STRINGSTRING
SU9_02571 SU9_02571 SU9_00215 SU9_00215 SU9_00950 SU9_00950 SU9_01690 SU9_01690 SU9_01785 SU9_01785 SU9_02337 SU9_02337 SU9_14716 SU9_14716 SU9_15482 SU9_15482 SU9_15492 SU9_15492 SU9_15664 SU9_15664 SU9_16457 SU9_16457 SU9_16462 SU9_16462 SU9_17085 SU9_17085 SU9_17110 SU9_17110 SU9_17665 SU9_17665 eno eno SU9_18301 SU9_18301 SU9_18558 SU9_18558 SU9_19075 SU9_19075 SU9_19334 SU9_19334 SU9_19339 SU9_19339 SU9_19862 SU9_19862 SU9_20349 SU9_20349 SU9_20354 SU9_20354 SU9_20713 SU9_20713 SU9_20863 SU9_20863 SU9_20873 SU9_20873 SU9_21098 SU9_21098 SU9_21507 SU9_21507 aceE aceE SU9_22000 SU9_22000 SU9_22095 SU9_22095 SU9_22710 SU9_22710 SU9_22725 SU9_22725 SU9_22975 SU9_22975 pfp pfp SU9_23440 SU9_23440 SU9_23630 SU9_23630 SU9_23695 SU9_23695 SU9_23917 SU9_23917 pgk pgk tpiA tpiA pgi pgi SU9_25524 SU9_25524 SU9_25919 SU9_25919 SU9_27554 SU9_27554 SU9_28184 SU9_28184 SU9_28289 SU9_28289 SU9_29131 SU9_29131 SU9_29176 SU9_29176 SU9_29341 SU9_29341 SU9_30754 SU9_30754 SU9_31001 SU9_31001 SU9_31006 SU9_31006 SU9_31688 SU9_31688 SU9_32068 SU9_32068 pfkA-2 pfkA-2 SU9_03176 SU9_03176 SU9_04421 SU9_04421 SU9_04441 SU9_04441 SU9_05331 SU9_05331 SU9_05491 SU9_05491 SU9_06055 SU9_06055 pfkA pfkA SU9_07320 SU9_07320 SU9_09009 SU9_09009 glpX glpX pckG pckG SU9_09444 SU9_09444 SU9_09949 SU9_09949 SU9_11518 SU9_11518 gpmA gpmA acsA acsA SU9_13439 SU9_13439 SU9_14636 SU9_14636 SU9_14641 SU9_14641 SU9_14646 SU9_14646 SU9_14706 SU9_14706 SU9_14711 SU9_14711
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_02571Putative oxidoreductase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (277 aa)
SU9_00215COG1940 Transcriptional regulator/sugar kinase. (385 aa)
SU9_00950COG3564 Uncharacterized protein conserved in bacteria. (141 aa)
SU9_01690COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa)
SU9_01785Hypothetical protein; COG3537 Putative alpha-1,2-mannosidase. (794 aa)
SU9_02337COG0191 Fructose/tagatose bisphosphate aldolase. (293 aa)
SU9_14716Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (490 aa)
SU9_15482Aldose 1-epimerase; COG2017 Galactose mutarotase and related enzymes. (297 aa)
SU9_15492Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
SU9_15664DNA-binding protein; COG2452 Predicted site-specific integrase-resolvase. (68 aa)
SU9_16457COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (364 aa)
SU9_16462Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (650 aa)
SU9_17085COG1062 Zn-dependent alcohol dehydrogenases, class III. (356 aa)
SU9_17110Hypothetical protein; COG1042 Acyl-CoA synthetase (NDP forming). (751 aa)
SU9_17665COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (140 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
SU9_18301COG1737 Transcriptional regulators. (336 aa)
SU9_18558Hypothetical protein. (378 aa)
SU9_19075Putative oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (481 aa)
SU9_19334COG1940 Transcriptional regulator/sugar kinase. (74 aa)
SU9_19339COG1940 Transcriptional regulator/sugar kinase. (306 aa)
SU9_19862Hypothetical protein. (295 aa)
SU9_20349Glycoside hydrolase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases. (439 aa)
SU9_20354ROK family protein; COG1940 Transcriptional regulator/sugar kinase. (381 aa)
SU9_20713Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. (214 aa)
SU9_20863Mycothiol-dependent formaldehyde dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III. (361 aa)
SU9_20873Glycoside hydrolase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases. (446 aa)
SU9_21098Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (893 aa)
SU9_21507Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (348 aa)
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (910 aa)
SU9_22000COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa)
SU9_22095COG1062 Zn-dependent alcohol dehydrogenases, class III. (358 aa)
SU9_227102-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
SU9_22725COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (462 aa)
SU9_22975Glucokinase; COG1940 Transcriptional regulator/sugar kinase. (313 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
SU9_23440Hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (221 aa)
SU9_23630COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
SU9_23695Secreted protein; COG2951 Membrane-bound lytic murein transglycosylase B. (304 aa)
SU9_23917COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgiCOG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. (550 aa)
SU9_25524Mycothiol-dependent formaldehyde dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III. (361 aa)
SU9_25919COG1064 Zn-dependent alcohol dehydrogenases. (341 aa)
SU9_27554Hypothetical protein. (346 aa)
SU9_28184Phosphoenolpyruvate-dependent sugar phosphotransferase; COG2190 Phosphotransferase system IIA components. (149 aa)
SU9_28289Mycothiol-dependent formaldehyde dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III. (361 aa)
SU9_29131COG1940 Transcriptional regulator/sugar kinase. (398 aa)
SU9_29176COG1940 Transcriptional regulator/sugar kinase. (318 aa)
SU9_29341COG1940 Transcriptional regulator/sugar kinase. (352 aa)
SU9_30754Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase. (232 aa)
SU9_31001COG1062 Zn-dependent alcohol dehydrogenases, class III. (366 aa)
SU9_31006COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (464 aa)
SU9_31688COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (509 aa)
SU9_32068COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria). (671 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
SU9_03176ROK family glucokinase; COG1940 Transcriptional regulator/sugar kinase. (373 aa)
SU9_04421COG1940 Transcriptional regulator/sugar kinase. (399 aa)
SU9_04441Putative ATP/GTP-binding protein; COG3537 Putative alpha-1,2-mannosidase. (1140 aa)
SU9_05331GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (1033 aa)
SU9_05491Hypothetical protein; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. (219 aa)
SU9_06055COG1012 NAD-dependent aldehyde dehydrogenases. (486 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
SU9_07320COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
SU9_09009Polyphosphate glucokinase; COG1940 Transcriptional regulator/sugar kinase. (297 aa)
glpXCOG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. (343 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
SU9_09444Glucose kinase; COG1940 Transcriptional regulator/sugar kinase. (279 aa)
SU9_09949COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa)
SU9_11518Sugar kinase; COG1940 Transcriptional regulator/sugar kinase. (308 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
SU9_13439COG1064 Zn-dependent alcohol dehydrogenases. (351 aa)
SU9_14636COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (397 aa)
SU9_14641Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (344 aa)
SU9_14646Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (521 aa)
SU9_14706COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (404 aa)
SU9_14711Transketolase central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (327 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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