STRINGSTRING
SU9_27874 SU9_27874 SU9_00175 SU9_00175 SU9_00240 SU9_00240 SU9_00600 SU9_00600 SU9_00620 SU9_00620 SU9_02055 SU9_02055 SU9_02651 SU9_02651 SU9_03051 SU9_03051 SU9_04446 SU9_04446 SU9_04906 SU9_04906 SU9_05136 SU9_05136 SU9_05371 SU9_05371 SU9_05376 SU9_05376 SU9_05551 SU9_05551 SU9_06030 SU9_06030 leuD leuD leuC leuC SU9_06665 SU9_06665 SU9_06705 SU9_06705 leuB leuB ilvC ilvC ilvH ilvH SU9_06775 SU9_06775 SU9_08649 SU9_08649 SU9_09344 SU9_09344 SU9_10668 SU9_10668 SU9_11103 SU9_11103 SU9_11950 SU9_11950 ilvD ilvD SU9_12282 SU9_12282 asd asd SU9_13179 SU9_13179 SU9_13324 SU9_13324 SU9_14156 SU9_14156 SU9_16592 SU9_16592 SU9_17305 SU9_17305 SU9_19732 SU9_19732 gltA gltA asd-2 asd-2 leuA leuA SU9_21382 SU9_21382 SU9_21875 SU9_21875 SU9_24162 SU9_24162 SU9_24757 SU9_24757 SU9_24827 SU9_24827 SU9_25224 SU9_25224 SU9_25324 SU9_25324 SU9_27569 SU9_27569 SU9_29301 SU9_29301 SU9_30056 SU9_30056 argD argD argB argB argJ argJ argC argC SU9_30309 SU9_30309 SU9_33003 SU9_33003
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_27874Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (263 aa)
SU9_00175COG0456 Acetyltransferases. (141 aa)
SU9_00240GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (441 aa)
SU9_00600COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (501 aa)
SU9_00620COG3030 Protein affecting phage T7 exclusion by the F plasmid. (171 aa)
SU9_02055N-acetyltransferase; COG3393 Predicted acetyltransferase. (285 aa)
SU9_02651Putative aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (404 aa)
SU9_03051COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (442 aa)
SU9_04446Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
SU9_04906COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (508 aa)
SU9_05136Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (593 aa)
SU9_05371COG0372 Citrate synthase; Belongs to the citrate synthase family. (389 aa)
SU9_05376Citrate synthase-like protein; COG0372 Citrate synthase. (415 aa)
SU9_05551Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
SU9_06030Acetyltransferase; COG3393 Predicted acetyltransferase. (281 aa)
leuDIsopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa)
SU9_06665Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (544 aa)
SU9_06705COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (368 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (346 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
ilvHCOG0440 Acetolactate synthase, small (regulatory) subunit. (174 aa)
SU9_06775Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (622 aa)
SU9_08649GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (345 aa)
SU9_09344Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (403 aa)
SU9_10668COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (483 aa)
SU9_11103COG0372 Citrate synthase; Belongs to the citrate synthase family. (367 aa)
SU9_11950Acetyltransferase-like protein; COG3393 Predicted acetyltransferase. (284 aa)
ilvDCOG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (616 aa)
SU9_12282COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. (163 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (376 aa)
SU9_13179COG0527 Aspartokinases; Belongs to the aspartokinase family. (423 aa)
SU9_13324COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase). (322 aa)
SU9_14156Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (150 aa)
SU9_16592COG0436 Aspartate/tyrosine/aromatic aminotransferase. (411 aa)
SU9_17305Aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (407 aa)
SU9_19732Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. (557 aa)
gltACOG0372 Citrate synthase; Belongs to the citrate synthase family. (429 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (592 aa)
SU9_21382Amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (421 aa)
SU9_21875COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (161 aa)
SU9_24162Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
SU9_24757COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (404 aa)
SU9_24827Acetyltransferase; COG3393 Predicted acetyltransferase. (245 aa)
SU9_25224COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (294 aa)
SU9_25324N-acetyltransferase GCN5; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (181 aa)
SU9_27569N-acetyltransferase GCN5; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (253 aa)
SU9_29301COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa)
SU9_30056COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (274 aa)
argDCOG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (309 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (383 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa)
SU9_30309COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (456 aa)
SU9_33003Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (372 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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