STRINGSTRING
SU9_02130 SU9_02130 SU9_02140 SU9_02140 SU9_02145 SU9_02145 SU9_03041 SU9_03041 SU9_04631 SU9_04631 SU9_04896 SU9_04896 miaA miaA SU9_07555 SU9_07555 SU9_07855 SU9_07855 aroA aroA SU9_08614 SU9_08614 SU9_09174 SU9_09174 SU9_09604 SU9_09604 SU9_12387 SU9_12387 SU9_14106 SU9_14106 SU9_14141 SU9_14141 SU9_14436 SU9_14436 SU9_15212 SU9_15212 speE speE hemC hemC ubiA ubiA ubiX ubiX mqnE mqnE mqnC mqnC fbiC fbiC SU9_17420 SU9_17420 murA murA SU9_21003 SU9_21003 nadA nadA SU9_23030 SU9_23030 thiE thiE trpA trpA ctaB ctaB SU9_24232 SU9_24232 SU9_25459 SU9_25459 SU9_25474 SU9_25474 hemC-2 hemC-2 SU9_27449 SU9_27449 SU9_28064 SU9_28064 ribH ribH SU9_29576 SU9_29576 metK metK SU9_31888 SU9_31888 mqnE-2 mqnE-2 mqnC-2 mqnC-2 SU9_33753 SU9_33753
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SU9_02130Polyprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (354 aa)
SU9_02140COG1562 Phytoene/squalene synthetase. (313 aa)
SU9_02145Squalene synthase HpnC; COG1562 Phytoene/squalene synthetase. (288 aa)
SU9_03041Hypothetical protein; COG0435 Predicted glutathione S-transferase. (356 aa)
SU9_04631COG0192 S-adenosylmethionine synthetase. (144 aa)
SU9_04896Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (389 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (312 aa)
SU9_07555Hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
SU9_07855Hypothetical protein; COG0421 Spermidine synthase. (224 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (454 aa)
SU9_08614Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (299 aa)
SU9_09174Putative undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)
SU9_09604COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (357 aa)
SU9_12387Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (294 aa)
SU9_14106COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (375 aa)
SU9_14141COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol. (148 aa)
SU9_14436COG0031 Cysteine synthase. (323 aa)
SU9_15212Hypothetical protein; COG1562 Phytoene/squalene synthetase. (308 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (574 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (338 aa)
ubiAPrenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. (300 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (240 aa)
mqnEHypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
mqnCHypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (399 aa)
fbiCFO synthase; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (848 aa)
SU9_17420Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (437 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (449 aa)
SU9_21003UDP phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (272 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (396 aa)
SU9_23030Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (416 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (216 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (285 aa)
SU9_24232cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; COG2109 ATP:corrinoid adenosyltransferase. (198 aa)
SU9_25459COG0031 Cysteine synthase. (312 aa)
SU9_25474Cys; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (400 aa)
hemC-2Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
SU9_27449COG0031 Cysteine synthase. (395 aa)
SU9_28064COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (453 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (161 aa)
SU9_29576COG0307 Riboflavin synthase alpha chain. (214 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
SU9_31888COG1562 Phytoene/squalene synthetase. (331 aa)
mqnE-2Hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
mqnC-2Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (422 aa)
SU9_33753Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (396 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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