STRINGSTRING
SU9_01080 SU9_01080 fdhD fdhD rsgA rsgA SU9_06115 SU9_06115 SU9_06480 SU9_06480 thiL thiL rsgA-2 rsgA-2 SU9_08299 SU9_08299 SU9_08339 SU9_08339 SU9_08414 SU9_08414 SU9_11343 SU9_11343 mqnD mqnD SU9_14061 SU9_14061 SU9_14066 SU9_14066 SU9_14651 SU9_14651 SU9_14656 SU9_14656 SU9_16212 SU9_16212 ubiA ubiA ubiX ubiX SU9_16237 SU9_16237 SU9_16242 SU9_16242 mqnE mqnE SU9_16252 SU9_16252 SU9_16257 SU9_16257 SU9_16297 SU9_16297 mqnA mqnA mqnC mqnC SU9_16317 SU9_16317 ubiE ubiE SU9_16327 SU9_16327 SU9_17485 SU9_17485 SU9_17717 SU9_17717 SU9_17727 SU9_17727 moaC moaC SU9_17737 SU9_17737 SU9_17742 SU9_17742 SU9_17752 SU9_17752 SU9_19140 SU9_19140 SU9_22465 SU9_22465 thiG thiG SU9_23065 SU9_23065 SU9_23070 SU9_23070 SU9_23080 SU9_23080 thiE thiE SU9_23095 SU9_23095 SU9_23350 SU9_23350 SU9_23675 SU9_23675 moaA moaA SU9_25134 SU9_25134 SU9_25139 SU9_25139 SU9_25144 SU9_25144 SU9_25149 SU9_25149 SU9_28921 SU9_28921 thiG-2 thiG-2 SU9_30609 SU9_30609 mqnD-2 mqnD-2 mqnE-2 mqnE-2 SU9_33383 SU9_33383 mqnC-2 mqnC-2 mqnA-2 mqnA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_01080Hypothetical protein. (113 aa)
fdhDFormate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (288 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (391 aa)
SU9_06115COG1816 Adenosine deaminase. (340 aa)
SU9_06480COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (269 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (325 aa)
rsgA-2Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (335 aa)
SU9_08299moaE-like protein; COG0314 Molybdopterin converting factor, large subunit. (159 aa)
SU9_08339UBA/THIF-type NAD/FAD binding protein. (375 aa)
SU9_08414Molybdopterin biosynthesis-like protein MoeZ; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (392 aa)
SU9_11343Hypothetical protein; COG0775 Nucleoside phosphorylase. (208 aa)
mqnDHypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (283 aa)
SU9_14061Phosphomethylpyrimidine synthase ThiC; COG0422 Thiamine biosynthesis protein ThiC. (294 aa)
SU9_14066Phosphomethylpyrimidine synthase ThiC; COG0422 Thiamine biosynthesis protein ThiC. (301 aa)
SU9_14651Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (306 aa)
SU9_14656Molybdenum cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (565 aa)
SU9_16212Decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (484 aa)
ubiAPrenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. (300 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (240 aa)
SU9_16237Hypothetical protein. (44 aa)
SU9_16242Transcriptional regulator, AsnC family protein; COG1522 Transcriptional regulators. (152 aa)
mqnEHypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
SU9_16252COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (174 aa)
SU9_16257Hypothetical protein. (96 aa)
SU9_16297COG1278 Cold shock proteins. (67 aa)
mqnAHypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (276 aa)
mqnCHypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (399 aa)
SU9_16317Hypothetical protein. (196 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (233 aa)
SU9_16327Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). (437 aa)
SU9_17485Hypothetical protein. (203 aa)
SU9_17717Ligase; COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (186 aa)
SU9_17727Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (438 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa)
SU9_17737COG0521 Molybdopterin biosynthesis enzymes. (167 aa)
SU9_17742GCN5-like N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (204 aa)
SU9_17752Putative AsnC family transcriptional regulator. (103 aa)
SU9_19140Hypothetical protein; COG1977 Molybdopterin converting factor, small subunit. (92 aa)
SU9_22465Hypothetical protein. (243 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (279 aa)
SU9_23065COG2104 Sulfur transfer protein involved in thiamine biosynthesis. (71 aa)
SU9_23070COG0665 Glycine/D-amino acid oxidases (deaminating). (391 aa)
SU9_23080Transcriptional regulatory protein. (121 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (216 aa)
SU9_23095Hypothetical protein. (407 aa)
SU9_23350COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease. (248 aa)
SU9_23675COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)
SU9_25134COG2005 N-terminal domain of molybdenum-binding protein. (139 aa)
SU9_25139TOBE domain-containing protein; COG2452 Predicted site-specific integrase-resolvase. (131 aa)
SU9_25144Molybdenum ABC transporter periplasmic molybdate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component. (266 aa)
SU9_25149ABC transporter ATPase/permease; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the binding-protein-dependent transport system permease family. (657 aa)
SU9_28921Hypothetical protein; COG1977 Molybdopterin converting factor, small subunit. (92 aa)
thiG-2Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
SU9_30609COG1141 Ferredoxin. (97 aa)
mqnD-2Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (291 aa)
mqnE-2Hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
SU9_33383COG1141 Ferredoxin. (101 aa)
mqnC-2Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (422 aa)
mqnA-2Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (301 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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