STRINGSTRING
SU9_06650 SU9_06650 SU9_00170 SU9_00170 SU9_00775 SU9_00775 SU9_00950 SU9_00950 SU9_01925 SU9_01925 SU9_02434 SU9_02434 SU9_02439 SU9_02439 SU9_02746 SU9_02746 SU9_02826 SU9_02826 SU9_02856 SU9_02856 SU9_03221 SU9_03221 SU9_03281 SU9_03281 SU9_03331 SU9_03331 SU9_03336 SU9_03336 SU9_03341 SU9_03341 SU9_04061 SU9_04061 SU9_04446 SU9_04446 SU9_04706 SU9_04706 SU9_04891 SU9_04891 SU9_05371 SU9_05371 SU9_05376 SU9_05376 SU9_06415 SU9_06415 SU9_06785 SU9_06785 SU9_06860 SU9_06860 gcvT gcvT gcvH gcvH glyA glyA SU9_07390 SU9_07390 SU9_07465 SU9_07465 SU9_07470 SU9_07470 glyA-3 glyA-3 SU9_08262 SU9_08262 SU9_09089 SU9_09089 SU9_09834 SU9_09834 SU9_09874 SU9_09874 SU9_10219 SU9_10219 glyA-2 glyA-2 mdh mdh SU9_10878 SU9_10878 purU purU SU9_11103 SU9_11103 SU9_11128 SU9_11128 SU9_11208 SU9_11208 SU9_11358 SU9_11358 acsA acsA SU9_15292 SU9_15292 SU9_15664 SU9_15664 SU9_16577 SU9_16577 SU9_17070 SU9_17070 SU9_17665 SU9_17665 SU9_18221 SU9_18221 SU9_18683 SU9_18683 SU9_19060 SU9_19060 SU9_19075 SU9_19075 SU9_19354 SU9_19354 SU9_19459 SU9_19459 SU9_19640 SU9_19640 gltA gltA SU9_20032 SU9_20032 SU9_20504 SU9_20504 SU9_21697 SU9_21697 SU9_21965 SU9_21965 SU9_22130 SU9_22130 SU9_22455 SU9_22455 SU9_22600 SU9_22600 SU9_22645 SU9_22645 SU9_22725 SU9_22725 SU9_23675 SU9_23675 gcvP gcvP SU9_27214 SU9_27214 SU9_27219 SU9_27219 SU9_27374 SU9_27374 SU9_28436 SU9_28436 SU9_29351 SU9_29351 SU9_30444 SU9_30444 SU9_30859 SU9_30859 SU9_31718 SU9_31718 SU9_32563 SU9_32563 glyA-4 glyA-4 purU-2 purU-2 SU9_33353 SU9_33353
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_06650COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (527 aa)
SU9_00170COG2340 Uncharacterized protein with SCP/PR1 domains. (188 aa)
SU9_00775Hypothetical protein. (322 aa)
SU9_00950COG3564 Uncharacterized protein conserved in bacteria. (141 aa)
SU9_01925COG0174 Glutamine synthetase. (465 aa)
SU9_02434COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (627 aa)
SU9_02439COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (743 aa)
SU9_02746Peptidase U61 LD-carboxypeptidase A; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF. (310 aa)
SU9_02826COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (667 aa)
SU9_02856COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (374 aa)
SU9_03221COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (222 aa)
SU9_03281COG2225 Malate synthase; Belongs to the malate synthase family. (542 aa)
SU9_03331Oxidoreductase; COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family. (279 aa)
SU9_033362-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (298 aa)
SU9_03341COG0753 Catalase; Belongs to the catalase family. (493 aa)
SU9_04061COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (289 aa)
SU9_04446Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
SU9_04706HAD-superfamily hydrolase; COG0546 Predicted phosphatases. (240 aa)
SU9_04891COG2030 Acyl dehydratase. (142 aa)
SU9_05371COG0372 Citrate synthase; Belongs to the citrate synthase family. (389 aa)
SU9_05376Citrate synthase-like protein; COG0372 Citrate synthase. (415 aa)
SU9_06415COG2340 Uncharacterized protein with SCP/PR1 domains. (294 aa)
SU9_06785NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (325 aa)
SU9_06860Hypothetical protein. (554 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (366 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
SU9_07390COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (566 aa)
SU9_07465Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
SU9_07470methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (146 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (459 aa)
SU9_08262Catalase related subgroup domain-containing protein; COG0753 Catalase; Belongs to the catalase family. (487 aa)
SU9_09089COG0753 Catalase; Belongs to the catalase family. (486 aa)
SU9_09834COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (529 aa)
SU9_09874COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (589 aa)
SU9_10219COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (532 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa)
SU9_10878Cobalamin B12-binding domain-containing protein; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding). (128 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (296 aa)
SU9_11103COG0372 Citrate synthase; Belongs to the citrate synthase family. (367 aa)
SU9_11128Acetyl/propionyl CoA carboxylase subunit alpha; COG0439 Biotin carboxylase. (647 aa)
SU9_11208FAD linked oxidase domain-containing protein; COG0277 FAD/FMN-containing dehydrogenases. (981 aa)
SU9_11358Haloacid dehalogenase; COG0546 Predicted phosphatases. (221 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
SU9_15292Hypothetical protein. (52 aa)
SU9_15664DNA-binding protein; COG2452 Predicted site-specific integrase-resolvase. (68 aa)
SU9_16577Hypothetical protein; COG2030 Acyl dehydratase. (144 aa)
SU9_17070Cyclase; COG1878 Predicted metal-dependent hydrolase. (308 aa)
SU9_17665COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (140 aa)
SU9_18221COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
SU9_18683Phosphatase; COG0546 Predicted phosphatases. (220 aa)
SU9_19060Putative oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. (454 aa)
SU9_19075Putative oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (481 aa)
SU9_19354Hydrolase; COG0546 Predicted phosphatases. (236 aa)
SU9_19459NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
SU9_19640COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (670 aa)
gltACOG0372 Citrate synthase; Belongs to the citrate synthase family. (429 aa)
SU9_20032COG0174 Glutamine synthetase. (435 aa)
SU9_20504Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. (128 aa)
SU9_216972-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (206 aa)
SU9_21965COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
SU9_221302-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (214 aa)
SU9_22455COG0174 Glutamine synthetase. (453 aa)
SU9_22600Glutamate--ammonia ligase; COG0174 Glutamine synthetase. (340 aa)
SU9_22645COG0174 Glutamine synthetase. (469 aa)
SU9_22725COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (462 aa)
SU9_23675COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
SU9_27214Putative RNA polymerase ECF-subfamily sigma factor; COG2340 Uncharacterized protein with SCP/PR1 domains. (306 aa)
SU9_27219Hypothetical protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (504 aa)
SU9_27374COG2340 Uncharacterized protein with SCP/PR1 domains. (119 aa)
SU9_28436COG0183 Acetyl-CoA acetyltransferase. (388 aa)
SU9_29351Hydrolase; COG0546 Predicted phosphatases. (263 aa)
SU9_30444COG0174 Glutamine synthetase. (462 aa)
SU9_30859Hypothetical protein; COG2864 Cytochrome b subunit of formate dehydrogenase. (234 aa)
SU9_31718COG0277 FAD/FMN-containing dehydrogenases. (984 aa)
SU9_32563COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family. (593 aa)
glyA-4Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (304 aa)
SU9_33353Putative methylmalonyl-CoA decarboxylase subunit alpha; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (529 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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