(39 nodes) Sulfur metabolism network (Penicillium digitatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	PDIG_35640	Alpha-ketoglutarate-dependent taurine dioxygenase. (377 aa)
	PDIG_22910	Rhodanese domain-containing protein. (517 aa)
	PDIG_17350	Thiosulfate sulfurtransferase, putative. (322 aa)
	PDIG_04380	3'-phosphoadenosine-5'-phosphosulfate reductase Met16, putative. (306 aa)
	PDIG_03080	Acetyltransferase, putative. (295 aa)
	PDIG_90940	AB hydrolase-1 domain-containing protein. (423 aa)
	PDIG_89900	Alpha-ketoglutarate-dependent taurine dioxygenase. (380 aa)
	PDIG_85200	Alpha-ketoglutarate-dependent taurine dioxygenase. (376 aa)
	PDIG_80020	COPII-coated vesicle protein SurF4/Erv29, putative. (303 aa)
	PDIG_77770	O-acetyltransferase, putative. (233 aa)
	PDIG_63050	NADPH-dependent FMN reductase Lot6, putative. (219 aa)
	PDIG_52880	Mitochondrial import inner membrane translocase subunit (TIM22), putative. (178 aa)
	PDIG_90920	Cystathionine gamma-synthase. (588 aa)
	PDIG_52870	Cysteine synthase. (372 aa)
	PDIG_52060	Rhodanese domain-containing protein. (230 aa)
	PDIG_86690	Uncharacterized protein. (531 aa)
	PDIG_44490	3'(2'),5'-bisphosphate nucleotidase. (352 aa)
	PDIG_41510	Lactamase_B domain-containing protein. (371 aa)
	PDIG_76800	Cysteine synthase, putative. (430 aa)
	PDIG_70690	Uncharacterized protein. (196 aa)
	PDIG_28150	Uncharacterized protein. (128 aa)
	PDIG_72040	Flavodoxin-like domain-containing protein. (1526 aa)
	PDIG_23070	Myo-inositol-1(Or 4)-monophosphatase. (353 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
	PDIG_19260	Cystathionine gamma-synthase, putative. (586 aa)
	PDIG_19410	Nuclear envelope pore membrane protein, putative. (1257 aa)
	PDIG_12780	Alpha-ketoglutarate-dependent taurine dioxygenase. (400 aa)
	PDIG_15430	Adenylyl-sulfate kinase. (436 aa)
	PDIG_09850	Luciferase-like monooxygenase, putative. (365 aa)
	PDIG_60020	Inositol phospholipid biosynthesis protein Scs3, putative. (329 aa)
	PDIG_07890	Assimilatory sulfite reductase. (1046 aa)
	PDIG_43520	Homocysteine synthase CysD. (436 aa)
	PDIG_06060	PKS_ER domain-containing protein. (422 aa)
	PDIG_03090	Zn(2)-C6 fungal-type domain-containing protein. (76 aa)
	PDIG_00440	Bis(5'-nucleosyl)-tetraphosphatase, putative. (353 aa)
	PDIG_41520	Pyr_redox_2 domain-containing protein. (440 aa)
	PDIG_33440	TPR_REGION domain-containing protein. (543 aa)
	PDIG_31160	Homoserine O-acetyltransferase, putative. (499 aa)
	PDIG_38330	Acetyltransferase, CysE/LacA/LpxA/NodL family. (211 aa)

Your Current Organism:

Penicillium digitatum

NCBI taxonomy Id: 1170229
Other names: P. digitatum PHI26, Penicillium digitatum PHI26

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MET3	PDIG_00440	K9G5C2	K9GFE3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Bis(5'-nucleosyl)-tetraphosphatase, putative.	0.935
MET3	PDIG_04380	K9G5C2	K9GX12	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	3'-phosphoadenosine-5'-phosphosulfate reductase Met16, putative.	0.968
MET3	PDIG_07890	K9G5C2	K9G998	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Assimilatory sulfite reductase.	0.923
MET3	PDIG_15430	K9G5C2	K9G7U2	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Adenylyl-sulfate kinase.	0.995
MET3	PDIG_17350	K9G5C2	K9GV91	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Thiosulfate sulfurtransferase, putative.	0.448
MET3	PDIG_23070	K9G5C2	K9G4W3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Myo-inositol-1(Or 4)-monophosphatase.	0.923
MET3	PDIG_31160	K9G5C2	K9GIY3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Homoserine O-acetyltransferase, putative.	0.567
MET3	PDIG_43520	K9G5C2	K9GC64	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Homocysteine synthase CysD.	0.530
MET3	PDIG_44490	K9G5C2	K9FS70	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	3'(2'),5'-bisphosphate nucleotidase.	0.932
MET3	PDIG_72040	K9G5C2	K9G2U7	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Flavodoxin-like domain-containing protein.	0.973
MET3	PDIG_90940	K9G5C2	K9F4I7	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	AB hydrolase-1 domain-containing protein.	0.567
PDIG_00440	MET3	K9GFE3	K9G5C2	Bis(5'-nucleosyl)-tetraphosphatase, putative.	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	0.935
PDIG_00440	PDIG_04380	K9GFE3	K9GX12	Bis(5'-nucleosyl)-tetraphosphatase, putative.	3'-phosphoadenosine-5'-phosphosulfate reductase Met16, putative.	0.425
PDIG_00440	PDIG_22910	K9GFE3	K9GS91	Bis(5'-nucleosyl)-tetraphosphatase, putative.	Rhodanese domain-containing protein.	0.459
PDIG_00440	PDIG_52870	K9GFE3	K9FP99	Bis(5'-nucleosyl)-tetraphosphatase, putative.	Cysteine synthase.	0.459
PDIG_00440	PDIG_60020	K9GFE3	K9G927	Bis(5'-nucleosyl)-tetraphosphatase, putative.	Inositol phospholipid biosynthesis protein Scs3, putative.	0.718
PDIG_00440	PDIG_76800	K9GFE3	K9FUR8	Bis(5'-nucleosyl)-tetraphosphatase, putative.	Cysteine synthase, putative.	0.459
PDIG_03080	PDIG_03090	K9H2M7	K9GDU6	Acetyltransferase, putative.	Zn(2)-C6 fungal-type domain-containing protein.	0.401
PDIG_03080	PDIG_22910	K9H2M7	K9GS91	Acetyltransferase, putative.	Rhodanese domain-containing protein.	0.650
PDIG_03080	PDIG_52870	K9H2M7	K9FP99	Acetyltransferase, putative.	Cysteine synthase.	0.650