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SU9_01040 SU9_01040 SU9_01245 SU9_01245 SU9_04566 SU9_04566 SU9_05511 SU9_05511 gpsA gpsA SU9_06785 SU9_06785 gcvH gcvH SU9_07775 SU9_07775 kgd kgd SU9_08165 SU9_08165 SU9_08170 SU9_08170 SU9_08474 SU9_08474 SU9_08944 SU9_08944 SU9_10249 SU9_10249 SU9_12147 SU9_12147 nuoD nuoD SU9_12372 SU9_12372 SU9_14576 SU9_14576 SU9_14586 SU9_14586 SU9_14591 SU9_14591 paaA paaA SU9_14646 SU9_14646 SU9_14716 SU9_14716 SU9_15562 SU9_15562 SU9_16307 SU9_16307 nuoB nuoB nuoC nuoC nuoD-2 nuoD-2 SU9_16367 SU9_16367 SU9_16372 SU9_16372 SU9_16377 SU9_16377 nuoI nuoI SU9_16407 SU9_16407 nuoB-2 nuoB-2 SU9_16502 SU9_16502 nuoI-2 nuoI-2 guaB guaB SU9_17002 SU9_17002 SU9_17020 SU9_17020 SU9_17025 SU9_17025 SU9_17170 SU9_17170 SU9_18805 SU9_18805 SU9_18810 SU9_18810 SU9_19060 SU9_19060 SU9_19280 SU9_19280 SU9_19459 SU9_19459 aceE aceE SU9_21752 SU9_21752 SU9_22175 SU9_22175 SU9_22295 SU9_22295 SU9_22305 SU9_22305 SU9_22710 SU9_22710 SU9_22725 SU9_22725 gltD gltD SU9_23675 SU9_23675 gcvP gcvP SU9_26059 SU9_26059 gltD-2 gltD-2 SU9_28601 SU9_28601 SU9_30081 SU9_30081 SU9_30674 SU9_30674 SU9_30859 SU9_30859 SU9_32228 SU9_32228 SU9_32508 SU9_32508
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SU9_01040NADPH-ferredoxin reductase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (452 aa)
SU9_01245NADH-ubiquinone/plastoquinone (complex I) oxidoreductase; COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit. (610 aa)
SU9_04566Hypothetical protein. (289 aa)
SU9_05511Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (958 aa)
gpsACOG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa)
SU9_06785NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (325 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
SU9_07775Hypothetical protein. (308 aa)
kgdAlpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1270 aa)
SU9_08165Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (800 aa)
SU9_08170Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (381 aa)
SU9_08474Hypothetical protein. (248 aa)
SU9_08944COG0515 Serine/threonine protein kinase. (456 aa)
SU9_10249COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (126 aa)
SU9_12147COG0515 Serine/threonine protein kinase. (798 aa)
nuoDNADH dehydrogenase I subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (380 aa)
SU9_123722-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (207 aa)
SU9_14576Phenylacetic acid degradation NADH oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (347 aa)
SU9_14586Putative phenylacetic acid degradation protein; COG3396 Uncharacterized conserved protein; overlaps another CDS with the same product name. (238 aa)
SU9_14591phenylacetate-CoA oxygenase subunit PaaH; COG3460 Uncharacterized enzyme of phenylacetate metabolism. (112 aa)
paaAphenylacetate-CoA oxygenase subunit PaaA. (316 aa)
SU9_14646Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (521 aa)
SU9_14716Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (490 aa)
SU9_15562COG0515 Serine/threonine protein kinase. (560 aa)
SU9_16307COG0515 Serine/threonine protein kinase. (627 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoCNADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (254 aa)
nuoD-2NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (458 aa)
SU9_16367COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. (294 aa)
SU9_16372NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (460 aa)
SU9_16377NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (853 aa)
nuoINADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (194 aa)
SU9_16407COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M). (552 aa)
nuoB-2NADH dehydrogenase subunit NuoB2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (214 aa)
SU9_16502NADH dehydrogenase (ubiquinone) 30 kDa subunit; COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit. (373 aa)
nuoI-2NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (196 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
SU9_17002Inosine 5-monophosphate dehydrogenase; COG0516 IMP dehydrogenase/GMP reductase. (371 aa)
SU9_17020COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (103 aa)
SU9_17025COG0578 Glycerol-3-phosphate dehydrogenase. (451 aa)
SU9_17170COG0515 Serine/threonine protein kinase. (324 aa)
SU9_18805COG0515 Serine/threonine protein kinase. (542 aa)
SU9_18810COG0515 Serine/threonine protein kinase. (423 aa)
SU9_19060Putative oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. (454 aa)
SU9_19280Oxidoreductase; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. (515 aa)
SU9_19459NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (910 aa)
SU9_21752COG0515 Serine/threonine protein kinase. (466 aa)
SU9_22175Hypothetical protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (815 aa)
SU9_22295Hypothetical protein; COG0672 High-affinity Fe2+/Pb2+ permease. (330 aa)
SU9_22305Peptidase M75, Imelysin; COG2822 Predicted periplasmic lipoprotein involved in iron transport. (384 aa)
SU9_227102-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
SU9_22725COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (462 aa)
gltDCOG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (486 aa)
SU9_23675COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
SU9_26059Peptidase M75, Imelysin; COG2822 Predicted periplasmic lipoprotein involved in iron transport. (391 aa)
gltD-2COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (501 aa)
SU9_28601Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (1402 aa)
SU9_30081COG0515 Serine/threonine protein kinase. (444 aa)
SU9_30674COG0578 Glycerol-3-phosphate dehydrogenase. (534 aa)
SU9_30859Hypothetical protein; COG2864 Cytochrome b subunit of formate dehydrogenase. (234 aa)
SU9_32228Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. (428 aa)
SU9_32508COG1740 Ni,Fe-hydrogenase I small subunit. (362 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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