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| | iscS | Pyridoxal-dependent decarboxylase. (499 aa) |
| | FAES_0073 | Aminotransferase class I and II. (385 aa) |
| | FAES_0194 | Hypothetical protein. (351 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (523 aa) |
| | tdk | Thymidine kinase. (203 aa) |
| | purD | Phosphoribosylamine/glycine ligase; Belongs to the GARS family. (427 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (229 aa) |
| | FAES_0371 | Putative protein yyaP. (189 aa) |
| | FAES_0427 | 5'-nucleotidase domain protein. (287 aa) |
| | FAES_0428 | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. (310 aa) |
| | thrC | Threonine synthase. (454 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (214 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (275 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (328 aa) |
| | FAES_0484 | Glutamine amidotransferase of anthranilate synthase. (188 aa) |
| | FAES_0485 | Anthranilate synthase. (479 aa) |
| | FAES_0488 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (443 aa) |
| | mtnK | Methylthioribose kinase. (333 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (347 aa) |
| | FAES_0628 | Carbamoyl-phosphate synthase, large subunit. (957 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (359 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (408 aa) |
| | FAES_0675 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (177 aa) |
| | FAES_0678 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (174 aa) |
| | FAES_0724 | Aminotransferase class I and II. (406 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. (171 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (193 aa) |
| | trpF-2 | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (216 aa) |
| | FAES_1010 | Methionine synthase vitamin-B12 independent. (345 aa) |
| | pdxJ | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (240 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (165 aa) |
| | FAES_1179 | Aspartate kinase; Belongs to the aspartokinase family. (448 aa) |
| | FAES_1207 | Phosphoribulokinase/uridine kinase; Belongs to the uridine kinase family. (206 aa) |
| | FAES_1216 | Cysteine synthase B. (328 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (347 aa) |
| | FAES_1222 | Non-canonical purine NTP pyrophosphatase,rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (436 aa) |
| | FAES_1297 | Hypothetical protein. (236 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (229 aa) |
| | FAES_1383 | Riboflavin synthase, alpha subunit. (188 aa) |
| | FAES_1445 | Aspartate kinase. (822 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (267 aa) |
| | FAES_1499 | Putative protein ywjB. (179 aa) |
| | asnB | Asparagine synthase (glutamine-hydrolysing). (617 aa) |
| | FAES_1627 | Aminotransferase class IV. (274 aa) |
| | FAES_1696 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (340 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (424 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa) |
| | FAES_1856 | Hypothetical protein. (219 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (258 aa) |
| | FAES_1963 | Peptidase M20. (361 aa) |
| | FAES_1971 | CMP/dCMP deaminase zinc-binding protein. (166 aa) |
| | FAES_2023 | Competence/damage-inducible protein CinA; Belongs to the CinA family. (425 aa) |
| | FAES_2036 | Hypothetical protein. (152 aa) |
| | FAES_2038 | 5' nucleotidase. (215 aa) |
| | FAES_2043 | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (384 aa) |
| | FAES_2044 | Aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (324 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (264 aa) |
| | ilvE | Branched-chain amino acid aminotransferase. (294 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (273 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) |
| | FAES_2257 | MazG family protein. (262 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (687 aa) |
| | FAES_2494 | Phosphoribosylformylglycinamidine cyclo-ligase. (412 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase,catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (157 aa) |
| | FAES_2531 | DAHP synthetase I/KDSA. (366 aa) |
| | FAES_2666 | L-asparaginase, type I. (350 aa) |
| | mtnN | S-adenosylhomocysteine/5'- methylthioadenosinenucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (257 aa) |
| | pabB | Para-aminobenzoate synthetase component I. (431 aa) |
| | hisB | Histidinol-phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (386 aa) |
| | FAES_2750 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (566 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa) |
| | FAES_2768 | 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. (138 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (213 aa) |
| | FAES_2845 | Cystathionine gamma-lyase. (385 aa) |
| | FAES_2919 | 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. (144 aa) |
| | folE | GTP cyclohydrolase I. (255 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa) |
| | queE | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (211 aa) |
| | mtn | S-adenosylhomocysteine/5'- methylthioadenosinenucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (276 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (231 aa) |
| | pabA | Anthranilate synthase component II. (191 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (291 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (510 aa) |
| | FAES_3156 | Phosphodiesterase/alkaline phosphatase D. (484 aa) |
| | folC | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (431 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2, 6-carboxylateN-succinyltransferase. (158 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamidesy nthase; Belongs to the SAICAR synthetase family. (316 aa) |
| | FAES_3479 | Argininosuccinate lyase. (419 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa) |
| | FAES_3618 | Dihydropteroate synthase. (282 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (316 aa) |
| | FAES_3688 | Aminotransferase class V. (338 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa) |
| | FAES_3703 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (319 aa) |
| | FAES_3713 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. (622 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (758 aa) |
| | FAES_3799 | N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (206 aa) |
| | FAES_3827 | Thiamine pyrophosphokinase. (220 aa) |
| | FAES_3832 | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | FAES_3838 | Alkaline phosphatase. (580 aa) |
| | FAES_3839 | Cystathionine beta-synthase. (458 aa) |
| | FAES_3840 | Hypothetical protein. (261 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (83 aa) |
| | FAES_4047 | DNA (cytosine-5-)-methyltransferase. (709 aa) |
| | FAES_4077 | Cystathionine gamma-synthase. (372 aa) |
| | FAES_4092 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (116 aa) |
| | metZ | Methionine gamma-lyase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (411 aa) |
| | FAES_4159 | Aminotransferase class V; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa) |
| | FAES_4160 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (643 aa) |
| | FAES_4164 | O-acetylhomoserine/O-acetylserinesulfhydrylase. (438 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (353 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | rsgA | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (308 aa) |
| | FAES_4365 | Aminotransferase class I and II. (403 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (326 aa) |
| | FAES_4399 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (425 aa) |
| | FAES_4478 | Prephenate dehydrogenase. (285 aa) |
| | FAES_4479 | Aminotransferase class I and II. (387 aa) |
| | cobB | Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. (233 aa) |
| | FAES_4511 | Uracil phosphoribosyltransferase. (181 aa) |
| | pyrR | Pyrimidine operon attenuation protein / uracil phosphoribosyltransferase. (193 aa) |
| | FAES_4572 | Dihydroorotase, multifunctional complex type. (452 aa) |
| | FAES_4701 | Type 12 methyltransferase. (199 aa) |
| | FAES_4781 | Serine O-acetyltransferase. (314 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (412 aa) |
| | FAES_4819 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein. (315 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (608 aa) |
| | FAES_4825 | Aminotransferase class I and II. (400 aa) |
| | FAES_4828 | Chorismate mutase. (381 aa) |
| | FAES_4886 | Peptidase M23. (232 aa) |
| | FAES_4905 | Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (379 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa) |
| | FAES_4907 | Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (505 aa) |
| | FAES_4908 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (203 aa) |
| | FAES_4909 | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (484 aa) |
| | FAES_4924 | Ketol-acid reductoisomerase. (347 aa) |
| | FAES_4925 | Acetolactate synthase, small subunit. (177 aa) |
| | FAES_4926 | Acetolactate synthase, large subunit,biosynthetic type. (587 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (566 aa) |
| | FAES_4955 | Amidohydrolase. (449 aa) |
| | hisI | phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. (208 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamideisomerase. (243 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (225 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (501 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (195 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (411 aa) |
| | FAES_5085 | Branched-chain amino acid aminotransferase. (356 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (273 aa) |
| | FAES_5227 | Aspartate kinase; Belongs to the aspartokinase family. (422 aa) |
| | ahcY | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (436 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (366 aa) |
| | FAES_5376 | Shikimate dehydrogenase substrate binding domain protein. (251 aa) |
| | FAES_5379 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (350 aa) |
| | FAES_5383 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1259 aa) |
| | FAES_5435 | Putative nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family. (488 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (302 aa) |
| | FAES_5437 | 7,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. (228 aa) |
| | FAES_5439 | NUDIX hydrolase. (166 aa) |
| | FAES_5454 | Uracil phosphoribosyltransferase. (222 aa) |
| | FAES_5487 | Amidophosphoribosyltransferase. (682 aa) |
