STRINGSTRING
AFH42485.1 AFH42485.1 AFH42493.1 AFH42493.1 rpl6 rpl6 AFH42495.1 AFH42495.1 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 rpl29 rpl29 rps3 rps3 rpl22 rpl22 rps19p rps19p AFH42508.1 AFH42508.1 rpl2 rpl2 rpl23 rpl23 rpl4 rpl4 rpl3 rpl3 AFH42514.1 AFH42514.1 rps10 rps10 rps7 rps7 rps12 rps12 rpl30e rpl30e AFH42707.1 AFH42707.1 albA albA AFH42725.1 AFH42725.1 top6A top6A top6B top6B AFH42782.1 AFH42782.1 AFH42783.1 AFH42783.1 rps17e rps17e AFH42807.1 AFH42807.1 AFH42812.1 AFH42812.1 AFH42841.1 AFH42841.1 rpl37e rpl37e AFH42863.1 AFH42863.1 AFH42975.1 AFH42975.1 AFH42980.1 AFH42980.1 AFH43014.1 AFH43014.1 nop10 nop10 rps27e rps27e AFH43080.1 AFH43080.1 priS priS rpl10e rpl10e rpl21e rpl21e rpl15e rpl15e dnaG dnaG AFH43182.1 AFH43182.1 rps8e rps8e AFH43219.1 AFH43219.1 AFH43227.1 AFH43227.1 rps15 rps15 rps19e rps19e rpl39e rpl39e rpl31e rpl31e rpl18a rpl18a nep1 nep1 spt5 spt5 rpl11 rpl11 rpl1 rpl1 rpl10 rpl10 rpl12 rpl12 rpl40e rpl40e rps27ae rps27ae rps24e rps24e AFH43324.1 AFH43324.1 rpl37ae rpl37ae AFH43329.1 AFH43329.1 rfcL rfcL rfcS rfcS AFH43353.1 AFH43353.1 AFH43355.1 AFH43355.1 priL priL AFH42160.1 AFH42160.1 AFH42386.1 AFH42386.1 AFH42394.1 AFH42394.1 AFH42402.1 AFH42402.1 rps3ae rps3ae AFH42434.1 AFH42434.1 rps6e rps6e rpl24e rpl24e rps28e rps28e rpl7ae rpl7ae rps2 rps2 AFH42451.1 AFH42451.1 rpl13 rpl13 rpl18e rpl18e rps11 rps11 rps4 rps4 rps13 rps13 rpl14e rpl14e rpl15 rpl15 rpl30 rpl30 rps5 rps5 rpl18 rpl18 rpl19e rpl19e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFH42485.1Hypothetical protein. (56 aa)
AFH42493.1Ribosomal protein L32e. (129 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (185 aa)
AFH42495.130S ribosomal protein S8P. (131 aa)
rps14SSU ribosomal protein S14AB (rps14AB); Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
rpl550S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (188 aa)
rps4e30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (248 aa)
rpl2450S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (158 aa)
rpl1450S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (138 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (116 aa)
rpl29Ribosomal_L29 domain containing protein; Belongs to the universal ribosomal protein uL29 family. (67 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (251 aa)
rpl2250S ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (138 aa)
AFH42508.1Putative ATPase. (313 aa)
rpl250S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (246 aa)
rpl23Ribosomal protein L25/L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (272 aa)
rpl350S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (347 aa)
AFH42514.1Hypothetical protein. (278 aa)
rps1030S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (108 aa)
rps730S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (200 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30eRibosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family. (91 aa)
AFH42707.1Hypothetical protein. (91 aa)
albAChromatin protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (79 aa)
AFH42725.1Hypothetical protein. (96 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (453 aa)
top6BDNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (561 aa)
AFH42782.1Metallophosphoesterase Mre11-like protein. (419 aa)
AFH42783.1Rad50 zinc hook domain protein. (930 aa)
rps17e30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (68 aa)
AFH42807.1KH, type 1, domain protein. (206 aa)
AFH42812.1Small GTP-binding protein. (339 aa)
AFH42841.1ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (407 aa)
rpl37e50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa)
AFH42863.1DNA polymerase I. (938 aa)
AFH42975.130S ribosomal protein S26e. (95 aa)
AFH42980.1DNA topoisomerase III. (676 aa)
AFH43014.1Hypothetical protein. (178 aa)
nop10Nucleolar RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (64 aa)
rps27e30S ribosomal protein S27e. (66 aa)
AFH43080.150S ribosomal protein L44e. (72 aa)
priSDNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (389 aa)
rpl10e50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (170 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (101 aa)
rpl15e50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (235 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (410 aa)
AFH43182.1Hypothetical protein. (46 aa)
rps8e30S ribosomal protein S8e. (129 aa)
AFH43219.1Hypothetical protein. (93 aa)
AFH43227.1DNA polymerase B region. (541 aa)
rps1530S ribosomal protein S15P. (152 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (154 aa)
rpl39eHypothetical protein; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
rpl31eHypothetical protein; Belongs to the ribosomal protein L31e family. (114 aa)
rpl18a50S ribosomal protein LX. (86 aa)
nep1Ribosome biogenesis protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (240 aa)
spt5Transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (167 aa)
rpl1150S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (167 aa)
rpl150S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa)
rpl10LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (347 aa)
rpl1250S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (99 aa)
rpl40eLSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (56 aa)
rps27aeRibosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. (56 aa)
rps24e30S ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (138 aa)
AFH43324.1Shwachman-Bodian-Diamond syndrome protein. (232 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (86 aa)
AFH43329.1Brix; Probably involved in the biogenesis of the ribosome. (207 aa)
rfcLReplication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (458 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (326 aa)
AFH43353.1Cell division control protein 6; Involved in regulation of DNA replication. (407 aa)
AFH43355.1Putative ATPase. (281 aa)
priLDNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (387 aa)
AFH42160.1Putative circadian clock protein, KaiC; Belongs to the UPF0273 family. (247 aa)
AFH42386.1AAA ATPase. (252 aa)
AFH42394.1RuvB-like 2. (453 aa)
AFH42402.1Family B-type DNA polymerase. (799 aa)
rps3ae30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (214 aa)
AFH42434.1Nucleotide binding protein, PINc. (142 aa)
rps6e30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (223 aa)
rpl24eRibosomal protein L24E; Binds to the 23S rRNA. (59 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (79 aa)
rpl7ae50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (126 aa)
rps230S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (220 aa)
AFH42451.130S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (131 aa)
rpl1350S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (149 aa)
rpl18e50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (125 aa)
rps1130S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (105 aa)
rps4SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (168 aa)
rps1330S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (164 aa)
rpl14e50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (98 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa)
rpl3050S ribosomal protein L30P. (149 aa)
rps5SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (212 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (199 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (153 aa)
Your Current Organism:
Fervidicoccus fontis
NCBI taxonomy Id: 1163730
Other names: Desulfurococcales archaeon Kam940, F. fontis Kam940, Fervidicoccus fontis DSM 19380, Fervidicoccus fontis Kam940, Fervidicoccus fontis str. Kam940, Fervidicoccus fontis strain Kam940
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