STRINGSTRING
SU9_14361 SU9_14361 SU9_18111 SU9_18111 recD2 recD2 SU9_20052 SU9_20052 SU9_20254 SU9_20254 SU9_20778 SU9_20778 recO recO SU9_21637 SU9_21637 SU9_21642 SU9_21642 SU9_22705 SU9_22705 dnaE dnaE polA polA SU9_23772 SU9_23772 SU9_23827 SU9_23827 SU9_23832 SU9_23832 SU9_24092 SU9_24092 SU9_24362 SU9_24362 SU9_25279 SU9_25279 SU9_27729 SU9_27729 priA-2 priA-2 ruvB ruvB ruvA ruvA ruvC ruvC SU9_30011 SU9_30011 SU9_30494 SU9_30494 SU9_30544 SU9_30544 SU9_30549 SU9_30549 SU9_30779 SU9_30779 SU9_31171 SU9_31171 SU9_31271 SU9_31271 SU9_33833 SU9_33833 SU9_14216 SU9_14216 SU9_13900 SU9_13900 SU9_13199 SU9_13199 recR recR SU9_12979 SU9_12979 SU9_12867 SU9_12867 SU9_12832 SU9_12832 SU9_12612 SU9_12612 SU9_11558 SU9_11558 SU9_11368 SU9_11368 SU9_10414 SU9_10414 SU9_10379 SU9_10379 SU9_08329 SU9_08329 SU9_07840 SU9_07840 SU9_06465 SU9_06465 recA recA SU9_05506 SU9_05506 SU9_05181 SU9_05181 SU9_04151 SU9_04151 SU9_03491 SU9_03491 SU9_14842 SU9_14842 recF recF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SU9_14361DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (376 aa)
SU9_18111Putative lipoprotein; COG0760 Parvulin-like peptidyl-prolyl isomerase. (212 aa)
recD2RecD/TraA family helicase; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (736 aa)
SU9_20052Von Willebrand factor A. (256 aa)
SU9_20254COG0629 Single-stranded DNA-binding protein. (243 aa)
SU9_20778COG1466 DNA polymerase III, delta subunit. (327 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (248 aa)
SU9_21637Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (191 aa)
SU9_21642Tellurium resistance protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (191 aa)
SU9_22705COG2378 Predicted transcriptional regulator. (342 aa)
dnaECOG0587 DNA polymerase III, alpha subunit. (1185 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (912 aa)
SU9_23772Hypothetical protein. (654 aa)
SU9_23827Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (192 aa)
SU9_23832Export associated protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (695 aa)
SU9_24092Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (410 aa)
SU9_24362COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (337 aa)
SU9_25279Hypothetical protein; COG1796 DNA polymerase IV (family X). (343 aa)
SU9_27729COG2378 Predicted transcriptional regulator. (246 aa)
priA-2Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (694 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (363 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (206 aa)
ruvCHolliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (192 aa)
SU9_30011COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (241 aa)
SU9_30494COG0258 5'-3' exonuclease (including N-terminal domain of PolI). (304 aa)
SU9_30544Hypothetical protein; COG2378 Predicted transcriptional regulator. (316 aa)
SU9_30549Transcriptional regulator-like protein; COG2378 Predicted transcriptional regulator. (322 aa)
SU9_30779Hypothetical protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (868 aa)
SU9_31171COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1195 aa)
SU9_31271Putative transcriptional repressor; COG2378 Predicted transcriptional regulator. (344 aa)
SU9_33833Toxic cation resistance protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (394 aa)
SU9_14216COG0629 Single-stranded DNA-binding protein. (196 aa)
SU9_13900COG0789 Predicted transcriptional regulators. (323 aa)
SU9_13199COG2812 DNA polymerase III, gamma/tau subunits. (751 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
SU9_12979Hypothetical protein. (265 aa)
SU9_12867DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. (416 aa)
SU9_12832Mobilization relaxase component. (571 aa)
SU9_12612COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains. (534 aa)
SU9_11558Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (191 aa)
SU9_11368Hypothetical protein. (838 aa)
SU9_10414Hypothetical protein. (238 aa)
SU9_10379COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains. (631 aa)
SU9_08329COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (570 aa)
SU9_07840Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. (165 aa)
SU9_06465ATP-dependent DNA helicase; COG1200 RecG-like helicase. (1010 aa)
recARecombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (373 aa)
SU9_05506Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1. (173 aa)
SU9_05181OB-fold tRNA/helicase-type nucleic acid binding protein; COG0183 Acetyl-CoA acetyltransferase. (132 aa)
SU9_04151COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (239 aa)
SU9_03491Iron transport protein; COG4264 Siderophore synthetase component. (528 aa)
SU9_14842Toxic cation resistance protein. (529 aa)
recFRecombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (378 aa)
Your Current Organism:
Streptomyces auratus
NCBI taxonomy Id: 1160718
Other names: S. auratus AGR0001, Streptomyces auratus AGR0001, Streptomyces auratus str. AGR0001, Streptomyces auratus strain AGR0001
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