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gpmA gpmA FAES_0406 FAES_0406 pfkA pfkA pgk pgk FAES_0835 FAES_0835 FAES_1037 FAES_1037 pdhA pdhA eno eno gpmI gpmI tpiA tpiA FAES_1427 FAES_1427 FAES_1864 FAES_1864 FAES_2088 FAES_2088 nagC nagC FAES_2373 FAES_2373 FAES_2581 FAES_2581 FAES_2732 FAES_2732 FAES_2797 FAES_2797 FAES_2975 FAES_2975 FAES_3061 FAES_3061 FAES_3117 FAES_3117 FAES_3167 FAES_3167 FAES_3443 FAES_3443 FAES_3605 FAES_3605 FAES_3777 FAES_3777 alkH alkH FAES_3830 FAES_3830 pgi pgi mro mro FAES_4625 FAES_4625 FAES_4937 FAES_4937 FAES_5203 FAES_5203 fbp fbp pckA pckA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (201 aa)
FAES_04061-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (319 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
FAES_0835Pyruvate kinase; Belongs to the pyruvate kinase family. (479 aa)
FAES_1037Dihydrolipoamide dehydrogenase. (465 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (348 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
gpmIPhosphoglycerate mutase,2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (524 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
FAES_1427HAD-superfamily hydrolase, subfamily IA, variant 3. (220 aa)
FAES_1864Dihydrolipoamide dehydrogenase. (468 aa)
FAES_2088Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (588 aa)
nagCGlucokinase. (316 aa)
FAES_2373ROK family protein. (298 aa)
FAES_2581Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (586 aa)
FAES_2732ROK family protein. (308 aa)
FAES_2797acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa)
FAES_2975Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (557 aa)
FAES_3061Aldehyde Dehydrogenase. (538 aa)
FAES_3117Aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family. (508 aa)
FAES_3167Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (351 aa)
FAES_3443Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
FAES_3605Glucokinase. (316 aa)
FAES_3777Aldose 1-epimerase. (323 aa)
alkHAldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (508 aa)
FAES_3830Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (554 aa)
mroAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (402 aa)
FAES_4625Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
FAES_4937ROK family protein. (303 aa)
FAES_5203Alcohol dehydrogenase GroES domain protein. (347 aa)
fbpInositolphosphatase/fructose-16-bisphosphatase; Belongs to the FBPase class 1 family. (334 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (540 aa)
Your Current Organism:
Fibrella aestuarina
NCBI taxonomy Id: 1166018
Other names: F. aestuarina BUZ 2, Fibrella aestuarina BUZ 2, Fibrella aestuarina str. BUZ 2, Fibrella aestuarina strain BUZ 2, Flexibacteraceae bacterium BUZ 2
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