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| | SU9_01135 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. (389 aa) |
| | gabD1 | Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases. (465 aa) |
| | SU9_02494 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (507 aa) |
| | SU9_02504 | GMC family oxidoreductase; COG2303 Choline dehydrogenase and related flavoproteins. (514 aa) |
| | SU9_02856 | COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (374 aa) |
| | SU9_02906 | COG0095 Lipoate-protein ligase A. (355 aa) |
| | SU9_02961 | Class III aminotransferase; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa) |
| | SU9_03141 | COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (490 aa) |
| | SU9_03281 | COG2225 Malate synthase; Belongs to the malate synthase family. (542 aa) |
| | SU9_03541 | Pyruvate dehydrogenase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (580 aa) |
| | SU9_03546 | Hypothetical protein. (376 aa) |
| | SU9_04061 | COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (289 aa) |
| | SU9_04346 | Flavoprotein oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (460 aa) |
| | SU9_04446 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa) |
| | SU9_05021 | COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (632 aa) |
| | SU9_05136 | Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (593 aa) |
| | SU9_05371 | COG0372 Citrate synthase; Belongs to the citrate synthase family. (389 aa) |
| | SU9_05376 | Citrate synthase-like protein; COG0372 Citrate synthase. (415 aa) |
| | SU9_06055 | COG1012 NAD-dependent aldehyde dehydrogenases. (486 aa) |
| | SU9_06070 | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa) |
| | SU9_06105 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (505 aa) |
| | SU9_06125 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (484 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa) |
| | SU9_06665 | Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (544 aa) |
| | SU9_06705 | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (368 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (346 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | ilvH | COG0440 Acetolactate synthase, small (regulatory) subunit. (174 aa) |
| | SU9_06775 | Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (622 aa) |
| | SU9_06935 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (458 aa) |
| | SU9_07310 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa) |
| | ackA | Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (406 aa) |
| | kgd | Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1270 aa) |
| | SU9_07960 | Malate oxidoreductase; COG0281 Malic enzyme. (407 aa) |
| | SU9_09059 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (557 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (473 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa) |
| | SU9_09919 | Flavoprotein disulfide reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (481 aa) |
| | SU9_09944 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (333 aa) |
| | SU9_09949 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa) |
| | SU9_09954 | COG1012 NAD-dependent aldehyde dehydrogenases. (280 aa) |
| | SU9_10249 | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (126 aa) |
| | SU9_10254 | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. (162 aa) |
| | sdhA-2 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (584 aa) |
| | sdhB | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (257 aa) |
| | SU9_10708 | GMC family oxidoreductase; COG2303 Choline dehydrogenase and related flavoproteins. (514 aa) |
| | SU9_10713 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (489 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa) |
| | gabD2 | Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (578 aa) |
| | SU9_11103 | COG0372 Citrate synthase; Belongs to the citrate synthase family. (367 aa) |
| | SU9_11208 | FAD linked oxidase domain-containing protein; COG0277 FAD/FMN-containing dehydrogenases. (981 aa) |
| | ilvD | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (616 aa) |
| | SU9_12502 | COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (471 aa) |
| | SU9_12517 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (485 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | SU9_14636 | COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (397 aa) |
| | SU9_14641 | Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (344 aa) |
| | SU9_14646 | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (521 aa) |
| | SU9_14706 | COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (404 aa) |
| | SU9_14711 | Transketolase central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (327 aa) |
| | SU9_14716 | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (490 aa) |
| | SU9_15572 | Hypothetical protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | SU9_15654 | Valine dehydrogenase (NADP+); COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (373 aa) |
| | SU9_16457 | COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (364 aa) |
| | SU9_16462 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (650 aa) |
| | SU9_17002 | Inosine 5-monophosphate dehydrogenase; COG0516 IMP dehydrogenase/GMP reductase. (371 aa) |
| | SU9_17110 | Hypothetical protein; COG1042 Acyl-CoA synthetase (NDP forming). (751 aa) |
| | SU9_17345 | COG2513 PEP phosphonomutase and related enzymes. (276 aa) |
| | SU9_17665 | COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (140 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (921 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (324 aa) |
| | SU9_18920 | NAD-binding malic protein; COG0281 Malic enzyme. (477 aa) |
| | SU9_19075 | Putative oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (481 aa) |
| | gltA | COG0372 Citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | SU9_19877 | COG1012 NAD-dependent aldehyde dehydrogenases. (497 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (592 aa) |
| | SU9_21098 | Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (893 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (910 aa) |
| | SU9_22000 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa) |
| | SU9_22620 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (671 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (316 aa) |
| | lipB | Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (257 aa) |
| | SU9_22710 | 2-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa) |
| | SU9_22725 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (462 aa) |
| | SU9_23020 | COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa) |
| | SU9_23520 | COG0067 Glutamate synthase domain 1. (1513 aa) |
| | gltD | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (486 aa) |
| | SU9_24122 | COG1012 NAD-dependent aldehyde dehydrogenases. (492 aa) |
| | SU9_25554 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COG0388 Predicted amidohydrolase. (264 aa) |
| | gltD-2 | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (501 aa) |
| | SU9_26884 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1124 aa) |
| | SU9_28119 | Putative transposase for IS112. (163 aa) |
| | SU9_29301 | COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa) |
| | SU9_30056 | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (274 aa) |
| | SU9_31688 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (509 aa) |
| | SU9_31718 | COG0277 FAD/FMN-containing dehydrogenases. (984 aa) |
| | SU9_31723 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (382 aa) |
| | SU9_32928 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (460 aa) |
| | SU9_33023 | COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (864 aa) |
