized protein. (312 aa)
	A0A1L9VMP6	Uncharacterized protein. (261 aa)
	A0A1L9VNU5	Uncharacterized protein. (1790 aa)
	A0A1L9VP00	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)
	A0A1L9VP34	Acetolactate synthase. (692 aa)
	A0A1L9VQG4	Uncharacterized protein. (143 aa)
	A0A1L9VRA3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	A0A1L9VRD2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (506 aa)
	A0A1L9VRG5	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	A0A1L9VT16	ACT domain-containing protein. (326 aa)
	A0A1L9VTP1	Uncharacterized protein. (264 aa)
	A0A1L9VTU1	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (495 aa)
	A0A1L9VUT1	Aldedh domain-containing protein. (134 aa)
	A0A1L9VVH7	Aldedh domain-containing protein. (499 aa)
	A0A1L9VVW8	Uncharacterized protein. (308 aa)
	A0A1L9VVX3	Uncharacterized protein. (287 aa)
	A0A1L9VW81	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (462 aa)
	A0A1L9VWJ4	ADH_zinc_N domain-containing protein. (227 aa)
	A0A1L9VWJ8	Uncharacterized protein. (102 aa)
	A0A1L9VWS8	Uncharacterized protein. (73 aa)
	A0A1L9VXF6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (466 aa)
	A0A1L9VYD5	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	A0A1L9VYH1	Succinate-semialdehyde dehydrogenase. (532 aa)
	A0A1L9VZM2	Succinate-semialdehyde dehydrogenase. (532 aa)

Your Current Organism:

Aspergillus glaucus

NCBI taxonomy Id: 1160497
Other names: A. glaucus CBS 516.65, Aspergillus glaucus CBS 516.65

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1L9V3G2	A0A1L9V564	Uncharacterized protein.	Uncharacterized protein.	0.910
A0A1L9V3G2	A0A1L9V9G3	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.895
A0A1L9V3G2	A0A1L9VAZ0	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.894
A0A1L9V3G2	A0A1L9VES0	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.875
A0A1L9V3G2	A0A1L9VFH5	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L9V3G2	A0A1L9VFR5	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.958
A0A1L9V3G2	A0A1L9VG04	Uncharacterized protein.	Uncharacterized protein.	0.970
A0A1L9V3G2	A0A1L9VG50	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.838
A0A1L9V3G2	A0A1L9VJH3	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.777
A0A1L9V3G2	A0A1L9VJS2	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L9V3G2	A0A1L9VLD1	Uncharacterized protein.	AMP-binding domain-containing protein.	0.910
A0A1L9V3G2	A0A1L9VLV2	Uncharacterized protein.	Uncharacterized protein.	0.972
A0A1L9V3G2	A0A1L9VP00	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.980
A0A1L9V3G2	A0A1L9VRD2	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.838
A0A1L9V3G2	A0A1L9VXF6	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.424
A0A1L9V3T4	A0A1L9V4C2	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.478
A0A1L9V3T4	A0A1L9V5C6	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.478
A0A1L9V3T4	A0A1L9V5M0	Uncharacterized protein.	Uncharacterized protein.	0.478
A0A1L9V3T4	A0A1L9VI93	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.478
A0A1L9V3T4	A0A1L9VK66	Uncharacterized protein.	Aldedh domain-containing protein.	0.478