STRINGSTRING
SU9_02105 SU9_02105 SU9_02696 SU9_02696 SU9_04601 SU9_04601 SU9_04756 SU9_04756 arcA arcA dapF dapF dapA dapA dapB dapB SU9_06730 SU9_06730 SU9_06735 SU9_06735 lysA lysA SU9_08624 SU9_08624 SU9_08639 SU9_08639 SU9_09344 SU9_09344 SU9_10579 SU9_10579 proC proC SU9_12282 SU9_12282 asd asd SU9_13179 SU9_13179 lysA-2 lysA-2 SU9_15457 SU9_15457 SU9_16892 SU9_16892 SU9_18311 SU9_18311 SU9_20047 SU9_20047 asd-2 asd-2 proB proB proA proA SU9_21382 SU9_21382 SU9_22350 SU9_22350 dapD dapD dapA-2 dapA-2 argH argH argG argG argR argR argD argD argB argB argJ argJ argC argC SU9_31366 SU9_31366 SU9_31768 SU9_31768 SU9_32998 SU9_32998 SU9_33003 SU9_33003
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_02105COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
SU9_02696COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (301 aa)
SU9_04601Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase. (417 aa)
SU9_04756Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa)
arcACOG2235 Arginine deiminase. (411 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (291 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (250 aa)
SU9_06730COG1012 NAD-dependent aldehyde dehydrogenases. (546 aa)
SU9_06735COG0506 Proline dehydrogenase. (308 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
SU9_08624COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (363 aa)
SU9_08639COG0436 Aspartate/tyrosine/aromatic aminotransferase. (377 aa)
SU9_09344Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (403 aa)
SU9_10579COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa)
SU9_12282COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. (163 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (376 aa)
SU9_13179COG0527 Aspartokinases; Belongs to the aspartokinase family. (423 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (487 aa)
SU9_15457Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (392 aa)
SU9_16892Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (395 aa)
SU9_18311Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase. (444 aa)
SU9_20047COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (365 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa)
SU9_21382Amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (421 aa)
SU9_22350COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (321 aa)
dapDTransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (337 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (321 aa)
argHCOG0165 Argininosuccinate lyase. (480 aa)
argGCOG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (397 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (180 aa)
argDCOG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (309 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (383 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa)
SU9_31366COG0686 Alanine dehydrogenase. (371 aa)
SU9_31768COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. (329 aa)
SU9_32998COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. (272 aa)
SU9_33003Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (372 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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