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SU9_09949 SU9_09949 SU9_07440 SU9_07440 SU9_07400 SU9_07400 SU9_06775 SU9_06775 ilvH ilvH ilvC ilvC SU9_06705 SU9_06705 coaD coaD SU9_06055 SU9_06055 SU9_05136 SU9_05136 SU9_04866 SU9_04866 SU9_04626 SU9_04626 acpS-2 acpS-2 SU9_29711 SU9_29711 SU9_30056 SU9_30056 SU9_31006 SU9_31006 SU9_31688 SU9_31688 SU9_20072 SU9_20072 SU9_19732 SU9_19732 SU9_18004 SU9_18004 SU9_17540 SU9_17540 acpS acpS coaA coaA SU9_15934 SU9_15934 SU9_14151 SU9_14151 SU9_13650 SU9_13650 SU9_13558 SU9_13558 SU9_12742 SU9_12742 SU9_12322 SU9_12322 panC panC coaX coaX ilvD ilvD SU9_11263 SU9_11263 SU9_10099 SU9_10099 SU9_00475 SU9_00475 SU9_01120 SU9_01120 SU9_02369 SU9_02369 SU9_02951 SU9_02951 SU9_02966 SU9_02966 SU9_02971 SU9_02971 SU9_03711 SU9_03711 SU9_21093 SU9_21093 SU9_21292 SU9_21292 SU9_21815 SU9_21815 SU9_22000 SU9_22000 panB panB SU9_23540 SU9_23540 coaE coaE SU9_27204 SU9_27204 SU9_28024 SU9_28024
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_09949COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa)
SU9_07440Regulatory protein MarR; COG1846 Transcriptional regulators. (158 aa)
SU9_07400COG1846 Transcriptional regulators. (169 aa)
SU9_06775Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (622 aa)
ilvHCOG0440 Acetolactate synthase, small (regulatory) subunit. (174 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
SU9_06705COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (368 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
SU9_06055COG1012 NAD-dependent aldehyde dehydrogenases. (486 aa)
SU9_05136Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (593 aa)
SU9_04866COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (186 aa)
SU9_04626COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); Belongs to the P-Pant transferase superfamily. (134 aa)
acpS-2Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (137 aa)
SU9_29711Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (411 aa)
SU9_30056COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (274 aa)
SU9_31006COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (464 aa)
SU9_31688COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (509 aa)
SU9_20072COG1846 Transcriptional regulators. (169 aa)
SU9_19732Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (557 aa)
SU9_18004COG1846 Transcriptional regulators. (165 aa)
SU9_17540COG1846 Transcriptional regulators. (165 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa)
coaACOG1072 Panthothenate kinase. (327 aa)
SU9_15934COG1846 Transcriptional regulators. (186 aa)
SU9_14151Regulatory protein MarR; COG1846 Transcriptional regulators. (170 aa)
SU9_13650COG1846 Transcriptional regulators. (160 aa)
SU9_13558COG1846 Transcriptional regulators. (168 aa)
SU9_12742COG1846 Transcriptional regulators. (161 aa)
SU9_12322Putative oxidoreductase/dehydrogenase, Rossmann-like domain-containing protein. (323 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (436 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (265 aa)
ilvDCOG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (616 aa)
SU9_11263COG1846 Transcriptional regulators. (154 aa)
SU9_10099COG1324 Uncharacterized protein involved in tolerance to divalent cations. (90 aa)
SU9_00475COG1846 Transcriptional regulators. (145 aa)
SU9_01120COG1846 Transcriptional regulators. (157 aa)
SU9_02369COG1846 Transcriptional regulators. (168 aa)
SU9_02951Phenylhydantoinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. (468 aa)
SU9_02966Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COG0388 Predicted amidohydrolase. (280 aa)
SU9_02971Regulatory protein MarR; COG1846 Transcriptional regulators. (143 aa)
SU9_03711Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. (183 aa)
SU9_21093COG1846 Transcriptional regulators. (191 aa)
SU9_21292COG1324 Uncharacterized protein involved in tolerance to divalent cations. (121 aa)
SU9_21815Nucleoside triphosphate hydrolase domain-containing protein; COG1072 Panthothenate kinase. (218 aa)
SU9_22000COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (483 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (286 aa)
SU9_23540COG1846 Transcriptional regulators. (193 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa)
SU9_27204COG1846 Transcriptional regulators. (169 aa)
SU9_28024COG1846 Transcriptional regulators. (149 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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