(13 nodes) Translation protein, beta-barrel domain superfamily network (Streptomyces auratus)

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	lepA	GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (624 aa)
	SU9_29966	COG0480 Translation elongation factors (GTPases). (705 aa)
	tuf	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (390 aa)
	SU9_03831	Sulfate adenylyltransferase large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (450 aa)
	SU9_04191	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases). (604 aa)
	infB	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (613 aa)
	rimM	16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (176 aa)
	SU9_08784	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response. (634 aa)
	SU9_14441	tRNA synthetase-related protein; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain. (245 aa)
	fusA	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (706 aa)
	tuf-2	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa)
	rplC	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (214 aa)
	alaS	alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (889 aa)

Your Current Organism:

Streptomyces auratus

NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SU9_04191	SU9_08784	SU9_04191	SU9_08784	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	0.519
SU9_04191	infB	SU9_04191	SU9_05985	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.726
SU9_04191	rimM	SU9_04191	SU9_06320	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.	0.802
SU9_04191	rplC	SU9_04191	SU9_16672	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.991
SU9_04191	tuf	SU9_04191	SU9_00405	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.948
SU9_04191	tuf-2	SU9_04191	SU9_16662	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.940
SU9_08784	SU9_04191	SU9_08784	SU9_04191	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	Small GTP-binding protein; COG0480 Translation elongation factors (GTPases).	0.519
SU9_08784	SU9_29966	SU9_08784	SU9_29966	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	COG0480 Translation elongation factors (GTPases).	0.519
SU9_08784	fusA	SU9_08784	SU9_16657	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.519
SU9_08784	lepA	SU9_08784	SU9_20788	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.451
SU9_08784	rplC	SU9_08784	SU9_16672	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.565
SU9_14441	alaS	SU9_14441	SU9_29831	tRNA synthetase-related protein; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.	alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	0.716
SU9_29966	SU9_08784	SU9_29966	SU9_08784	COG0480 Translation elongation factors (GTPases).	GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.	0.519
SU9_29966	infB	SU9_29966	SU9_05985	COG0480 Translation elongation factors (GTPases).	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.792
SU9_29966	lepA	SU9_29966	SU9_20788	COG0480 Translation elongation factors (GTPases).	GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.531
SU9_29966	rimM	SU9_29966	SU9_06320	COG0480 Translation elongation factors (GTPases).	16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.	0.802
SU9_29966	rplC	SU9_29966	SU9_16672	COG0480 Translation elongation factors (GTPases).	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.993
SU9_29966	tuf	SU9_29966	SU9_00405	COG0480 Translation elongation factors (GTPases).	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.979
SU9_29966	tuf-2	SU9_29966	SU9_16662	COG0480 Translation elongation factors (GTPases).	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.979
alaS	SU9_14441	SU9_29831	SU9_14441	alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	tRNA synthetase-related protein; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.	0.716