81 items (Penicillium digitatum) - STRING interaction network

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDIG_90430	Nucleolar protein 16. (234 aa)
	PDIG_86910	Utp12 domain-containing protein. (833 aa)
	PDIG_84050	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (369 aa)
	PDIG_82370	HEAT repeat protein (DRIM), putative. (2618 aa)
	PDIG_89720	Ribosome biogenesis protein nsa2. (261 aa)
	PDIG_84360	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (714 aa)
	PDIG_71250	rRNA biogenesis protein RRP5, putative. (2158 aa)
	PDIG_61640	TRASH domain-containing protein. (190 aa)
	PDIG_58550	PINc domain-containing protein. (193 aa)
	PDIG_62920	Uncharacterized protein. (741 aa)
	PDIG_59670	Small nucleolar ribonucleoprotein complex subunit (SOF1), putative. (447 aa)
	PDIG_50960	Uncharacterized protein. (372 aa)
	PDIG_89440	Ribosome biogenesis protein Noc4, putative. (549 aa)
	PDIG_50770	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (312 aa)
	PDIG_58530	SnoRNA binding protein, putative. (1031 aa)
	PDIG_45300	Protein MAK16; Belongs to the MAK16 family. (317 aa)
	PDIG_46100	rRNA biogenesis protein rrp36. (345 aa)
	PDIG_46140	Uncharacterized protein. (193 aa)
	PDIG_81600	Nucleolar protein 9. (723 aa)
	PDIG_44130	Pre-rRNA processing protein Tsr1, putative. (803 aa)
	PDIG_78090	Imp4 protein, putative. (293 aa)
	PDIG_42650	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (716 aa)
	PDIG_45670	DEAH-box RNA helicase (Dhr1), putative. (1211 aa)
	PDIG_86220	Small nucleolar ribonucleoprotein complex subunit, putative. (616 aa)
	PDIG_86100	Protein bfr2. (525 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1035 aa)
	PDIG_38460	U3 small nucleolar ribonucleoprotein subunit (Imp3), putative. (188 aa)
	PDIG_73670	RNA helicase. (602 aa)
	PDIG_74870	C2H2-type domain-containing protein. (111 aa)
	PDIG_79090	Ribosomal RNA processing protein, putative. (314 aa)
	PDIG_70940	WD repeat protein. (729 aa)
	PDIG_25610	RIO1 family protein kinase, putative. (644 aa)
	PDIG_65370	ATP dependent RNA helicase (Dbp8), putative; Belongs to the DEAD box helicase family. (520 aa)
	PDIG_28730	Uncharacterized protein. (363 aa)
	PDIG_27250	TGF-beta-inducible nuclear protein 1. (114 aa)
	PDIG_26700	Nucleolar protein 12. (526 aa)
	PDIG_20010	Uncharacterized protein. (274 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (815 aa)
	PDIG_18870	WD repeat protein. (774 aa)
	PDIG_58340	rRNA processing protein Bystin, putative. (493 aa)
	PDIG_18550	Ribosomal small subunit assembly protein, putative. (308 aa)
	PDIG_66950	rRNA processing protein Utp6, putative. (395 aa)
	PDIG_56820	U3 small nucleolar RNA-associated protein Utp11, putative. (307 aa)
	PDIG_13840	ATP-dependent RNA helicase DBP10. (912 aa)
	PDIG_13760	RNA helicase. (808 aa)
	PDIG_06740	Ribosome assembly protein Noc2, putative. (766 aa)
	PDIG_11870	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (698 aa)
	PDIG_19250	U3 small nucleolar RNA-associated protein 22. (1071 aa)
	PDIG_13700	C6 transcription factor, putative. (621 aa)
	PDIG_11860	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (184 aa)
	PDIG_17460	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (260 aa)
	PDIG_60650	Nuclear protein involved in pre-rRNA processing, putative. (330 aa)
	PDIG_15510	CCAAT-box-binding transcription factor. (860 aa)
	PDIG_14570	RNA-3'-phosphate cyclase family protein. (402 aa)
	PDIG_51600	Small nucleolar ribonucleoprotein complex subunit Utp14, putatrive. (957 aa)
	PDIG_12350	Uncharacterized protein. (930 aa)
	PDIG_06780	ATP dependent RNA helicase (Rok1), putative. (723 aa)
	PDIG_05770	WD_REPEATS_REGION domain-containing protein. (956 aa)
	PDIG_05820	rRNA processing protein, putative. (327 aa)
	PDIG_54720	Low-temperature viability protein ltv1. (504 aa)
	PDIG_02820	Ribosomal biogenesis protein Gar2. (460 aa)
	PDIG_44120	Small nucleolar ribonucleoprotein complex subunit, putative. (531 aa)
	PDIG_54040	WD_REPEATS_REGION domain-containing protein. (921 aa)
	PDIG_07100	DEAD/DEAH box helicase, putative. (809 aa)
	PDIG_20020	RNA binding protein. (332 aa)
	PDIG_01110	Small nucleolar ribonucleoprotein complex subunit, putative. (606 aa)
	PDIG_42540	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	PDIG_06210	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (376 aa)
	PDIG_06260	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (506 aa)
	PDIG_48920	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (221 aa)
	PDIG_01030	60S ribosome biogenesis protein Mak11, putative. (491 aa)
	PDIG_47630	rRNA maturation protein (Nop14), putative. (909 aa)
	PDIG_00040	Ribosome biogenesis protein, putative. (336 aa)
	PDIG_34140	Uncharacterized protein. (304 aa)
	PDIG_40300	Uncharacterized protein. (480 aa)
	PDIG_28690	Uncharacterized protein. (169 aa)
	PDIG_28740	60S ribosome biogenesis protein Brx1, putative. (361 aa)
	PDIG_21300	RNA helicase. (627 aa)
	PDIG_14920	Sas10/Utp3 family protein. (624 aa)
	PDIG_15520	Uncharacterized protein. (248 aa)
	PDIG_22360	AAA family ATPase, putative. (751 aa)

Your Current Organism:

Penicillium digitatum

NCBI taxonomy Id: 1170229
Other names: P. digitatum PHI26, Penicillium digitatum PHI26

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NAT10	PDIG_00040	K9FVA9	K9GGA4	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosome biogenesis protein, putative.	0.891
NAT10	PDIG_01030	K9FVA9	K9GEZ0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	60S ribosome biogenesis protein Mak11, putative.	0.584
NAT10	PDIG_01110	K9FVA9	K9GCS0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Small nucleolar ribonucleoprotein complex subunit, putative.	0.994
NAT10	PDIG_02820	K9FVA9	K9GC27	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosomal biogenesis protein Gar2.	0.875
NAT10	PDIG_05770	K9FVA9	K9GAW4	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.994
NAT10	PDIG_05820	K9FVA9	K9GAX0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	rRNA processing protein, putative.	0.603
NAT10	PDIG_06210	K9FVA9	K9GDD0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.994
NAT10	PDIG_06260	K9FVA9	K9GDD7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family.	0.614
NAT10	PDIG_06740	K9FVA9	K9H1D8	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosome assembly protein Noc2, putative.	0.930
NAT10	PDIG_06780	K9FVA9	K9GAG6	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	ATP dependent RNA helicase (Rok1), putative.	0.877
NAT10	PDIG_07100	K9FVA9	K9GCG7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	DEAD/DEAH box helicase, putative.	0.581
NAT10	PDIG_11860	K9FVA9	K9G7S0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.751
NAT10	PDIG_11870	K9FVA9	K9GYH8	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.877
NAT10	PDIG_12350	K9FVA9	K9G9V9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.663
NAT10	PDIG_13760	K9FVA9	K9GSS1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	RNA helicase.	0.870
NAT10	PDIG_13840	K9FVA9	K9G6M7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	ATP-dependent RNA helicase DBP10.	0.852
NAT10	PDIG_14570	K9FVA9	K9G8X2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	RNA-3'-phosphate cyclase family protein.	0.989
NAT10	PDIG_14920	K9FVA9	K9GRX9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Sas10/Utp3 family protein.	0.986
NAT10	PDIG_15510	K9FVA9	K9G8W5	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	CCAAT-box-binding transcription factor.	0.812
NAT10	PDIG_15520	K9FVA9	K9GS30	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.812