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dapF dapF argC argC argH argH AFZ01859.1 AFZ01859.1 argG argG dapA dapA dapL dapL argB argB dapB dapB argD argD argJ argJ AFZ03880.1 AFZ03880.1 lysA lysA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Your Input:
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (279 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (352 aa)
argHPFAM: Lyase; TIGRFAM: argininosuccinate lyase; COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR009049:IPR022761; KEGG: ava:Ava_1807 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase. (464 aa)
AFZ01859.1LL-diaminopimelate aminotransferase apoenzyme; PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ava:Ava_0017 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: LL-diaminopimelate aminotransferase apoenzyme. (394 aa)
argGPFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: ava:Ava_2068 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
dapLLL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (408 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (298 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (278 aa)
argDPFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine transaminases; COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: npu:Npun_R4958 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (425 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (423 aa)
AFZ03880.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (306 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (465 aa)
Your Current Organism:
Calothrix sp. PCC6303
NCBI taxonomy Id: 1170562
Other names: C. sp. PCC 6303, Calothrix sp. (ATCC 29156), Calothrix sp. (PCC 6303), Calothrix sp. ATCC 29156, Calothrix sp. PCC 6303
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