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xylA xylA xylB xylB SU9_01565 SU9_01565 SU9_01690 SU9_01690 SU9_02337 SU9_02337 SU9_03176 SU9_03176 SU9_03221 SU9_03221 SU9_05336 SU9_05336 pfkA pfkA SU9_07320 SU9_07320 nagB nagB SU9_09009 SU9_09009 glpX glpX SU9_09329 SU9_09329 SU9_09914 SU9_09914 SU9_11438 SU9_11438 SU9_11518 SU9_11518 SU9_11523 SU9_11523 SU9_11533 SU9_11533 gpmA gpmA SU9_15492 SU9_15492 glmM glmM glmS glmS SU9_17570 SU9_17570 SU9_17575 SU9_17575 SU9_17580 SU9_17580 SU9_17999 SU9_17999 glmU glmU eno eno SU9_18573 SU9_18573 SU9_19155 SU9_19155 SU9_19160 SU9_19160 SU9_19165 SU9_19165 SU9_19334 SU9_19334 SU9_19339 SU9_19339 glmS-2 glmS-2 SU9_20474 SU9_20474 SU9_20713 SU9_20713 SU9_21347 SU9_21347 SU9_21692 SU9_21692 SU9_21697 SU9_21697 SU9_21702 SU9_21702 SU9_22130 SU9_22130 SU9_22975 SU9_22975 pfp pfp SU9_23440 SU9_23440 SU9_23630 SU9_23630 SU9_23867 SU9_23867 SU9_23917 SU9_23917 pgk pgk tpiA tpiA pgi pgi tal tal SU9_23967 SU9_23967 xylB-2 xylB-2 SU9_25619 SU9_25619 SU9_25624 SU9_25624 SU9_27309 SU9_27309 SU9_27314 SU9_27314 SU9_28184 SU9_28184 SU9_28189 SU9_28189 SU9_28611 SU9_28611 SU9_28616 SU9_28616 SU9_28791 SU9_28791 SU9_29176 SU9_29176 SU9_29341 SU9_29341 SU9_29661 SU9_29661 SU9_30141 SU9_30141 SU9_30684 SU9_30684 SU9_32343 SU9_32343 pfkA-2 pfkA-2 SU9_33213 SU9_33213
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
xylACOG2115 Xylose isomerase; Belongs to the xylose isomerase family. (387 aa)
xylBXylulose kinase; COG1070 Sugar (pentulose and hexulose) kinases. (476 aa)
SU9_01565ROK family protein; COG1940 Transcriptional regulator/sugar kinase. (424 aa)
SU9_01690COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa)
SU9_02337COG0191 Fructose/tagatose bisphosphate aldolase. (293 aa)
SU9_03176ROK family glucokinase; COG1940 Transcriptional regulator/sugar kinase. (373 aa)
SU9_03221COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (222 aa)
SU9_05336Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. (93 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
SU9_07320COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
nagBCOG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase. (251 aa)
SU9_09009Polyphosphate glucokinase; COG1940 Transcriptional regulator/sugar kinase. (297 aa)
glpXCOG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. (343 aa)
SU9_09329COG0524 Sugar kinases, ribokinase family. (401 aa)
SU9_09914COG1349 Transcriptional regulators of sugar metabolism. (317 aa)
SU9_11438COG1264 Phosphotransferase system IIB components. (580 aa)
SU9_11518Sugar kinase; COG1940 Transcriptional regulator/sugar kinase. (308 aa)
SU9_11523COG1820 N-acetylglucosamine-6-phosphate deacetylase. (405 aa)
SU9_11533Sugar kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. (308 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
SU9_15492Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa)
SU9_17570COG1349 Transcriptional regulators of sugar metabolism. (260 aa)
SU9_175751-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. (315 aa)
SU9_17580PTS system fructose subfamily transporter subunit IIC; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (689 aa)
SU9_17999Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (264 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (485 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
SU9_18573PTS system mannose-specific transporter subunits IIBCA; COG1445 Phosphotransferase system fructose-specific component IIB. (722 aa)
SU9_19155PTS system transporter subunit IIC; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (423 aa)
SU9_19160PTS transmembrane protein; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (437 aa)
SU9_19165COG1264 Phosphotransferase system IIB components. (77 aa)
SU9_19334COG1940 Transcriptional regulator/sugar kinase. (74 aa)
SU9_19339COG1940 Transcriptional regulator/sugar kinase. (306 aa)
glmS-2Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
SU9_20474COG0698 Ribose 5-phosphate isomerase RpiB. (161 aa)
SU9_20713Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. (214 aa)
SU9_21347Carbohydrate kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family. (487 aa)
SU9_21692COG0524 Sugar kinases, ribokinase family. (340 aa)
SU9_216972-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (206 aa)
SU9_21702Galactonate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily. (381 aa)
SU9_221302-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (214 aa)
SU9_22975Glucokinase; COG1940 Transcriptional regulator/sugar kinase. (313 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
SU9_23440Hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (221 aa)
SU9_23630COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
SU9_23867PfkB domain-containing protein; COG0524 Sugar kinases, ribokinase family. (333 aa)
SU9_23917COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgiCOG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. (550 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (380 aa)
SU9_23967Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (699 aa)
xylB-2D-xylulose kinase; COG1070 Sugar (pentulose and hexulose) kinases. (467 aa)
SU9_25619Zinc-containing alcohol dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (332 aa)
SU9_25624COG1349 Transcriptional regulators of sugar metabolism. (246 aa)
SU9_27309Hypothetical protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (346 aa)
SU9_27314COG1349 Transcriptional regulators of sugar metabolism. (262 aa)
SU9_28184Phosphoenolpyruvate-dependent sugar phosphotransferase; COG2190 Phosphotransferase system IIA components. (149 aa)
SU9_28189Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)
SU9_28611COG3957 Phosphoketolase. (695 aa)
SU9_28616COG3957 Phosphoketolase. (104 aa)
SU9_28791COG1349 Transcriptional regulators of sugar metabolism. (253 aa)
SU9_29176COG1940 Transcriptional regulator/sugar kinase. (318 aa)
SU9_29341COG1940 Transcriptional regulator/sugar kinase. (352 aa)
SU9_29661COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
SU9_30141COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (180 aa)
SU9_30684Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (263 aa)
SU9_32343COG1349 Transcriptional regulators of sugar metabolism. (270 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
SU9_33213Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (259 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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