STRINGSTRING
SU9_02000 SU9_02000 SU9_02731 SU9_02731 SU9_02736 SU9_02736 SU9_03436 SU9_03436 SU9_03676 SU9_03676 SU9_03981 SU9_03981 SU9_03986 SU9_03986 SU9_04016 SU9_04016 SU9_04026 SU9_04026 SU9_04996 SU9_04996 SU9_05596 SU9_05596 SU9_05726 SU9_05726 ispG ispG SU9_06940 SU9_06940 SU9_07720 SU9_07720 SU9_10569 SU9_10569 SU9_10913 SU9_10913 SU9_13414 SU9_13414 SU9_13419 SU9_13419 SU9_13645 SU9_13645 SU9_13780 SU9_13780 SU9_15127 SU9_15127 mqnE mqnE bioB bioB SU9_00335 SU9_00335 SU9_00340 SU9_00340 SU9_00825 SU9_00825 SU9_00895 SU9_00895 SU9_00910 SU9_00910 SU9_01175 SU9_01175 egtB egtB SU9_01750 SU9_01750 SU9_01755 SU9_01755 SU9_01970 SU9_01970 mqnC mqnC nuoB nuoB nuoI nuoI nuoB-2 nuoB-2 nuoI-2 nuoI-2 tsaD tsaD SU9_17390 SU9_17390 SU9_17500 SU9_17500 SU9_18131 SU9_18131 hutI hutI SU9_18518 SU9_18518 SU9_18965 SU9_18965 SU9_20953 SU9_20953 SU9_20958 SU9_20958 SU9_21960 SU9_21960 SU9_22005 SU9_22005 SU9_22625 SU9_22625 SU9_22880 SU9_22880 SU9_23040 SU9_23040 SU9_24037 SU9_24037 SU9_24152 SU9_24152 SU9_24392 SU9_24392 SU9_25404 SU9_25404 SU9_25439 SU9_25439 SU9_25444 SU9_25444 SU9_25534 SU9_25534 SU9_26054 SU9_26054 SU9_26139 SU9_26139 SU9_26349 SU9_26349 SU9_26384 SU9_26384 SU9_26709 SU9_26709 SU9_26839 SU9_26839 SU9_27419 SU9_27419 SU9_27429 SU9_27429 SU9_27489 SU9_27489 SU9_27679 SU9_27679 SU9_27704 SU9_27704 SU9_28681 SU9_28681 SU9_28961 SU9_28961 SU9_29671 SU9_29671 SU9_30609 SU9_30609 hmgA hmgA SU9_31101 SU9_31101 SU9_31808 SU9_31808 SU9_31883 SU9_31883 SU9_32128 SU9_32128 SU9_32238 SU9_32238 SU9_32453 SU9_32453 SU9_32498 SU9_32498 SU9_33358 SU9_33358 mqnE-2 mqnE-2 SU9_33383 SU9_33383 mqnC-2 mqnC-2 SU9_33438 SU9_33438 SU9_33488 SU9_33488 SU9_33593 SU9_33593 SU9_33598 SU9_33598 SU9_33713 SU9_33713 SU9_33723 SU9_33723 SU9_33748 SU9_33748
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_02000Hypothetical protein; COG0823 Periplasmic component of the Tol biopolymer transport system. (1066 aa)
SU9_02731COG2124 Cytochrome P450. (395 aa)
SU9_02736COG1141 Ferredoxin. (63 aa)
SU9_03436Xanthine dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (795 aa)
SU9_03676Aldehyde oxidase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (721 aa)
SU9_03981COG2124 Cytochrome P450. (402 aa)
SU9_03986COG1141 Ferredoxin. (65 aa)
SU9_04016COG2124 Cytochrome P450. (396 aa)
SU9_04026COG2124 Cytochrome P450. (424 aa)
SU9_04996Hypothetical protein. (300 aa)
SU9_05596Hypothetical protein. (236 aa)
SU9_05726COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (156 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (385 aa)
SU9_06940Hypothetical protein. (230 aa)
SU9_07720COG2124 Cytochrome P450. (363 aa)
SU9_10569COG2124 Cytochrome P450. (425 aa)
SU9_10913Hypothetical protein; COG0627 Predicted esterase. (374 aa)
SU9_13414COG2124 Cytochrome P450. (412 aa)
SU9_13419COG1141 Ferredoxin. (66 aa)
SU9_13645Extradiol ring-cleavage dioxygenase class III protein subunit B. (293 aa)
SU9_13780COG2124 Cytochrome P450. (396 aa)
SU9_15127COG2124 Cytochrome P450. (417 aa)
mqnEHypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (391 aa)
SU9_00335COG2124 Cytochrome P450. (302 aa)
SU9_00340COG2124 Cytochrome P450. (432 aa)
SU9_00825COG2124 Cytochrome P450. (399 aa)
SU9_00895COG2124 Cytochrome P450. (400 aa)
SU9_00910COG2124 Cytochrome P450. (412 aa)
SU9_01175Oxidoreductase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (714 aa)
egtBHypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (439 aa)
SU9_01750Bifunctional P-450:NADPH-P450 reductase 1; COG0369 Sulfite reductase, alpha subunit (flavoprotein). (476 aa)
SU9_01755Bifunctional P-450:NADPH-P450 reductase 1; COG2124 Cytochrome P450. (518 aa)
SU9_01970COG2124 Cytochrome P450. (417 aa)
mqnCHypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (399 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoINADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (194 aa)
nuoB-2NADH dehydrogenase subunit NuoB2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (214 aa)
nuoI-2NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (196 aa)
tsaDUGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (375 aa)
SU9_17390Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (220 aa)
SU9_17500Cytochrome P450-like enzyme; COG2124 Cytochrome P450. (396 aa)
SU9_18131Monooxygenase; COG2124 Cytochrome P450. (456 aa)
hutICOG1228 Imidazolonepropionase and related amidohydrolases. (393 aa)
SU9_18518Cysteine dioxygenase type I; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (165 aa)
SU9_18965Aldehyde oxidase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (776 aa)
SU9_20953COG2124 Cytochrome P450. (411 aa)
SU9_20958Hypothetical protein; COG2124 Cytochrome P450. (460 aa)
SU9_21960COG2124 Cytochrome P450. (410 aa)
SU9_22005Iron-sulfur protein; COG1141 Ferredoxin. (77 aa)
SU9_22625Hypothetical protein. (289 aa)
SU9_22880COG2010 Cytochrome c, mono- and diheme variants. (269 aa)
SU9_23040Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (158 aa)
SU9_24037SUF system FeS assembly protein, NifU family; COG0822 NifU homolog involved in Fe-S cluster formation. (152 aa)
SU9_24152Ectoine hydroxylase. (299 aa)
SU9_24392Hypothetical protein; COG3000 Sterol desaturase. (303 aa)
SU9_25404COG2124 Cytochrome P450. (423 aa)
SU9_25439Hypothetical protein; COG1141 Ferredoxin. (71 aa)
SU9_25444Cytochrome P450-like enzyme; COG2124 Cytochrome P450. (396 aa)
SU9_25534Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. (388 aa)
SU9_26054COG2124 Cytochrome P450. (401 aa)
SU9_26139phytanoyl-CoA dioxygenase. (303 aa)
SU9_26349COG2124 Cytochrome P450. (402 aa)
SU9_26384COG2124 Cytochrome P450. (371 aa)
SU9_26709COG2124 Cytochrome P450. (403 aa)
SU9_26839Aldehyde oxidase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (730 aa)
SU9_27419COG1141 Ferredoxin. (81 aa)
SU9_27429COG2124 Cytochrome P450. (405 aa)
SU9_27489COG2124 Cytochrome P450. (431 aa)
SU9_27679SUF system FeS assembly protein, NifU family; COG0822 NifU homolog involved in Fe-S cluster formation. (145 aa)
SU9_27704Ferritin Dps family protein; COG2193 Bacterioferritin (cytochrome b1). (181 aa)
SU9_28681Ferritin; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (198 aa)
SU9_28961Phytanoyl-CoA dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin. (266 aa)
SU9_29671Intradiol ring-cleavage dioxygenase; COG3485 Protocatechuate 3,4-dioxygenase beta subunit. (253 aa)
SU9_30609COG1141 Ferredoxin. (97 aa)
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (441 aa)
SU9_31101Bifunctional: xanthine dehydrogenase/ 4-hydroxybenzoyl-CoA reductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. (905 aa)
SU9_31808Molybdopterin binding aldehyde oxidase and xanthine dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. (749 aa)
SU9_31883Methylesterase; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. (335 aa)
SU9_32128COG2124 Cytochrome P450. (411 aa)
SU9_32238Rieske (2Fe-2S) domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. (383 aa)
SU9_32453[NiFe] hydrogenase expression/formation protein; COG0298 Hydrogenase maturation factor. (116 aa)
SU9_32498Hypothetical protein. (202 aa)
SU9_33358COG2124 Cytochrome P450. (405 aa)
mqnE-2Hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
SU9_33383COG1141 Ferredoxin. (101 aa)
mqnC-2Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (422 aa)
SU9_33438Hypothetical protein. (246 aa)
SU9_33488COG2124 Cytochrome P450. (464 aa)
SU9_33593COG2124 Cytochrome P450. (379 aa)
SU9_33598COG1141 Ferredoxin. (67 aa)
SU9_33713COG2124 Cytochrome P450. (403 aa)
SU9_33723COG1141 Ferredoxin. (76 aa)
SU9_33748COG2124 Cytochrome P450. (399 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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