STRINGSTRING
SU9_02519 SU9_02519 SU9_02891 SU9_02891 SU9_04876 SU9_04876 SU9_04896 SU9_04896 SU9_05266 SU9_05266 aroA aroA SU9_08252 SU9_08252 SU9_09459 SU9_09459 SU9_09904 SU9_09904 SU9_10973 SU9_10973 pat pat SU9_14256 SU9_14256 SU9_14486 SU9_14486 SU9_16207 SU9_16207 SU9_17420 SU9_17420 trpD trpD SU9_23025 SU9_23025 SU9_23030 SU9_23030 SU9_23345 SU9_23345 hisD hisD hisC hisC hisB hisB SU9_23375 SU9_23375 hisH hisH priA priA SU9_23390 SU9_23390 hisF hisF hisI hisI trpE trpE trpC trpC trpB trpB trpA trpA SU9_28461 SU9_28461 aroQ aroQ SU9_28876 SU9_28876 hisG hisG hisE hisE nusB nusB aroB aroB aroK aroK aroC aroC aroE aroE SU9_30061 SU9_30061 SU9_31081 SU9_31081 SU9_33693 SU9_33693 SU9_33753 SU9_33753
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SU9_02519COG1605 Chorismate mutase. (152 aa)
SU9_02891Putative inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (277 aa)
SU9_04876COG0512 Anthranilate/para-aminobenzoate synthases component II. (702 aa)
SU9_04896Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (389 aa)
SU9_05266Putative myo-inositol 1-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (281 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (454 aa)
SU9_08252COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (267 aa)
SU9_09459COG0337 3-dehydroquinate synthetase. (411 aa)
SU9_09904Monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (269 aa)
SU9_10973Hypothetical protein; COG1605 Chorismate mutase. (101 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
SU9_14256COG1260 Myo-inositol-1-phosphate synthase. (360 aa)
SU9_14486COG0512 Anthranilate/para-aminobenzoate synthases component II. (218 aa)
SU9_16207Hypothetical protein. (133 aa)
SU9_17420Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (437 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (354 aa)
SU9_23025COG0147 Anthranilate/para-aminobenzoate synthases component I. (656 aa)
SU9_23030Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (416 aa)
SU9_23345Transcriptional regulator; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (170 aa)
hisDBifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
hisCCOG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (376 aa)
hisBCOG0131 Imidazoleglycerol-phosphate dehydratase. (197 aa)
SU9_23375Hypothetical protein. (54 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
priAPhosphoribosyl isomerase A; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (240 aa)
SU9_23390Hypothetical protein; COG0251 Putative translation initiation inhibitor, yjgF family. (136 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (134 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (514 aa)
trpCCOG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (428 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa)
SU9_28461COG1605 Chorismate mutase. (210 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa)
SU9_28876Myo-inositol 1-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (272 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (282 aa)
hisECOG0140 Phosphoribosyl-ATP pyrophosphohydrolase. (90 aa)
nusBTranscription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (144 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (185 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
aroECOG0169 Shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (275 aa)
SU9_30061COG0147 Anthranilate/para-aminobenzoate synthases component I. (349 aa)
SU9_31081Putative inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (287 aa)
SU9_33693Aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (346 aa)
SU9_33753Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (396 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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