STRINGSTRING
SU9_00620 SU9_00620 SU9_00950 SU9_00950 SU9_01135 SU9_01135 SU9_01160 SU9_01160 SU9_01205 SU9_01205 SU9_02576 SU9_02576 SU9_02676 SU9_02676 SU9_02706 SU9_02706 SU9_03206 SU9_03206 SU9_03281 SU9_03281 SU9_03541 SU9_03541 SU9_03701 SU9_03701 SU9_04686 SU9_04686 SU9_05301 SU9_05301 SU9_05331 SU9_05331 SU9_06055 SU9_06055 SU9_06410 SU9_06410 SU9_06665 SU9_06665 SU9_06785 SU9_06785 SU9_07310 SU9_07310 ackA ackA SU9_07320 SU9_07320 SU9_07465 SU9_07465 SU9_07960 SU9_07960 SU9_09059 SU9_09059 fumC fumC SU9_09294 SU9_09294 pckG pckG SU9_09949 SU9_09949 mdh mdh acsA acsA SU9_13044 SU9_13044 SU9_13049 SU9_13049 SU9_13284 SU9_13284 SU9_13765 SU9_13765 SU9_13865 SU9_13865 SU9_14566 SU9_14566 SU9_14636 SU9_14636 SU9_14641 SU9_14641 SU9_14646 SU9_14646 SU9_14706 SU9_14706 SU9_14711 SU9_14711 SU9_14716 SU9_14716 SU9_14726 SU9_14726 SU9_15664 SU9_15664 SU9_16457 SU9_16457 SU9_16462 SU9_16462 SU9_17110 SU9_17110 SU9_17135 SU9_17135 SU9_17160 SU9_17160 SU9_17655 SU9_17655 SU9_17665 SU9_17665 SU9_18014 SU9_18014 ppc ppc SU9_18221 SU9_18221 SU9_18920 SU9_18920 SU9_19075 SU9_19075 SU9_19459 SU9_19459 SU9_20868 SU9_20868 leuA leuA SU9_21098 SU9_21098 aceE aceE SU9_21965 SU9_21965 SU9_21995 SU9_21995 SU9_22000 SU9_22000 SU9_22295 SU9_22295 SU9_22300 SU9_22300 SU9_22710 SU9_22710 SU9_22725 SU9_22725 SU9_23020 SU9_23020 SU9_23565 SU9_23565 SU9_23630 SU9_23630 SU9_23842 SU9_23842 SU9_24772 SU9_24772 SU9_25154 SU9_25154 SU9_25244 SU9_25244 SU9_25289 SU9_25289 SU9_26064 SU9_26064 SU9_26074 SU9_26074 SU9_26599 SU9_26599 SU9_26714 SU9_26714 SU9_26884 SU9_26884 SU9_27284 SU9_27284 SU9_27439 SU9_27439 SU9_27554 SU9_27554 SU9_28114 SU9_28114 SU9_28119 SU9_28119 SU9_28436 SU9_28436 SU9_28486 SU9_28486 SU9_28536 SU9_28536 SU9_28566 SU9_28566 SU9_29271 SU9_29271 SU9_29296 SU9_29296 SU9_29876 SU9_29876 SU9_31006 SU9_31006 SU9_31688 SU9_31688 SU9_32068 SU9_32068 SU9_32438 SU9_32438 SU9_32878 SU9_32878 SU9_33123 SU9_33123 SU9_33223 SU9_33223 SU9_33913 SU9_33913
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SU9_00620COG3030 Protein affecting phage T7 exclusion by the F plasmid. (171 aa)
SU9_00950COG3564 Uncharacterized protein conserved in bacteria. (141 aa)
SU9_01135COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. (389 aa)
SU9_01160COG1254 Acylphosphatases. (83 aa)
SU9_01205Lyase; COG0346 Lactoylglutathione lyase and related lyases. (157 aa)
SU9_02576Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (263 aa)
SU9_02676Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. (110 aa)
SU9_02706Bleomycin resistance protein. (131 aa)
SU9_03206Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (132 aa)
SU9_03281COG2225 Malate synthase; Belongs to the malate synthase family. (542 aa)
SU9_03541Pyruvate dehydrogenase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (580 aa)
SU9_03701Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria. (127 aa)
SU9_04686Hydroxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (266 aa)
SU9_05301Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (258 aa)
SU9_05331GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (1033 aa)
SU9_06055COG1012 NAD-dependent aldehyde dehydrogenases. (486 aa)
SU9_06410COG1254 Acylphosphatases. (93 aa)
SU9_06665Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (544 aa)
SU9_06785NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (325 aa)
SU9_07310Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa)
ackAAcetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (406 aa)
SU9_07320COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
SU9_07465Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
SU9_07960Malate oxidoreductase; COG0281 Malic enzyme. (407 aa)
SU9_09059Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (557 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (473 aa)
SU9_09294Glyoxalase/bleomycin resistance protein/dioxygenase. (122 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
SU9_09949COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
SU9_13044Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases. (278 aa)
SU9_13049Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (313 aa)
SU9_13284Beta-lactamase domain-containing protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (298 aa)
SU9_13765GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (183 aa)
SU9_13865Dyp-type peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (411 aa)
SU9_14566Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase. (109 aa)
SU9_14636COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (397 aa)
SU9_14641Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (344 aa)
SU9_14646Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (521 aa)
SU9_14706COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (404 aa)
SU9_14711Transketolase central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (327 aa)
SU9_14716Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (490 aa)
SU9_14726Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria. (137 aa)
SU9_15664DNA-binding protein; COG2452 Predicted site-specific integrase-resolvase. (68 aa)
SU9_16457COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (364 aa)
SU9_16462Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (650 aa)
SU9_17110Hypothetical protein; COG1042 Acyl-CoA synthetase (NDP forming). (751 aa)
SU9_17135Glyoxalase/bleomycin resistance protein dioxygenase superfamily protein; COG3324 Predicted enzyme related to lactoylglutathione lyase. (266 aa)
SU9_17160Hypothetical protein. (156 aa)
SU9_17655Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases. (567 aa)
SU9_17665COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (140 aa)
SU9_18014Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. (122 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (921 aa)
SU9_18221COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
SU9_18920NAD-binding malic protein; COG0281 Malic enzyme. (477 aa)
SU9_19075Putative oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (481 aa)
SU9_19459NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
SU9_20868Beta-lactamase; COG0491 Zn-dependent hydrolases, including glyoxylases. (209 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (592 aa)
SU9_21098Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (893 aa)
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (910 aa)
SU9_21965COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
SU9_21995COG0491 Zn-dependent hydrolases, including glyoxylases. (349 aa)
SU9_22000COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa)
SU9_22295Hypothetical protein; COG0672 High-affinity Fe2+/Pb2+ permease. (330 aa)
SU9_22300Tat-translocated protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (444 aa)
SU9_227102-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
SU9_22725COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (462 aa)
SU9_23020COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
SU9_23565Beta-lactamase; COG0491 Zn-dependent hydrolases, including glyoxylases. (243 aa)
SU9_23630COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
SU9_23842Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases. (218 aa)
SU9_24772COG0777 Acetyl-CoA carboxylase beta subunit. (479 aa)
SU9_25154Hypothetical protein. (148 aa)
SU9_25244SgaA protein; COG3324 Predicted enzyme related to lactoylglutathione lyase. (239 aa)
SU9_25289COG0845 Membrane-fusion protein. (268 aa)
SU9_26064Tat-translocated protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (416 aa)
SU9_26074Hypothetical protein. (134 aa)
SU9_26599Beta-lactamase domain-containing protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (301 aa)
SU9_26714COG2764 Uncharacterized protein conserved in bacteria. (138 aa)
SU9_26884Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1124 aa)
SU9_27284Beta-lactamase domain-containing protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (304 aa)
SU9_27439Hypothetical protein; COG0439 Biotin carboxylase. (418 aa)
SU9_27554Hypothetical protein. (346 aa)
SU9_28114Hypothetical protein. (80 aa)
SU9_28119Putative transposase for IS112. (163 aa)
SU9_28436COG0183 Acetyl-CoA acetyltransferase. (388 aa)
SU9_28486Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (265 aa)
SU9_28536Hydroxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (254 aa)
SU9_28566Hypothetical protein; COG0439 Biotin carboxylase. (396 aa)
SU9_29271Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (128 aa)
SU9_29296Lyase; COG0346 Lactoylglutathione lyase and related lyases. (132 aa)
SU9_29876Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases. (237 aa)
SU9_31006COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (464 aa)
SU9_31688COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (509 aa)
SU9_32068COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria). (671 aa)
SU9_32438Tat-translocated enzyme; COG2837 Predicted iron-dependent peroxidase. (392 aa)
SU9_32878Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (114 aa)
SU9_33123Dyp-type peroxidase family protein; COG2837 Predicted iron-dependent peroxidase. (312 aa)
SU9_33223Glyoxalase family protein; COG3324 Predicted enzyme related to lactoylglutathione lyase. (118 aa)
SU9_33913Transposase IS4 family protein. (167 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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