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| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (436 aa) |
| | atpB-2 | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (287 aa) |
| | atpE-2 | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (77 aa) |
| | atpF-2 | F-type H+-transporting ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa) |
| | atpH | ATP synthase F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa) |
| | atpF1A | F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (511 aa) |
| | atpF1G | ATP synthase F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa) |
| | atpD-2 | ATP synthase F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (458 aa) |
| | atpC-2 | ATP synthase F1 subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa) |
| | BAN36804.1 | MoeB/ThiF-like protein. (285 aa) |
| | dgt | Deoxyguanosinetriphosphate triphosphohydrolase-like protein; K01129; Belongs to the dGTPase family. Type 2 subfamily. (374 aa) |
| | thiE | Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa) |
| | BAN36726.1 | Phosphomethylpyrimidine kinase; K00941. (279 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (623 aa) |
| | BAN36688.1 | Family 2 glycosyl transferase; K00721. (316 aa) |
| | pfkA | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (371 aa) |
| | fbaA-2 | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | pyk | Pyruvate kinase; K00873; Belongs to the pyruvate kinase family. (480 aa) |
| | pgk | Phosphoglycerate kinase; K00927; Belongs to the phosphoglycerate kinase family. (393 aa) |
| | BAN36642.1 | Inositol monophosphatase; K01092. (260 aa) |
| | BAN36632.1 | Hypothetical protein. (474 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa) |
| | BAN36576.1 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa) |
| | BAN36572.1 | Phospholipid/glycerol acyltransferase; K00655. (277 aa) |
| | BAN36566.1 | AMP-dependent synthetase and ligase. (447 aa) |
| | BAN36554.1 | Family 2 glycosyl transferase. (254 aa) |
| | BAN36553.1 | Phospholipid/glycerol acyltransferase. (266 aa) |
| | BAN36501.1 | Adenylyltransferase; K11996. (251 aa) |
| | gpmI | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa) |
| | gpsA | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (327 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (276 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | corC | CBS domain-containing protein; K06189. (281 aa) |
| | BAN36368.1 | Phospholipid/glycerol acyltransferase; K00655. (238 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (341 aa) |
| | cbbE | Ribulose-5-phosphate 3-epimerase; K01783; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (240 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (196 aa) |
| | pyrC-2 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (345 aa) |
| | lpxC | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (304 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa) |
| | plsY | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (207 aa) |
| | soxB | Sulfate thiol esterase SoxB; Belongs to the 5'-nucleotidase family. (571 aa) |
| | BAN36187.1 | Putative endonuclease protein. (193 aa) |
| | ygjP | Hypothetical protein; K07043. (170 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (213 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; K01933. (349 aa) |
| | BAN36124.1 | Hypothetical protein. (91 aa) |
| | BAN36085.1 | Molybdopterin binding domain-containing protein. (246 aa) |
| | atpC | ATP synthase, F1 epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (147 aa) |
| | BAN36081.1 | Hypothetical protein. (226 aa) |
| | BAN36033.1 | HAD family hydrolase. (221 aa) |
| | BAN36027.1 | Deoxynucleoside kinase; K15518. (213 aa) |
| | BAN36013.1 | Adenylosuccinate lyase; K01756; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (623 aa) |
| | folE2 | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. (271 aa) |
| | BAN35998.1 | Ferredoxin. (345 aa) |
| | BAN35941.1 | Riboflavin biosynthesis protein RibF; K11753; Belongs to the ribF family. (308 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (311 aa) |
| | BAN35930.1 | Glycine oxidase ThiO; K03153. (343 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa) |
| | BAN35898.1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (375 aa) |
| | BAN35876.1 | Hypothetical protein. (351 aa) |
| | BAN35857.1 | Alpha-ribazole phosphatase; K02226. (202 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923; Belongs to the SAICAR synthetase family. (292 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (400 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa) |
| | BAN35849.1 | Ketose-bisphosphate aldolase; K01624. (391 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (346 aa) |
| | acs | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (208 aa) |
| | pgi | Glucose-6-phosphate isomerase; K01810; Belongs to the GPI family. (547 aa) |
| | BAN35712.1 | Metallophosphoesterase. (262 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (319 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (419 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (535 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (322 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
| | ispG | Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (363 aa) |
| | BAN35595.1 | Hypothetical protein. (135 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (230 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | BAN35570.1 | Polysaccharide deacetylase; K13014. (302 aa) |
| | BAN35567.1 | Family 2 glycosyl transferase; K10012. (312 aa) |
| | BAN35565.1 | Hypothetical protein. (123 aa) |
| | BAN35564.1 | Glycosyl transferase family 39; K07264. (551 aa) |
| | BAN35563.1 | Phosphoesterase, PA-phosphatase related protein. (267 aa) |
| | BAN35562.1 | Glycosyl transferase family 39. (514 aa) |
| | BAN35560.1 | Undecaprenylphosphate 4-deoxyformamido-L-arabinose transferase; K00721. (339 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | BAN35496.1 | Lactoylglutathione lyase-like lyase; K08234. (132 aa) |
| | BAN35485.1 | Phosphoribosyltransferase; K00760. (182 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa) |
| | BAN35451.1 | Phosphatidate cytidylyltransferase; K00981; Belongs to the CDS family. (273 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (397 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (350 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl carrier protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (144 aa) |
| | lpxA | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (378 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (553 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (399 aa) |
| | BAN35363.1 | Maf protein, putative; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (191 aa) |
| | BAN35361.1 | Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (472 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein plsx; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (338 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (153 aa) |
| | prpE | Propionate--CoA ligase; K01908. (635 aa) |
| | sucB | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (396 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1349 aa) |
| | nnrE | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (495 aa) |
| | BAN35215.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (528 aa) |
| | BAN35123.1 | CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; K00995; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (190 aa) |
| | moaA1 | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa) |
| | glk | Glucokinase; K00845; Belongs to the bacterial glucokinase family. (331 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa) |
| | BAN35103.1 | Molybdopterin-guanine dinucleotide biosynthesis protein MobB; K03753. (167 aa) |
| | BAN35102.1 | Molybdopterin biosynthesis protein, molybdenum incorporation step; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (401 aa) |
| | BAN35101.1 | Molybdopterin synthase small subunit; K03636. (84 aa) |
| | BAN35100.1 | Molybdopterin converting factor, large subunit; K03635. (153 aa) |
| | BAN35079.1 | Inositol-1(or 4)-monophosphatase; K01092; Belongs to the inositol monophosphatase superfamily. (264 aa) |
| | BAN35059.1 | Flagellar protein export ATPase FliI; K02412. (466 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (501 aa) |
| | BAN35007.1 | 6-phosphogluconate dehydrogenase; K00033. (306 aa) |
| | BAN34974.1 | Serine--pyruvate transaminase; K00839. (393 aa) |
| | BAN34970.1 | Nicotinate-nucleotide pyrophosphorylase; K00767; Belongs to the NadC/ModD family. (278 aa) |
| | surE | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (245 aa) |
| | BAN34940.1 | (p)ppGpp synthetase I SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (728 aa) |
| | BAN34913.1 | Hypothetical protein. (221 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | cmk | Cytidylate kinase; K00945. (225 aa) |
| | BAN34857.1 | Hypothetical protein; K07141. (191 aa) |
| | BAN34831.1 | Metal dependent phosphohydrolase; K06952. (183 aa) |
| | fbaB | Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; K11645. (349 aa) |
| | BAN34793.1 | Hypothetical protein; K01515. (185 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit; K01955; Belongs to the CarB family. (1069 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; K01956; Belongs to the CarA family. (376 aa) |
| | nadK | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (290 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (499 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa) |
| | BAN34699.1 | Hypothetical protein. (425 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (885 aa) |
| | BAN34695.1 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (437 aa) |
| | BAN34688.1 | CinA domain-containing protein; K03743; Belongs to the CinA family. (161 aa) |
| | BAN34686.1 | Thiamine-monophosphate kinase; K00946. (203 aa) |
| | BAN34685.1 | Thiamine-monophosphate kinase; K00946. (133 aa) |
| | mogA | Molybdopterin biosynthesis protein; K03831. (186 aa) |
| | BAN34663.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (255 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (226 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (159 aa) |
| | BAN34591.1 | Phosphopantothenate-cysteine ligase / phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (153 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (470 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (367 aa) |
| | BAN34551.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (206 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa) |
| | atpD | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (485 aa) |
| | BAN34541.1 | Alternate F1F0 ATPase, F1 subunit epsilon. (129 aa) |
| | atpB | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (230 aa) |
| | atpE | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (93 aa) |
| | atpF | H+-transporting two-sector ATPase, B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (268 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (556 aa) |
| | BAN34534.1 | H+-transporting two-sector ATPase subunit gamma. (294 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (195 aa) |
| | clsB | Phospholipase D/transphosphatidylase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (388 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (365 aa) |
| | BAN34380.1 | Thiamine biosynthesis protein ThiS; K03154. (66 aa) |
| | thiG | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (260 aa) |
| | folE | GTP cyclohydrolase I; K01495; Belongs to the GTP cyclohydrolase I family. (212 aa) |
| | BAN34366.1 | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (199 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (203 aa) |
| | BAN34359.1 | (p)ppGpp synthetase I SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (729 aa) |
| | cbbI | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (218 aa) |
| | napA | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (841 aa) |
| | BAN34107.1 | Hypothetical protein. (455 aa) |
| | algH | Hypothetical protein; K07735; Belongs to the UPF0301 (AlgH) family. (186 aa) |
| | pyrB | Aspartate carbamoyltransferase; K00609; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (326 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; K01465. (426 aa) |
| | BAN34017.1 | MazG nucleotide pyrophosphohydrolase; K16904. (118 aa) |
| | BAN33974.1 | Molybdopterin biosynthesis protein MoeB. (482 aa) |
| | BAN33973.1 | Hypothetical protein; K01493. (524 aa) |
| | BAN33966.1 | Hypothetical protein. (588 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) |
| | BAN33910.1 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (205 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (223 aa) |
| | BAN33899.1 | Hypothetical protein. (82 aa) |
| | purH | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; K00602. (522 aa) |
| | purD | Phosphoribosylamine--glycine ligase; K01945; Belongs to the GARS family. (431 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (157 aa) |
